/seqprg/slib/bin/fasta3_t -n -w 80 -m 6 -q @ %prm FASTA searches a protein or DNA sequence data bank version 3.1t02 March, 1998 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 @: 1575 nt QUERY sequence vs GB105.0 other Mammal library searching /seqlib2/gcggenbank/gb_pr1.seq 6 library searching /seqlib2/gcggenbank/gb_pr2.seq 6 library searching /seqlib2/gcggenbank/gb_ro.seq 6 library searching /seqlib2/gcggenbank/gb_om.seq 6 library opt E() < 20 69 0:= 22 3 0:= one = represents 253 library sequences 24 18 0:= 26 34 3:* 28 62 31:* 30 124 187:* 32 404 723:==* 34 1041 1961:===== * 36 2699 4027:=========== * 38 6360 6655:==========================* 40 9509 9283:====================================*= 42 14697 11347:============================================*============== 44 15164 12517:=================================================*========== 46 13416 12749:==================================================*=== 48 11710 12206:=============================================== * 50 10338 11138:========================================= * 52 8556 9792:================================== * 54 7819 8364:=============================== * 56 6173 6986:========================= * 58 5939 5736:======================*= 60 3971 4646:================ * 62 3556 3725:==============* 64 2645 2962:===========* 66 2286 2341:=========* 68 1839 1842:=======* 70 1423 1443:=====* 72 1149 1128:====* 74 1030 879:===*= 76 796 684:==*= 78 808 532:==*= 80 469 413:=* 82 347 316:=* 84 295 250:*= 86 265 194:*= 88 165 150:* inset = represents 3 library sequences 90 128 116:* 92 117 90:* :=============================*========= 94 87 69:* :======================*====== 96 58 54:* :=================*== 98 37 42:* :=============* 100 42 32:* :==========*=== 102 29 25:* :========*= 104 26 19:* :======*== 106 16 15:* :====*= 108 15 12:* :===*= 110 8 9:* :==* 112 11 7:* :==*= 114 6 5:* :=* 116 5 4:* :=* 118 3 3:* :* >120 65 2:* :*===================== 236494278 residues in 135138 sequences statistics extrapolated from 50000 to 135722 sequences Expectation_n fit: rho(ln(x))= 7.8016+/-0.000363; mu= 8.8694+/- 0.023; mean_var=142.6619+/-25.012, Z-trim: 53 B-trim: 1607 in 1/89 Kolmogorov-Smirnov statistic: 0.0298 (N=29) at 46 FASTA (3.14 April, 1998) function (optimized, DNA matrix) ktup: 6 join: 64, opt: 49, gap-pen: -16/ -4, width: 16 reg.-scaled Scan time: 435.933 --------------------------------------------------------------------------- The best scores are: initn init1 opt z-sc E(135722) HSCATHL X12451 Human mrRNA for pro-cathepsin L (major excrete (1575) 7875 7875 7875 6587.7 0 align HUMPROLA M20496 Human cathepsin L gene, complete cds. 5/95 (1404) 6060 5030 6317 5284.0 1.3e-287 align PIGPCL D37917 Boar mRNA for porcine cathepsin L, complete cds (1378) 3830 2303 4066 3399.5 1.2e-182 align BTCATHEPL X91755 B.taurus mRNA for cathepsin L. 9/96 (1388) 3953 2215 3992 3337.5 3.4e-179 align RNCATHL Y00697 Rat mRNA for cathepsin L (EC 3.4.22.15). 9/93 (1386) 3015 2903 3292 2751.5 1.5e-146 align MUSPROL M20495 Mouse cathepsin L gene, complete cds, clones a (1413) 3121 2944 3195 2670.2 5e-142 align MMMEPR X06086 Mouse mRNA for major excreted protein (MEP). 3/ (1374) 3075 2898 3168 2647.7 9.1e-141 align MUSCPR J02583 Mouse cysteine proteinase mRNA, complete cds. 6 (1276) 3021 2898 3168 2648.2 9.2e-141 align RNU16858 U16858 Rattus norvegicus testin mRNA, complete cds. (1371) 2511 2401 2586 2160.5 1.3e-113 align S85184 Cyclic Protein-2=cathepsin L proenzyme [rats, Sertoli (1790) 2340 2228 2505 2090.9 7.2e-110 align MMMEPR1 X04392 Mouse mRNA fragment for major excreted protein ( 638) 1894 1894 1894 1586.1 2.7e-81 align RATCATLR L14776 Rattus norvegicus cathepsin-related protein m ( 911) 1461 1049 1555 1300.0 1.6e-65 align HUMCAPLL L07772 Human cathepsin-L like (CTSLL) gene, exons 1 (7211) 3622 949 1481 1224.5 3.3e-62 align HUMCATHLA L06426 Human cathepsin L (CTSL) gene, exon 1, intro (1484) 1400 1400 1400 1167.0 2.5e-58 align CATPDP M31652 Cat progesterone-dependent protein mRNA, partia ( 421) 1332 1332 1343 1127.5 1.4e-55 align RABOC2 D14036 Rabbit mRNA for OC-2 protein, complete cds. 2/9 (1599) 775 206 1138 947.2 4.1e-46 align S39127 cathepsin S=cysteine proteinase [human, testis, mRNA, (1784) 800 319 1076 894.5 3.2e-43 align HUMCATS M90696 Human cathepsin S (CTSS) mRNA, complete cds. 7 (1763) 800 319 1067 887.1 8.3e-43 align HUMCATSS M86553 Human cathepsin S mRNA, complete cds. 2/92 (1255) 783 319 1058 881.8 2.3e-42 align S93414 cathepsin S=elastinolytic cysteine protease [human, a (1255) 783 319 1058 881.8 2.3e-42 align AF038546 Mus musculus cathepsin S precursor, mRNA, complete (1305) 990 467 989 823.7 3.8e-39 align RATCTHS L03201 Rattus norvegicus cathepsin S mRNA, complete c (1330) 661 301 986 821.1 5.2e-39 align HSOC2RNA X82153 H.sapiens mRNA for cathepsin O. 4/95 (1669) 806 322 958 796.2 1e-37 align HSU13665 U13665 Human cathepsin O (CTSO) mRNA, complete cds. (1661) 806 322 958 796.2 1e-37 align HSU20280 U20280 Human cathepsin X mRNA, complete cds. 4/96 (1597) 806 322 958 796.5 1e-37 align S79895 OC2=cathepsin O2 [human, spleen, mRNA, 1482 nt]. 2/96 (1482) 806 322 958 797.0 1e-37 align MMPPCATHK X94444 M.musculus mRNA for preprocathepsin K. 1/97 ( 990) 642 350 898 749.4 7e-35 align AF010306 Rattus norvegicus cathepsin K mRNA, complete cds. 8 (1248) 605 341 887 738.6 2.2e-34 align HUMCTSLL3X L25629 Human cathepsin-L-like (CTSLL3) mRNA. 10/93 ( 208) 766 455 829 701.8 1.5e-31 align HUMCTSLL2X L25628 Human cathepsin-L-like (CTSLL2) mRNA. 10/93 ( 208) 800 416 820 694.2 3.9e-31 align BOVCATS M95211 Bovine cathepsin S (catS) mRNA, partial cds. 8 (1235) 409 176 703 584.7 8.3e-26 align BTCATPS X62001 B.taurus mRNA for cathepsin S. 6/93 (1234) 409 176 703 584.7 8.3e-26 align HSCATLR1 X05256 Human mRNA fragment for cathepsin L N-termina ( 126) 630 630 630 538.4 3.1e-22 align SSAF001169 AF001169 Sus scrofa preprocathepsin H mRNA, comple (1149) 179 113 574 477.1 8.7e-20 align HSCATHH X16832 Human mRNA for cathepsin H (EC 3.4.22.16). 3/9 (1399) 143 82 513 424.8 5.9e-17 align MMCTSH U06119 Mus musculus cathepsin H prepropeptide (ctsH) m (1381) 84 84 475 393.0 3.5e-15 align HSCATHEP5 U07373 Human cathepsin S gene, exon 5, partial cds. ( 461) 349 194 463 390.2 1.5e-14 align HSCATH X07549 Human mRNA for cathepsin H (E.C.3.4.22.16.). 11 (1106) 81 81 456 378.6 2.8e-14 align MMCTLA2A X15591 Mouse ctla-2-alpha mRNA, homolog. to cysteine ( 664) 390 390 422 353.4 1.2e-12 align MMCTLA2B X15592 Mouse ctla-2-beta mRNA, homolog. to cysteine ( 777) 373 373 404 337.3 7.9e-12 align AF025476 Rattus norvegicus cathepsin L gene, partial cds. 10 (3198) 190 190 347 280.4 2.8e-09 align MMTSP X17071 Mouse mRNA for a trophoblast-specific protein. 3 ( 707) 297 160 273 228.3 1e-05 align HSCATHCGE X87212 H.sapiens mRNA for cathepsin C. 11/95 (1838) 128 81 208 167.6 0.0095 align RATCATC D90404 Rat mRNA for cathepsin C. 5/92 (1850) 114 114 204 164.2 0.015 align HSU79415 U79415 Homo sapiens prepro dipeptidyl peptidase I (D (4715) 81 81 202 156.4 0.015 align HSAF001550 AF001550 Homo sapiens chromosome 16 BAC clone CIT9 (78416) 242 81 188 126.4 0.044 align AC000080 Homo sapiens Chromosome 22q11.2 Cosmid Clone 56c In (44298) 152 101 181 124.2 0.1 align MMU89269 U89269 Mus musculus preprodipeptidyl peptidase I mRN (1850) 105 105 177 141.6 0.26 align HSU51269 U51269 Human armadillo repeat protein mRNA, complete (4031) 101 101 174 134.0 0.32 align MMU74683 U74683 Mus musculus dipeptidyl peptidase I precursor (1767) 81 81 174 139.4 0.37 align HSNFIL6 X52560 Human gene for nuclear factor NF-IL6. 4/97 (1910) 79 79 166 132.2 0.85 align MUSC3A1A M18933 Mouse alpha-1 type-III collagen mRNA, 5' end. (1485) 60 60 165 133.0 0.99 align HSL145E5 Z68162 Human DNA sequence from cosmid L145E5, Huntin (25719) 163 97 158 108.5 1.3 align MMCYES X67677 M.musculus c-yes mRNA. 3/93 (4550) 163 112 160 121.5 1.4 align AC003954 Homo sapiens chromosome 5, Pac clone 162o17 (LBNL H (78416) 165 119 155 98.7 1.5 align HSCATHEP3 U07371 Human cathepsin S gene, exon 3, partial cds. ( 294) 74 74 163 141.9 1.6 align --------------------------------------------------------------------------- >>>@, 1575 nt vs %prm library >>HSCATHL X12451 Human mrRNA for pro-cathepsin L (major excreted protein MEP) (1575 nt) initn: 7875 init1: 7875 opt: 7875 Z-score: 6587.7 expect() 0 100.000% identity in 1575 nt overlap Entrez lookup Re-search database >HSCATH 1-1575:---------------------------------------------------------------------: 10 20 30 40 50 60 70 80 QUERY AGAACCGCGACCTCCGCAACCTTGAGCGGCATCCGTGGAGTGCGCCTGCAGCTACGACCGCAGCAGGAAAGCGCCGCCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH AGAACCGCGACCTCCGCAACCTTGAGCGGCATCCGTGGAGTGCGCCTGCAGCTACGACCGCAGCAGGAAAGCGCCGCCGG 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 QUERY CCAGGCCCAGCTGTGGCCGGACAGGGACTGGAAGAGAGGACGCGGTCGAGTAGGTGTGCACCAGCCCTGGCAACGAGAGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH CCAGGCCCAGCTGTGGCCGGACAGGGACTGGAAGAGAGGACGCGGTCGAGTAGGTGTGCACCAGCCCTGGCAACGAGAGC 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 QUERY GTCTACCCCGAACTCTGCTGGCCTTGAGGTGGGGAAGCCGGGGAGGGCAGTTGAGGACCCCGCGGAGGCGCGTGACTGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH GTCTACCCCGAACTCTGCTGGCCTTGAGGTGGGGAAGCCGGGGAGGGCAGTTGAGGACCCCGCGGAGGCGCGTGACTGGT 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 QUERY TGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGTTTTAAAACATGAATCCTACACTCATCCTTGCTGCCTTTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH TGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGTTTTAAAACATGAATCCTACACTCATCCTTGCTGCCTTTTG 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 QUERY CCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH CCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACA 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 QUERY GATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH GATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAG 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 QUERY GAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH GAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGT 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 QUERY GATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH GATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTG 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 QUERY TGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH TGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACT 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 QUERY GGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH GGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGG 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 QUERY GCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH GCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACT 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 QUERY CTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH CTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGC 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 QUERY TTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH TTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 QUERY AGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH AGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTG 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 QUERY TGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH TGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAA 1130 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 1270 1280 QUERY GAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH GAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCC 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 QUERY CACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCAGTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH CACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCAGTC 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 QUERY TACCAGCCCCCGCTGTGTCGGATACACACTCGAATCATTGAAGATCCGAGTGTGATTTGAATTCTGTGATATTTTCACAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH TACCAGCCCCCGCTGTGTCGGATACACACTCGAATCATTGAAGATCCGAGTGTGATTTGAATTCTGTGATATTTTCACAC 1370 1380 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 1510 1520 QUERY TGGTAAATGTTACCTCTATTTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACTTACTGACTTTGCATTTTCGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH TGGTAAATGTTACCTCTATTTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACTTACTGACTTTGCATTTTCGT 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 1570 QUERY TTTTAAAAGGATGTATAAATTTTTACCTGTTTAAATAAAATTTAATTTCAAATGT ::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATH TTTTAAAAGGATGTATAAATTTTTACCTGTTTAAATAAAATTTAATTTCAAATGT 1530 1540 1550 1560 1570 --------------------------------------------------------------------------- >>HUMPROLA M20496 Human cathepsin L gene, complete cds. 5/95 (1404 nt) initn: 6060 init1: 5030 opt: 6317 Z-score: 5284.0 expect() 1.3e-287 99.531% identity in 1279 nt overlap Entrez lookup Re-search database >HUMPRO 283-1561: --------------------------------------------------------: 250 260 270 280 290 300 310 320 QUERY AGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGTTTTAAAACATGAATCCTACACTCATCCTTGCTGCCTTTTGCC ::: : :::::::::::::::::::::::::::::::::: HUMPRO TTTTATTCTACCATGGTGGCCCTAATTTTTCAGGGGGCAGTAAGATATGAATCCTACACTCATCCTTGCTGCCTTTTGCC 90 100 110 120 130 140 150 160 330 340 350 360 370 380 390 400 QUERY TGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO TGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGA 170 180 190 200 210 220 230 240 410 420 430 440 450 460 470 480 QUERY TTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO TTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGA 250 260 270 280 290 300 310 320 490 500 510 520 530 540 550 560 QUERY ATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO ATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGA 330 340 350 360 370 380 390 400 570 580 590 600 610 620 630 640 QUERY TGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO TGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTG 410 420 430 440 450 460 470 480 650 660 670 680 690 700 710 720 QUERY GATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO GATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGG 490 500 510 520 530 540 550 560 730 740 750 760 770 780 790 800 QUERY TGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO TGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGC 570 580 590 600 610 620 630 640 810 820 830 840 850 860 870 880 QUERY CTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO CTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCT 650 660 670 680 690 700 710 720 890 900 910 920 930 940 950 960 QUERY GAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO GAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTT 730 740 750 760 770 780 790 800 970 980 990 1000 1010 1020 1030 1040 QUERY TGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO TGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAG 810 820 830 840 850 860 870 880 1050 1060 1070 1080 1090 1100 1110 1120 QUERY GTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO GTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTG 890 900 910 920 930 940 950 960 1130 1140 1150 1160 1170 1180 1190 1200 QUERY CTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO CTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGA 970 980 990 1000 1010 1020 1030 1040 1210 1220 1230 1240 1250 1260 1270 1280 QUERY ATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO ATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCA 1050 1060 1070 1080 1090 1100 1110 1120 1290 1300 1310 1320 1330 1340 1350 1360 QUERY CTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCAGTCTA ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: HUMPRO CTGTGTGAGCT-GTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAAT---TCTTCAGTCTA 1130 1140 1150 1160 1170 1180 1190 1200 1370 1380 1390 1400 1410 1420 1430 1440 QUERY CCAGCCCCCGCTGTGTCGGATACACACTCGAATCATTGAAGATCCGAGTGTGATTTGAATTCTGTGATATTTTCACACTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO CCAGCCCCCGCTGTGTCGGATACACACTCGAATCATTGAAGATCCGAGTGTGATTTGAATTCTGTGATATTTTCACACTG 1210 1220 1230 1240 1250 1260 1270 1280 1450 1460 1470 1480 1490 1500 1510 1520 QUERY GTAAATGTTACCTCTATTTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACTTACTGACTTTGCATTTTCGTTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMPRO GTAAATGTTACCTCTATTTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACTTACTGACTTTGCATTTTCGTTT 1290 1300 1310 1320 1330 1340 1350 1360 1530 1540 1550 1560 1570 QUERY TTAAAAGGATGTATAAATTTTTACCTGTTTAAATAAAATTTAATTTCAAATGT ::::::::::::::::::::::::::::::::::::::: HUMPRO TTAAAAGGATGTATAAATTTTTACCTGTTTAAATAAAATCG 1370 1380 1390 1400 --------------------------------------------------------------------------- >>PIGPCL D37917 Boar mRNA for porcine cathepsin L, complete cds. 1/97 (1378 nt) initn: 3830 init1: 2303 opt: 4066 Z-score: 3399.5 expect() 1.2e-182 81.148% identity in 1289 nt overlap Entrez lookup Re-search database >PIGPCL 256-1526: --------------------------------------------------------- : 220 230 240 250 260 270 280 290 QUERY GACCCCGCGGAGGCGCGTGACTGGTTGAGCGGGCAGGCCAGCCTCCG-AGCCG-GGTGGACACAGG-TTTTAAAACATGA :::: :: ::: : :: : : :::: :::: :::::::: PIGPCL CCACCGCCAACTTAGGAGAGATACGTACGCCGTGGAGTGCGCCTGCGTAGCGGTGGAAGCCGCAGGTTTTTGAAACATGA 10 20 30 40 50 60 70 80 300 310 320 330 340 350 360 370 QUERY ATCCTACACTCATCCTTGCTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAG : ::: ::::: :::: : ::: ::::: ::::::: ::::::::: ::: :: : ::::::: : :::::: ::: : PIGPCL AACCTTCACTCTTCCTGACCGCCCTTTGCTTGGGAATAGCCTCAGCTGCTCCAAAACTTGATCAAAATTTAGATGCAGAC 90 100 110 120 130 140 150 160 380 390 400 410 420 430 440 450 QUERY TGGACCAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAA ::: :::::::::::: : ::: ::: : :: ::::::::::::::::::::: ::::::: :: ::::::::::: PIGPCL TGGTACAAGTGGAAGGCAACACACGGGAGACTCTATGGCATGAATGAAGAAGGATGGCGGAGAGCCGTATGGGAGAAGAA 170 180 190 200 210 220 230 240 460 470 480 490 500 510 520 530 QUERY CATGAAGATGATTGAACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAG ::::: ::::::::::::::::::::::::::::: :::::::::: :::::: ::::::::::: :::::::: : PIGPCL TATGAAAATGATTGAACTGCACAATCAGGAATACAGCCAAGGGAAACATGGCTTCAGCATGGCCATGAATGCCTTTGGTG 250 260 270 280 290 300 310 320 540 550 560 570 580 590 600 610 QUERY ACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAA ::::::::: :::::::::::::::::::::::::::::::::::::: :::: :: :::::::::::::::::: ::: PIGPCL ACATGACCAATGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAACCAGAAGCACAAGAAGGGGAAAGTGTTCCACGAA 330 340 350 360 370 380 390 400 620 630 640 650 660 670 680 690 QUERY CCTCTGTTTTATGAGGCCCCCAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTG ::::: :: ::::: ::::: ::: :: ::::::::::: :::::::: :: ::: : :::::::::::::::::::: PIGPCL TCTCTGGTTCTTGAGGTCCCCAAATCGGTAGATTGGAGAGAAAAAGGCTATGTCACTGCCGTGAAGAATCAGGGTCAGTG 410 420 430 440 450 460 470 480 700 710 720 730 740 750 760 770 QUERY TGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGA :::::::::::::::::::::::: :: :: :: :: ::::::::::::::::::::::: :: : :::: : ::::::: PIGPCL TGGTTCTTGTTGGGCTTTTAGTGCCACCGGCGCCCTCGAAGGACAGATGTTCCGGAAAACCGGCAAGCTTGTTTCACTGA 490 500 510 520 530 540 550 560 780 790 800 810 820 830 840 850 QUERY GTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAG :::::::::: ::::: ::::: ::: :::::::::::::: : :::::::::::::::::::::::: :::: :::::: PIGPCL GTGAGCAGAACCTGGTGGACTGTTCTCGGCCTCAAGGCAATCAGGGCTGCAATGGTGGCCTAATGGATAATGCCTTCCAG 570 580 590 600 610 620 630 640 860 870 880 890 900 910 920 QUERY TATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAG-AAGAATC--CTGTAAGTACAA :: :: :::: ::::::::::::::: : :::::::::::::: :: : :: : :: :: : ::::: :: :: PIGPCL TACGTGAAGGACAATGGAGGCCTGGACACAGAGGAATCCTATCCGTACCTTGGAAGGGAAACAAACAGCTGTACCTATAA 650 660 670 680 690 700 710 720 930 940 950 960 970 980 990 1000 QUERY TCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAA ::: ::: ::::: ::: :: ::::::::::: :::::::::::: ::: :::::::::::: ::::::::::: :::: PIGPCL GCCCGAGTGTTCTGCTGCCAACGACACCGGCTTCGTGGACATCCCTCAGCGGGAGAAGGCCCTTATGAAGGCAGTCGCAA 730 740 750 760 770 780 790 800 1010 1020 1030 1040 1050 1060 1070 1080 QUERY CTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCA ::::::::::::: ::::::::::::::::: :: ::: :: :::: ::::::::: ::::::::::: ::: ::: PIGPCL CTGTGGGGCCCATCTCTGTTGCTATTGATGCGGGCCATTCATCTTTCCAGTTCTATAAGTCAGGCATTTATTATGATCCA 810 820 830 840 850 860 870 880 1090 1100 1110 1120 1130 1140 1150 1160 QUERY GACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAA ::::: ::::: ::::: ::::::::::::: ::::::::::::: :: :::::: : :: :: ::: ::: :: ::: PIGPCL GACTGCAGCAGCAAAGACCTGGATCATGGTGTTTTGGTGGTTGGCTATGGCTTTGAAGGAACTGATTCAAATAGCAGTAA 890 900 910 920 930 940 950 960 1170 1180 1190 1200 1210 1220 1230 1240 QUERY ATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACC :: :::: : :: :::::::: :::::: :::::::::: : ::::::::::: ::::::::::::: :: :::: PIGPCL ATTTTGGATTGTCAAGAACAGTTGGGGTCCAGAATGGGGCTGGAACGGCTACGTAAAAATGGCCAAAGACCAGAACAACC 970 980 990 1000 1010 1020 1030 1040 1250 1260 1270 1280 1290 1300 1310 1320 QUERY ATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATG : ::::::::: :: ::::::::::::: ::::: :::::::::: ::: ::::: : ::::: ::: ::: PIGPCL ACTGTGGAATTTCCACAGCAGCCAGCTATCCCACCGTGTGAGCTGACGGATGGTGAGAATAGAGGAC----CTGAGGACA 1050 1060 1070 1080 1090 1100 1110 1330 1340 1350 1360 1370 1380 1390 1400 QUERY GCGCATGCATGGGAGGAA-TTCATCTTCAGTCT-ACC-AGCCCCCGCTGTGTCGGAT-ACACACTCGAATCATTGAAGAT :: ::: ::::::: :: ::::: : :: ::: : ::: ::::: ::: : ::::: :::::::::: ::: PIGPCL GCACAT---CTGGAGGAATTTTATCTTAAAACTGACCAAACCCTTATTGTGTAAGATAAGACACTTGAATCATTGAGGAT 1120 1130 1140 1150 1160 1170 1180 1190 1410 1420 1430 1440 1450 1460 1470 1480 QUERY CCGAG-TGTGATTTGAATTCTGTGATATTTTCACACTGGT-AAATGTTACCTCTATTTTAATTAC-TGCTATAAATAGGT :: :: ::::: ::::::::::::: ::::: : : ::: :::::::::: ::: ::::::::: :: ::::::::: : PIGPCL CCAAGTTGTGACTTGAATTCTGTGACATTTTTATAAGGGTAAAATGTTACCACTACTTTAATTACTTGTTATAAATAGCT 1200 1210 1220 1230 1240 1250 1260 1270 1490 1500 1510 1520 1530 1540 1550 QUERY TTATATTATT---GATTCACTTACTGACTTT--GCATTTTCGTTTTTAAAAGGATGTATAAATTTTTACCTGTTTAAATA ::::: : :: :::::: : : ::: : : :::: :::: : PIGPCL TTATAATGTTGAAGATTCATTGCTTAACTCTAAGACTTTTGAATTTTCATTTTTTTAAAGGATGTATAAAACTTTACCTT 1280 1290 1300 1310 1320 1330 1340 1350 1560 1570 QUERY AAATTTAATTTCAAATGT PIGPCL TTAAAATAAATTTGAATTCAGTAC 1360 1370 --------------------------------------------------------------------------- >>BTCATHEPL X91755 B.taurus mRNA for cathepsin L. 9/96 (1388 nt) initn: 3953 init1: 2215 opt: 3992 Z-score: 3337.5 expect() 3.4e-179 78.987% identity in 1342 nt overlap Entrez lookup Re-search database >BTCATH 242-1572: ----------------------------------------------------------: 210 220 230 240 250 260 270 280 QUERY GGAGGGCAGTTGAGGACCCCGCGGAGGCGCGTGACTGGTTGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGTT :: :: : :: : :::: : :: : : ::: :: BTCATH ATTCGGCACGAGGGCGACCTTTGGAGAGAGATAAACGTGCGACCGTGGAGTGC-GCCTGCAGCTTTGGAAGCCGCAGTTT 10 20 30 40 50 60 70 80 290 300 310 320 330 340 350 360 QUERY TTAAAACATGAATCCTACACTCATCCTTGCTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTT :: ::: ::::::::: :: :: :::: ::: : ::::: ::::: : :: :::::: ::: : : :::::: : :: BTCATH TTGAAATATGAATCCTTCATTCTTCCTGACTGTCCTTTGCTTGGGAGTAGCATCAGCTGCTCCCAAACTTGATCCAAATT 90 100 110 120 130 140 150 160 370 380 390 400 410 420 430 440 QUERY TAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTG :::: ::::: ::: : :::::::::: : :::: :: ::::: :::::::::::::::: :::::::::::::::: BTCATH TAGATGCACATTGGCACCAGTGGAAGGCAACTCACAGGAGGTTATATGGCATGAATGAAGAAGAATGGAGGAGAGCAGTG 170 180 190 200 210 220 230 240 450 460 470 480 490 500 510 520 QUERY TGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAA ::::::::::: : ::: :: ::::: ::::: :::::::::::::: ::::::::::: ::: ::::: ::::: BTCATH TGGGAGAAGAATAAGAAAATAATTGACCTGCATAATCAGGAATACAGCGAAGGGAAACATGCGTTCCGCATGGCAATGAA 250 260 270 280 290 300 310 320 530 540 550 560 570 580 590 600 QUERY CGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAG :::::::: :::::::::: ::::::::: ::::::::::::::::: :::::::: : :::: : :::::::::: BTCATH TGCCTTTGGTGACATGACCAATGAAGAATTTAGGCAGGTGATGAATGGTTTTCAAAATCAGAAGCATAAGAAGGGGAAAC 330 340 350 360 370 380 390 400 610 620 630 640 650 660 670 680 QUERY TGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAAT :::: :: :::::::: :: ::: : ::::: :::::::::::::: :::::::::: :: ::::::::::::::: BTCATH TGTTTCATGAACCTCTCCTTGTTGACGTCCCCAAATCTGTGGATTGGACTAAGAAAGGCTATGTAACTCCTGTGAAGAAT 410 420 430 440 450 460 470 480 690 700 710 720 730 740 750 760 QUERY CAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCT :::::::::::::::::::::::::: :::::::: :::::::::::::::::::::::::::::::::::::: : :: BTCATH CAGGGTCAGTGTGGTTCTTGTTGGGCGTTTAGTGCCACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGCAAACT 490 500 510 520 530 540 550 560 770 780 790 800 810 820 830 840 QUERY TATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATT : : :::::::::::::: :: ::::: ::::::::: :: ::::::::::: : :: ::::::::::::::::::::: BTCATH TGTTTCACTGAGTGAGCAAAACCTGGTGGACTGCTCTCGGGCTCAAGGCAATCAGGGTTGCAATGGTGGCCTAATGGATA 570 580 590 600 610 620 630 640 850 860 870 880 890 900 910 QUERY ATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAGA---AGAATCC :::: ::::::::: :: :::: :: :::::::::::::: :::::::: ::::::::: ::::: :: : : : BTCATH ATGCCTTCCAGTATATTAAGGACAACGGAGGCCTGGACTCAGAGGAATCTTATCCATATCTTGCAACGGACACAAATAGC 650 660 670 680 690 700 710 720 920 930 940 950 960 970 980 990 QUERY TGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAA ::::: :: :: :: ::: ::::: :: :::::::: ::::: :: ::::::::: ::: :::::::::::: ::::: BTCATH TGTAACTATAAGCCTGAGTGTTCTGCCGCCAATGACACTGGCTTCGTTGACATCCCTCAGCGGGAGAAGGCCCTTATGAA 730 740 750 760 770 780 790 800 1000 1010 1020 1030 1040 1050 1060 1070 QUERY GGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTT :::::: ::::::::::: ::::: :::::::::::::::::::: ::: ::::::: :::::::::: ::: :::: BTCATH GGCAGTGGCAACTGTGGGCCCCATCTCTGTTGCTATTGATGCAGGCCATACATCCTTCCAGTTCTATAAATCAGGTATTT 810 820 830 840 850 860 870 880 1080 1090 1100 1110 1120 1130 1140 1150 QUERY ATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCA ::: ::: ::::: :: ::: : ::::: ::::::::::::: ::::::::::::: :: :::::: : ::::: ::: BTCATH ATTATGATCCAGATTGCAGCTGCAAAGACCTGGATCATGGTGTTTTGGTGGTTGGCTATGGCTTTGAAGGAACAGATTCA 890 900 910 920 930 940 950 960 1160 1170 1180 1190 1200 1210 1220 1230 QUERY GATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGA :::::::::::: ::: : :: :::::::: :::::: :::::::::: : ::::::::: :: ::::::::::: BTCATH AATAACAATAAATTCTGGATTGTCAAGAACAGTTGGGGTCCAGAATGGGGCTGGAATGGCTACGTGAAAATGGCCAAAGA 970 980 990 1000 1010 1020 1030 1040 1240 1250 1260 1270 1280 1290 1300 1310 QUERY CCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTT :: :: :::::::::::::::::: ::::::::::::: :: ::::: ::::::: :::: ::::::: ::::::: BTCATH CCAGAACAACCATTGTGGAATTGCCACAGCAGCCAGCTATCCAACTGTTTGAGCTGATGGATGGTGATGGTAGAGGACTT 1050 1060 1070 1080 1090 1100 1110 1120 1320 1330 1340 1350 1360 1370 1380 1390 QUERY GACTGGGGATGGCGCATGCATGGGAGGAA-TTCATCTTCAGTCT-ACCAGCCCCCGCTGTGTCGGAT-ACACACTCGAAT :: ::: :: :: ::::::: :: ::::: : :: :::: ::: :: : ::: : ::::: :::: BTCATH GA----GGACAGCCTAT---CTGGAGGAATTTTATCTTAAAACTGACCAAACCCTTACGTATAAGATCATACACTTGAAT 1130 1140 1150 1160 1170 1180 1190 1400 1410 1420 1430 1440 1450 1460 1470 QUERY CATTGAAGATCCGAG-TGTGATTTGAATTCTGTGA-TATTTTCACACTGGT-AAATGTTACCTCTATTTTAATTACTGCT :::::: ::::: :: :::::::::::: :::::: ::::: : : ::: :::::::::: ::: :::::::::: : BTCATH CATTGAGGATCCAAGTTGTGATTTGAATGCTGTGACGATTTTTATAAGGGTAAAATGTTACCACTACTTTAATTACTATT 1200 1210 1220 1230 1240 1250 1260 1270 1480 1490 1500 1510 1520 1530 1540 1550 QUERY ATAAATAGGTTTATATTATTGATTCACTTACTGACTTTGCATTTTCGTTTTTAAAAGGATGTATAAATTTTTACCTGTTT :::::::: :::::: : :::: ::: : :: ::: : : :::: :: : : : :::::: : : BTCATH ATAAATAGCTTTATAATGTTGA-AGACTCATTG-CTTAACTCTAAGACTTTT-----GAATTTTCATTTTTTAAAAG-AT 1280 1290 1300 1310 1320 1330 1340 1560 1570 QUERY AAATAAAA--TTTAATTTCAAATGT : :::::: : ::::: : : BTCATH ATATAAAACTCTGAATTTTACAATAAATTTTAATTCAATACAT 1350 1360 1370 1380 --------------------------------------------------------------------------- >>RNCATHL Y00697 Rat mRNA for cathepsin L (EC 3.4.22.15). 9/93 (1386 nt) initn: 3015 init1: 2903 opt: 3292 Z-score: 2751.5 expect() 1.5e-146 75.423% identity in 1241 nt overlap Entrez lookup Re-search database >RNCATH 274-1505: ------------------------------------------------------- : 240 250 260 270 280 290 300 310 QUERY GACTGGTTGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGT-TTTAAAACATGAATCCTACACTCATCCTTGCT : ::::: ::: :: ::::: ::: :::: :::: ::: RNCATH GATCCGAGTTTGCAGACTACGTGTGTGCGCAGCTAGCCACCTCAGGTGTTTGAACCATGACCCCTTTACTCCTCCTGGCT 30 40 50 60 70 80 90 100 320 330 340 350 360 370 380 390 QUERY GCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGAT : : : ::: :::::: :::: ::: :::: :: ::::::::: : :: : ::::::::: : :::::::: : : RNCATH GTCCTCTGCTTGGGAACAGCCTTAGCCACTCCAAAATTTGATCAAACGTTTAATGCACAGTGGCACCAGTGGAAGTCCAC 110 120 130 140 150 160 170 180 400 410 420 430 440 450 460 470 QUERY GCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGC :::: ::: : :: :::: :::::: :::: ::::::::::::::::::::::::::::::: :::::: : :: : RNCATH ACACAGAAGACTGTATGGCACGAATGAGGAAGAGTGGAGGAGAGCAGTGTGGGAGAAGAACATGAGGATGATCCAGCTAC 190 200 210 220 230 240 250 260 480 490 500 510 520 530 540 550 QUERY ACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTC ::::: ::: ::::: : ::::: ::: :::: :: :::: ::::::::::: :: :::::::::: ::: :::::: RNCATH ACAATGGGGAGTACAGCAACGGGAAGCACGGCTTTACCATGGAGATGAACGCCTTCGGTGACATGACCAATGAGGAATTC 270 280 290 300 310 320 330 340 560 570 580 590 600 610 620 630 QUERY AGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCC :::::: : ::::::::: :: ::: :::: :: :::::: : : :: :::::::::::: : :: ::: RNCATH AGGCAGATAGTGAATGGCTATCGCCACCAGAAGCACAAGAAGGGAAGGTTATTTCAGGAACCTCTGATGCTGCAGATCCC 350 360 370 380 390 400 410 420 640 650 660 670 680 690 700 710 QUERY CAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTA :: ::::::: :::::::: :: :: : ::::::::::::::::::::::: :::::::::::::: :::::::::: RNCATH CAAGACTGTGGACTGGAGAGAAAAGGGTTGTGTGACTCCTGTGAAGAATCAGGGCCAGTGTGGTTCTTGCTGGGCTTTTA 430 440 450 460 470 480 490 500 720 730 740 750 760 770 780 790 QUERY GTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGAC : :: : ::: :: :::::::::::::::: :: ::::: : :: :::::::::::::: ::::: :: :: ::: RNCATH GCGCATCGGGTTGCCTAGAAGGACAGATGTTCCTTAAGACTGGCAAACTGATCTCACTGAGTGAACAGAACCTTGTGGAC 510 520 530 540 550 560 570 580 800 810 820 830 840 850 860 870 QUERY TGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGG :: ::: :::::::::: : ::::: ::::: ::::: ::::::: :::::::::::: :: :::: :::::::: RNCATH TGTTCTCACGATCAAGGCAATCAGGGCTGTAATGGAGGCCTGATGGATTTTGCTTTCCAGTACATTAAGGAAAATGGAGG 590 600 610 620 630 640 650 660 880 890 900 910 920 930 940 950 QUERY CCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATG :::::::: ::::: :: ::::: ::::: :::: :: : ::: ::::: :::: : ::::: :::: ::::: : RNCATH TCTGGACTCAGAGGAGTCTTATCCCTATGAAGCAAAGGATGGATCTTGTAAATACAGAGCTGAGTATGCTGTGGCTAACG 670 680 690 700 710 720 730 740 960 970 980 990 1000 1010 1020 1030 QUERY ACACCGGCTTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCT :::: :: :::::::: :::::: :::: ::::: ::::: :::::: : :: :: :: :::::::: ::::::::::: RNCATH ACACAGGGTTTGTGGATATCCCTCAGCAAGAGAAAGCCCTCATGAAGCCTGTAGCGACGGTGGGGCCTATTTCTGTTGCC 750 760 770 780 790 800 810 820 1040 1050 1060 1070 1080 1090 1100 1110 QUERY ATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGA :: :::::: : ::: ::: ::: :::::::: ::: :: :: : ::: :: :::::::::: : ::: : :: RNCATH ATGGATGCAAGCCATCCGTCTCTCCAGTTCTATAGTTCAGGTATCTACTATGAACCCAACTGTAGCAGCAAGGACCTCGA 830 840 850 860 870 880 890 900 1120 1130 1140 1150 1160 1170 1180 1190 QUERY TCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCT ::::: :: :::::::::::::: :: : :::: : ::::: ::: :::: ::::::: ::::: :: :: ::::::: RNCATH CCATGGGGTTCTGGTGGTTGGCTATGGTTATGAAGGAACAGATTCAAATAAGGATAAATACTGGCTTGTCAAAAACAGCT 910 920 930 940 950 960 970 980 1200 1210 1220 1230 1240 1250 1260 1270 QUERY GGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCC ::::: :::::::::: :::: ::::::: : :: :: ::::::::::::: ::::: :: ::: ::::: : :::::: RNCATH GGGGTAAAGAATGGGGTATGGATGGCTACATCAAAATAGCCAAAGACCGGAACAACCACTGCGGACTTGCCACCGCAGCC 990 1000 1010 1020 1030 1040 1050 1060 1280 1290 1300 1310 1320 1330 1340 1350 QUERY AGCTACCCCACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCAT ::::: :: : :::: :: ::::: : ::: : :::::: :::: ::: ::: : :::: :: : RNCATH AGCTATCCTA--TCGTGAATTGATGGACAGCGAT-AATAAGGAC-TGAC---GGACACTACATCCGAAGGAGTTCATCTT 1070 1080 1090 1100 1110 1120 1130 1360 1370 1380 1390 1400 1410 1420 QUERY -CTTCAGTCTACCAGCCCCCGCTGTGTCGGATACA---CACTCGAATCATTGAAGATCCGAGT-GTGATTTGAATTCTG- : : : : : :: : ::: :: :: :: ::: ::::: :: : ::::: ::: ::::: ::::::: RNCATH AAAACTGACCA-AACCCGTCTCTGAGTGAGA-CCATGGTACTTGAATCGTTCAGGATCCAAGTCACGATTTAAATTCTGT 1140 1150 1160 1170 1180 1190 1200 1210 1430 1440 1450 1460 1470 1480 1490 1500 QUERY TGATATTTTCACACTGG-TAAATGTTACCTCTA-TTTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACTTACT ::: ::::: ::: :: ::::::::::: ::: :: :: : ::: :::::: :: :::::: ::::: :::::: : RNCATH TGACATTTTTACATGGGTTAAATGTTACCACTACTTAAAACTCCTGTTATAAACAGCTTTATAATATTG-GACACTTAAT 1220 1230 1240 1250 1260 1270 1280 1290 1510 1520 1530 1540 1550 1560 1570 QUERY GACTTTGCATTTTCGTTTTTAAAAGGATGTATAAATTTTTACCTGTTTAAATAAAATTTAATTTCAAATGT : RNCATH GCTTAATTCTGATTCTGGAATATTTGTTTTATAAAAGTTGTATAAAACTTTCTTTACCTTTTAAAAATAAATTTTAGCTC 1300 1310 1320 1330 1340 1350 1360 1370 --------------------------------------------------------------------------- >>MUSPROL M20495 Mouse cathepsin L gene, complete cds, clones a-H-ras-1 and R (1413 nt) initn: 3121 init1: 2944 opt: 3195 Z-score: 2670.2 expect() 5e-142 74.496% identity in 1239 nt overlap Entrez lookup Re-search database >MUSPRO 277-1505: ------------------------------------------------------- : 240 250 260 270 280 290 300 310 QUERY TGGTTGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGTTTTAAAACATGAATCCTACACTCATCCTTGCTGCCT ::::::::::::::::::: : :::: : : :::: : MUSPRO AGGATTGGTCTAATCAGATCCTCATTTTTGTTCCCTTCCTAGGTTTTAAAACATGAATCTTTTACTCCTTTTGGCTGTCC 60 70 80 90 100 110 120 130 320 330 340 350 360 370 380 390 QUERY TTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCAC : ::: :::::: :::: :::::::: :: ::::::::: : :: ::: ::::: : :::::::: : : :::: MUSPRO TCTGCTTGGGAACAGCCTTAGCTACTCCAAAATTTGATCAAACCTTTAGTGCAGAGTGGCACCAGTGGAAGTCCACGCAC 140 150 160 170 180 190 200 210 400 410 420 430 440 450 460 470 QUERY AACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAA : ::: : :: :::: :::::: :::: ::::::::::: : :::::::::::::::: :: :: : :: ::::: MUSPRO AGAAGACTGTATGGCACGAATGAGGAAGAGTGGAGGAGAGCGATATGGGAGAAGAACATGAGAATCATCCAGCTACACAA 220 230 240 250 260 270 280 290 480 490 500 510 520 530 540 550 QUERY TCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGC ::::::::: : ::: : ::: :::: : :::: :::::::::::::: :::::::::: ::: :::::::::: MUSPRO CGGGGAATACAGCAACGGGCAGCACGGCTTTTCCATGGAGATGAACGCCTTTGGTGACATGACCAATGAGGAATTCAGGC 300 310 320 330 340 350 360 370 560 570 580 590 600 610 620 630 QUERY AGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA ::::: ::::::::: :: ::: :::: :: :::::::: : :: :::::::: ::: : : :: ::::: MUSPRO AGGTGGTGAATGGCTATCGCCACCAGAAGCACAAGAAGGGGAGGCTTTTTCAGGAACCGCTGATGCTTAAGATCCCCAAG 380 390 400 410 420 430 440 450 640 650 660 670 680 690 700 710 QUERY TCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGC :::::::: :::::::: :: :: : ::::::::::::::::: ::::: ::::: :: ::::::::::: ::::: :: MUSPRO TCTGTGGACTGGAGAGAAAAGGGTTGTGTGACTCCTGTGAAGAACCAGGGCCAGTGCGGGTCTTGTTGGGCGTTTAGCGC 460 470 480 490 500 510 520 530 720 730 740 750 760 770 780 790 QUERY TACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCT : ::: :: :::::::::::::::: :: :: :: : :: :::::::::::::: ::::: :: :: ::::: : MUSPRO ATCGGGTTGCCTAGAAGGACAGATGTTCCTTAAGACCGGCAAACTGATCTCACTGAGTGAACAGAACCTTGTGGACTGTT 540 550 560 570 580 590 600 610 800 810 820 830 840 850 860 870 QUERY CTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTG :: ::::::::::: : ::::: :: :: ::::: ::::::: :::::::::::: :: :::: :::::::: ::: MUSPRO CTCACGCTCAAGGCAATCAGGGCTGTAACGGAGGCCTGATGGATTTTGCTTTCCAGTACATTAAGGAAAATGGAGGTCTG 620 630 640 650 660 670 680 690 880 890 900 910 920 930 940 950 QUERY GACTCTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACAC ::::: ::::: :: :: :: ::::: :::: :: : ::: ::::: :::: :: ::: :::: ::::::::::: MUSPRO GACTCGGAGGAGTCTTACCCCTATGAAGCAAAGGACGGATCTTGTAAATACAGAGCCGAGTTCGCTGTGGCTAATGACAC 700 710 720 730 740 750 760 770 960 970 980 990 1000 1010 1020 1030 QUERY CGGCTTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTG :: :: ::::: :::::: :::: ::::: ::::: :::::::: :: :: ::::::::::: :::::::::::::: : MUSPRO AGGGTTCGTGGATATCCCTCAGCAAGAGAAAGCCCTCATGAAGGCTGTGGCGACTGTGGGGCCTATTTCTGTTGCTATGG 780 790 800 810 820 830 840 850 1040 1050 1060 1070 1080 1090 1100 1110 QUERY ATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCAT : ::: : ::: ::: ::: :::::::: :::::: :: : ::: :: :::::::::: : :: : :: ::: MUSPRO ACGCAAGCCATCCGTCTCTCCAGTTCTATAGTTCAGGCATCTACTATGAACCCAACTGTAGCAGCAAGAACCTCGACCAT 860 870 880 890 900 910 920 930 1120 1130 1140 1150 1160 1170 1180 1190 QUERY GGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGG :: :: ::: :::: ::::: :: : :::: : ::::: ::: :::: :::::::::::::: :: :::::::::::::: MUSPRO GGGGTTCTGTTGGTGGGCTATGGCTATGAAGGAACAGATTCAAATAAGAATAAATATTGGCTTGTCAAGAACAGCTGGGG 940 950 960 970 980 990 1000 1010 1200 1210 1220 1230 1240 1250 1260 1270 QUERY TGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCT :::::::: :::: :::::: : :: :: :::::::::::: ::::: :::::: ::::: : :: ::::::: MUSPRO AAGTGAATGGGGTATGGAAGGCTACATCAAAATAGCCAAAGACCGGGACAACCACTGTGGACTTGCCACCGCGGCCAGCT 1020 1030 1040 1050 1060 1070 1080 1090 1280 1290 1300 1310 1320 1330 1340 1350 QUERY ACCCCACTGT-GTGAGCTGGTGG---ACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCAT : : :::: :::: :: ::: :::: ::::::: : : ::: ::: : : : : :: :: : MUSPRO ATC---CTGTCGTGAATTGATGGGTAGCGGTAATGAGGACTTA-TGGAC--ACTATGTCCAAAGGAATTCAG--CTTAA- 1100 1110 1120 1130 1140 1150 1160 1360 1370 1380 1390 1400 1410 1420 QUERY CTTCAGTCTACCAGCCCCCGCTGTGTCGGA--TACACACTCGAATCATTGAAGATCCGAGT-GTGATTTGAATTCTG-TG : : : : ::: :: ::: : ::: :::::::::: ::::: ::: :::::::::::::: :: MUSPRO ---AACTGACCAAACCCTTATTGAGTCAAACCATGGTACTTGAATCATTGAGGATCCAAGTCATGATTTGAATTCTGTTG 1170 1180 1190 1200 1210 1220 1230 1240 1430 1440 1450 1460 1470 1480 1490 1500 QUERY ATATTTTCACACTGG-TAAATGTTACCTCTA-TTTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACTTACTGA ::::: ::: :: ::::::::::: ::: :: :: : ::: :::::: :: :::::: :::::: ::::: :: MUSPRO CCATTTTTACATGGGTTAAATGTTACCACTACTTAAAACTCCTGTTATAAACAGCTTTATAATATTGA-AAACTTAGTGC 1250 1260 1270 1280 1290 1300 1310 1320 1510 1520 1530 1540 1550 1560 1570 QUERY CTTTGCATTTTCGTTTTTAAAAGGATGTATAAATTTTTACCTGTTTAAATAAAATTTAATTTCAAATGT MUSPRO TTAATTCTGAGTCTGGAATATTTGTTTTATATAAAGGTTGTATAAAACTTTCTTTACCTCTTAAAAATAAATTTTAGCTC 1330 1340 1350 1360 1370 1380 1390 1400 --------------------------------------------------------------------------- >>MMMEPR X06086 Mouse mRNA for major excreted protein (MEP). 3/95 (1374 nt) initn: 3075 init1: 2898 opt: 3168 Z-score: 2647.7 expect() 9.1e-141 74.217% identity in 1245 nt overlap Entrez lookup Re-search database >MMMEPR 272-1505: ------------------------------------------------------- : 240 250 260 270 280 290 300 310 QUERY GTGACTGGTTGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGT-TTTAAAACATGAATCCTACACTCATCCTTG : : ::::: ::: :: :::::::: : :::: : : : MMMEPR CGGGGATCCGAGTTTGCAGACTTCTTGTGCGCACGTAGCCGCCTCAGGTGTTTGAACCATGAATCTTTTACTCCTTTTGG 20 30 40 50 60 70 80 90 320 330 340 350 360 370 380 390 QUERY CTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCG ::: : : ::: :::::: :::: :::::::: :: ::::::::: : :: ::: ::::: : :::::::: : MMMEPR CTGTCCTCTGCTTGGGAACAGCCTTAGCTACTCCAAAATTTGATCAAACCTTTAGTGCAGAGTGGCACCAGTGGAAGTCC 100 110 120 130 140 150 160 170 400 410 420 430 440 450 460 470 QUERY ATGCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACT : ::::: ::: : :: :::: :::::: :::: ::::::::::: : :::::::::::::::: ::::: : :: MMMEPR ACGCACAGAAGACTGTATGGCACGAATGAGGAAGAGTGGAGGAGAGCGATATGGGAGAAGAACATGAGAATGATCCAGCT 180 190 200 210 220 230 240 250 480 490 500 510 520 530 540 550 QUERY GCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAAT ::::: ::::::::: : ::: : ::: :::: : :::: :::::::::::::: :::::::::: ::: :::: MMMEPR ACACAACGGGGAATACAGCAACGGGCAGCACGGCTTTTCCATGGAGATGAACGCCTTTGGTGACATGACCAATGAGGAAT 260 270 280 290 300 310 320 330 560 570 580 590 600 610 620 630 QUERY TCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCC ::::::::::: ::::::::: :: ::: :::: :: :::::::: : :: :::::::: ::: : : :: : MMMEPR TCAGGCAGGTGGTGAATGGCTATCGCCACCAGAAGCACAAGAAGGGGAGGCTTTTTCAGGAACCGCTGATGCTTAAGATC 340 350 360 370 380 390 400 410 640 650 660 670 680 690 700 710 QUERY CCCAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTT :::: :::::::: :::::::: :: :: : ::::::::::::::::: ::::: ::::: :: ::::::::::: :: MMMEPR CCCAAGTCTGTGGACTGGAGAGAAAAGGGTTGTGTGACTCCTGTGAAGAACCAGGGCCAGTGCGGGTCTTGTTGGGCGTT 420 430 440 450 460 470 480 490 720 730 740 750 760 770 780 790 QUERY TAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAG ::: :: : ::: :: :::::::::::::::: :: :: :: : :: :::::::::::::: ::::: :: :: : MMMEPR TAGCGCATCGGGTTGCCTAGAAGGACAGATGTTCCTTAAGACCGGCAAACTGATCTCACTGAGTGAACAGAACCTTGTGG 500 510 520 530 540 550 560 570 800 810 820 830 840 850 860 870 QUERY ACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGA :::: ::: ::::::::::: : ::::: :: :: ::::: ::::::: :::::::::::: :: :::: :::::: MMMEPR ACTGTTCTCACGCTCAAGGCAATCAGGGCTGTAACGGAGGCCTGATGGATTTTGCTTTCCAGTACATTAAGGAAAATGGA 580 590 600 610 620 630 640 650 880 890 900 910 920 930 940 950 QUERY GGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAA :: :::::::: ::::: :: :: :: ::::: :::: :: : ::: ::::: :::: :: ::: :::: ::::: MMMEPR GGTCTGGACTCGGAGGAGTCTTACCCCTATGAAGCAAAGGACGGATCTTGTAAATACAGAGCCGAGTTCGCTGTGGCTAA 660 670 680 690 700 710 720 730 960 970 980 990 1000 1010 1020 1030 QUERY TGACACCGGCTTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTG :::::: :: :: ::::: :::::: :::: ::::: ::::: :::::::: :: :: ::::::::::: :::::::::: MMMEPR TGACACAGGGTTCGTGGATATCCCTCAGCAAGAGAAAGCCCTCATGAAGGCTGTGGCGACTGTGGGGCCTATTTCTGTTG 740 750 760 770 780 790 800 810 1040 1050 1060 1070 1080 1090 1100 1110 QUERY CTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATG :::: :: ::: : ::: ::: ::: :::::::: :::::: :: : ::: :: :::::::::: : :: : MMMEPR CTATGGACGCAAGCCATCCGTCTCTCCAGTTCTATAGTTCAGGCATCTACTATGAACCCAACTGTAGCAGCAAGAACCTC 820 830 840 850 860 870 880 890 1120 1130 1140 1150 1160 1170 1180 1190 QUERY GATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAG :: ::::: :: ::: :::: ::::: :: : :::: : ::::: ::: :::: :::::::::::::: :: :::::::: MMMEPR GACCATGGGGTTCTGTTGGTGGGCTATGGCTATGAAGGAACAGATTCAAATAAGAATAAATATTGGCTTGTCAAGAACAG 900 910 920 930 940 950 960 970 1200 1210 1220 1230 1240 1250 1260 1270 QUERY CTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAG :::::: :::::::: :::: :::::: : :: :: :::::::::::: ::::: :::::: ::::: : :: : MMMEPR CTGGGGAAGTGAATGGGGTATGGAAGGCTACATCAAAATAGCCAAAGACCGGGACAACCACTGTGGACTTGCCACCGCGG 980 990 1000 1010 1020 1030 1040 1050 1280 1290 1300 1310 1320 1330 1340 QUERY CCAGCTACCCCACTGT-GTGAGCTGGTGG---ACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGA ::::::: : :::: :::: :: ::: :::: ::::::: : : ::: ::: : : : : :: MMMEPR CCAGCTATC---CTGTCGTGAATTGATGGGTAGCGGTAATGAGGACTTA-TGGAC--ACTATGTCCAAAGGAATTCAG-- 1060 1070 1080 1090 1100 1110 1120 1350 1360 1370 1380 1390 1400 1410 1420 QUERY ATTCATCTTCAGTCTACCAGCCCCCGCTGTGTCGGA--TACACACTCGAATCATTGAAGATCCGAGT-GTGATTTGAATT :: : : : : : ::: :: ::: : ::: :::::::::: ::::: ::: ::::::::::: MMMEPR CTTAA----AACTGACCAAACCCTTATTGAGTCAAACCATGGTACTTGAATCATTGAGGATCCAAGTCATGATTTGAATT 1130 1140 1150 1160 1170 1180 1190 1430 1440 1450 1460 1470 1480 1490 1500 QUERY CTG-TGATATTTTCACACTGG-TAAATGTTACCTCTA-TTTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACT ::: : ::::: ::: :: ::::::::::: ::: :: :: : ::: :::::: :: :::::: :::::: ::: MMMEPR CTGTTCCCATTTTTACATGGGTTAAATGTTACCACTACTTAAAACTCCTGTTATAAACAGCTTTATAATATTGA-AAACT 1200 1210 1220 1230 1240 1250 1260 1270 1510 1520 1530 1540 1550 1560 1570 QUERY TACTGACTTTGCATTTTCGTTTTTAAAAGGATGTATAAATTTTTACCTGTTTAAATAAAATTTAATTTCAAATGT :: :: MMMEPR TAGTGCTTAATTCTGAGTCTGGAATATTTGTTTTATATAAAGGTTGTATAAAACTTTCTTTACCTCTTAAAAATAAATTT 1280 1290 1300 1310 1320 1330 1340 1350 --------------------------------------------------------------------------- >>MUSCPR J02583 Mouse cysteine proteinase mRNA, complete cds. 6/93 (1276 nt) initn: 3021 init1: 2898 opt: 3168 Z-score: 2648.2 expect() 9.2e-141 74.217% identity in 1245 nt overlap Entrez lookup Re-search database >MUSCPR 272-1505: -------------------------------------------------------: 240 250 260 270 280 290 300 310 QUERY GTGACTGGTTGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGT-TTTAAAACATGAATCCTACACTCATCCTTG : : ::::: ::: :: :::::::: : :::: : : : MUSCPR CCGGGGATCCGAGTTTGCAGACTTCTTGTGCGCACTAGCCGCCTCAGGTGTTTGAACCATGAATCTTTTACTCCTTTTGG 10 20 30 40 50 60 70 80 320 330 340 350 360 370 380 390 QUERY CTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCG ::: : : ::: :::::: :::: :::::::: :: ::::::::: : :: ::: ::::: : :::::::: : MUSCPR CTGTCCTCTGCTTGGGAACAGCCTTAGCTACTCCAAAATTTGATCAAACCTTTAGTGCAGAGTGGCACCAGTGGAAGTCC 90 100 110 120 130 140 150 160 400 410 420 430 440 450 460 470 QUERY ATGCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACT : ::::: ::: : :: :::: :::::: :::: ::::::::::: : :::::::::::::::: ::::: : :: MUSCPR ACGCACAGAAGACTGTATGGCACGAATGAGGAAGAGTGGAGGAGAGCGATATGGGAGAAGAACATGAGAATGATCCAGCT 170 180 190 200 210 220 230 240 480 490 500 510 520 530 540 550 QUERY GCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAAT ::::: ::::::::: : ::: : ::: :::: : :::: :::::::::::::: :::::::::: ::: :::: MUSCPR ACACAACGGGGAATACAGCAACGGGCAGCACGGCTTTTCCATGGAGATGAACGCCTTTGGTGACATGACCAATGAGGAAT 250 260 270 280 290 300 310 320 560 570 580 590 600 610 620 630 QUERY TCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCC ::::::::::: ::::::::: :: ::: :::: :: :::::::: : :: :::::::: ::: : : :: : MUSCPR TCAGGCAGGTGGTGAATGGCTATCGCCACCAGAAGCACAAGAAGGGGAGGCTTTTTCAGGAACCGCTGATGCTTAAGATC 330 340 350 360 370 380 390 400 640 650 660 670 680 690 700 710 QUERY CCCAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTT :::: :::::::: :::::::: :: :: : ::::::::::::::::: ::::: ::::: :: ::::::::::: :: MUSCPR CCCAAGTCTGTGGACTGGAGAGAAAAGGGTTGTGTGACTCCTGTGAAGAACCAGGGCCAGTGCGGGTCTTGTTGGGCGTT 410 420 430 440 450 460 470 480 720 730 740 750 760 770 780 790 QUERY TAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAG ::: :: : ::: :: :::::::::::::::: :: :: :: : :: :::::::::::::: ::::: :: :: : MUSCPR TAGCGCATCGGGTTGCCTAGAAGGACAGATGTTCCTTAAGACCGGCAAACTGATCTCACTGAGTGAACAGAACCTTGTGG 490 500 510 520 530 540 550 560 800 810 820 830 840 850 860 870 QUERY ACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGA :::: ::: ::::::::::: : ::::: :: :: ::::: ::::::: :::::::::::: :: :::: :::::: MUSCPR ACTGTTCTCACGCTCAAGGCAATCAGGGCTGTAACGGAGGCCTGATGGATTTTGCTTTCCAGTACATTAAGGAAAATGGA 570 580 590 600 610 620 630 640 880 890 900 910 920 930 940 950 QUERY GGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAA :: :::::::: ::::: :: :: :: ::::: :::: :: : ::: ::::: :::: :: ::: :::: ::::: MUSCPR GGTCTGGACTCGGAGGAGTCTTACCCCTATGAAGCAAAGGACGGATCTTGTAAATACAGAGCCGAGTTCGCTGTGGCTAA 650 660 670 680 690 700 710 720 960 970 980 990 1000 1010 1020 1030 QUERY TGACACCGGCTTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTG :::::: :: :: ::::: :::::: :::: ::::: ::::: :::::::: :: :: ::::::::::: :::::::::: MUSCPR TGACACAGGGTTCGTGGATATCCCTCAGCAAGAGAAAGCCCTCATGAAGGCTGTGGCGACTGTGGGGCCTATTTCTGTTG 730 740 750 760 770 780 790 800 1040 1050 1060 1070 1080 1090 1100 1110 QUERY CTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATG :::: :: ::: : ::: ::: ::: :::::::: :::::: :: : ::: :: :::::::::: : :: : MUSCPR CTATGGACGCAAGCCATCCGTCTCTCCAGTTCTATAGTTCAGGCATCTACTATGAACCCAACTGTAGCAGCAAGAACCTC 810 820 830 840 850 860 870 880 1120 1130 1140 1150 1160 1170 1180 1190 QUERY GATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAG :: ::::: :: ::: :::: ::::: :: : :::: : ::::: ::: :::: :::::::::::::: :: :::::::: MUSCPR GACCATGGGGTTCTGTTGGTGGGCTATGGCTATGAAGGAACAGATTCAAATAAGAATAAATATTGGCTTGTCAAGAACAG 890 900 910 920 930 940 950 960 1200 1210 1220 1230 1240 1250 1260 1270 QUERY CTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAG :::::: :::::::: :::: :::::: : :: :: :::::::::::: ::::: :::::: ::::: : :: : MUSCPR CTGGGGAAGTGAATGGGGTATGGAAGGCTACATCAAAATAGCCAAAGACCGGGACAACCACTGTGGACTTGCCACCGCGG 970 980 990 1000 1010 1020 1030 1040 1280 1290 1300 1310 1320 1330 1340 QUERY CCAGCTACCCCACTGT-GTGAGCTGGTGG---ACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGA ::::::: : :::: :::: :: ::: :::: ::::::: : : ::: ::: : : : : :: MUSCPR CCAGCTATC---CTGTCGTGAATTGATGGGTAGCGGTAATGAGGACTTA-TGGAC--ACTATGTCCAAAGGAATTCAG-- 1050 1060 1070 1080 1090 1100 1110 1350 1360 1370 1380 1390 1400 1410 1420 QUERY ATTCATCTTCAGTCTACCAGCCCCCGCTGTGTCGGA--TACACACTCGAATCATTGAAGATCCGAGT-GTGATTTGAATT :: : : : : : ::: :: ::: : ::: :::::::::: ::::: ::: ::::::::::: MUSCPR CTTAA----AACTGACCAAACCCTTATTGAGTCAAACCATGGTACTTGAATCATTGAGGATCCAAGTCATGATTTGAATT 1120 1130 1140 1150 1160 1170 1180 1430 1440 1450 1460 1470 1480 1490 1500 QUERY CTG-TGATATTTTCACACTGG-TAAATGTTACCTCTA-TTTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACT ::: : ::::: ::: :: ::::::::::: ::: :: :: : ::: :::::: :: :::::: :::::: ::: MUSCPR CTGTTCCCATTTTTACATGGGTTAAATGTTACCACTACTTAAAACTCCTGTTATAAACAGCTTTATAATATTGA-AAACT 1190 1200 1210 1220 1230 1240 1250 1260 1510 1520 1530 1540 1550 1560 1570 QUERY TACTGACTTTGCATTTTCGTTTTTAAAAGGATGTATAAATTTTTACCTGTTTAAATAAAATTTAATTTCAAATGT :: :: MUSCPR TAGTGCTT 1270 --------------------------------------------------------------------------- >>RNU16858 U16858 Rattus norvegicus testin mRNA, complete cds. 2/95 (1371 nt) initn: 2511 init1: 2401 opt: 2586 Z-score: 2160.5 expect() 1.3e-113 71.364% identity in 1107 nt overlap Entrez lookup Re-search database >RNU168 274-1377: ------------------------------------------------- : 240 250 260 270 280 290 300 310 QUERY GACTGGTTGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGT-TTTAAAACATGAATCCTACACTCATCCTTGCT : ::::: : : : :::::: : :: ::: :::: :: RNU168 AACTCAAGTCTGAGGAGATCATCTGAGGAGCAGCAGACATCCCAGGTGTATGAGACATGATTGCTGTTCTCTTCCTAGCG 50 60 70 80 90 100 110 120 320 330 340 350 360 370 380 390 QUERY GCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGAT : ::: ::: : ::: :::: :: ::: :::: :::: :::::: :: : :::::: : :::: : : : RNU168 ATTCTCTGCTTGGAAGTTGACTCAACTGCTCCAACACCAGATCCCAGTTTGGATGTTGAGTGGAATGAATGGAGGACAAA 130 140 150 160 170 180 190 200 400 410 420 430 440 450 460 470 QUERY GCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGC :: : : :::: ::::::::::::: :: :: :::::: :::::::: ::::: : :: ::::::::::::: RNU168 ACATGGGAAAACATACAACATGAATGAAGAAAGACTGAAGAGAGCTGTGTGGGAAAAGAATTTTAAAATGATTGAACTGC 210 220 230 240 250 260 270 280 480 490 500 510 520 530 540 550 QUERY ACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTC : ::: ::::::: :: :::: :: :::::: ::::: ::::: :::::::: ::: :::::: : :::::: RNU168 ATAATTGGGAATACCTTGAGGGGAGGCATGACTTCACCATGGCAATGAATGCCTTTGGTGACTTGACCAATATAGAATTT 290 300 310 320 330 340 350 360 560 570 580 590 600 610 620 630 QUERY AGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCC : : :::::: :::::::::: : ::: :: :::: : : : :::::::: : :: :::: : : : ::: RNU168 GTGAAAATGATGACAGGCTTTCAAAGGCAGAAGATCAAGAAGACGCACATATTCCAGGATCATCAGTTTCTTTATGTCCC 370 380 390 400 410 420 430 440 640 650 660 670 680 690 700 710 QUERY CAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTA : : ::::::::::::: : ::::: :::::::::::::::::::::::::: :::: ::: :::::::::::: RNU168 AAAACGTGTGGATTGGAGACAACTTGGCTATGTGACTCCTGTGAAGAATCAGGGTCATTGTGCCTCTAGTTGGGCTTTTA 450 460 470 480 490 500 510 520 720 730 740 750 760 770 780 790 QUERY GTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGAC :::: ::::: : :: :::::::: :::::: ::::::: : :: :: ::: : :::::::::::::: :: : ::: RNU168 GTGCAACTGGGTCCCTAGAAGGACAAATGTTCAGGAAAACAGAAAGACTGATCCCTCTGAGTGAGCAGAACCTACTGGAC 530 540 550 560 570 580 590 600 800 810 820 830 840 850 860 870 QUERY TGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGG ::: :: :: : : : : :: :::: :::::: : ::: : ::::: ::::: :: :: : :: ::::: :: RNU168 TGCATGGGATCTAATGTTACCCATGGTTGCAGCGGTGGCTTCATGCAGTATGCCTTCCAATACGTGAAAGACAATGGCGG 610 620 630 640 650 660 670 680 880 890 900 910 920 930 940 950 QUERY CCTGGACTCTGAGGAATCCTATCCATA-TGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAAT ::: : :::::::::::::::: :: :::: : : :: : :: : :::: : : :: :::::: :::::: RNU168 CCTTGCAACTGAGGAATCCTATCCTTACAGAGGACAAGGTAG-AGAGTGCAGGTACCACGCTGAGAATTCTGCGGCTAAT 690 700 710 720 730 740 750 960 970 980 990 1000 1010 1020 1030 QUERY GACACCGGCTTTGTGGACATCCCTAAGCAG-GAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTG : :: : :::::: : ::::: : : :: ::: : ::::: ::::::::::: :: : ::::::::::: ::::::: RNU168 GTCAGAGATTTTGTGCAAATCCC-AGGAAGCGAGGAAGCCCTTATGAAGGCAGTGGCTAAAGTGGGGCCCATCTCTGTTG 760 770 780 790 800 810 820 830 1040 1050 1060 1070 1080 1090 1100 1110 QUERY CTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATG : ::::::: : :::: ::::::: :::::: ::::: :::: ::::::: : :::: :: : :: : RNU168 CAGTTGATGCCAGCCATGGTTCCTTCCAGTTCTACGGTAGTGGCATCTATTATGAGCCACAGTGTAAAAGGGTTCACCTA 840 850 860 870 880 890 900 910 1120 1130 1140 1150 1160 1170 1180 1190 QUERY GATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAG :::::: ::: :: ::::: ::::: :: :::::: : :::::::::: ::: : : :::::: :: :::::::: RNU168 AATCATGCTGTTCTAGTGGTCGGCTATGGCTTTGAAGGAGAAGAATCAGATGGCAACAGTTTTTGGCTCGTCAAGAACAG 920 930 940 950 960 970 980 990 1200 1210 1220 1230 1240 1250 1260 1270 QUERY CTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAG ::::::::: :::::::::::: :::::: : ::: : ::::::::: :::: ::::: :: :: ::::: :: RNU168 CTGGGGTGAGGAATGGGGCATGAAGGGCTACATGAAGCTTGCCAAAGACTGGAGCAACCACTGCGGGATTGCTACATATT 1000 1010 1020 1030 1040 1050 1060 1070 1280 1290 1300 1310 1320 1330 1340 1350 QUERY CCAGCTACCCCACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTC ::: ::::::: ::: :::::: :: :: :::: ::: :::: : :::: :: ::: : : :: : : ::: RNU168 CCACATACCCCATTGTATGAGCTACTGCACAGTGACAAGGCAGGAGTGGACT-GGAATG-----TAC-TGAGCAGTTTTC 1080 1090 1100 1110 1120 1130 1140 1150 1360 1370 1380 1390 1400 1410 1420 1430 QUERY ATCTTCAGTCTACCAGCCCCCGCTGTGTCGGATACACACTCGAATCATTGAAGATCCGAGTGTGATTTGAATTCTGTGAT :::: ::::::: : :::::: RNU168 TCCTTCCACAGACCAGCCTCTGCTGTGGGGCAAAGGGGACAGGGGTAGTGACAGCTGAGTCACTGAGGATCCACACCTGA 1160 1170 1180 1190 1200 1210 1220 1230 --------------------------------------------------------------------------- >>S85184 Cyclic Protein-2=cathepsin L proenzyme [rats, Sertoli cells, mRNA, (1790 nt) initn: 2340 init1: 2228 opt: 2505 Z-score: 2090.9 expect() 7.2e-110 75.052% identity in 966 nt overlap Entrez lookup Re-search database >S85184 548-1505: ------------------------------------------- : 510 520 530 540 550 560 570 580 QUERY ACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCC ::::::::::: : ::::::::: :: ::: :::: S85184 AATTCAGGCAGATAGTGAATGGCTATCGCCACCAGAAGCA 10 20 30 40 590 600 610 620 630 640 650 660 QUERY CAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGA :: :::::: : : :: :::::::::::: : :: ::::: ::::::: :::::::: :: :: : :::: S85184 CAAGAAGGGAAGGTTATTTCAGGAACCTCTGATGCTGCAGATCCCCAAGACTGTGGACTGGAGAGAAAAGGGTTGTGTGA 50 60 70 80 90 100 110 120 670 680 690 700 710 720 730 740 QUERY CTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGG ::::::::::::::::::: :::::::::::::: ::::::::::: :: : ::: :: :::::::::::::::: S85184 CTCCTGTGAAGAATCAGGGCCAGTGTGGTTCTTGCTGGGCTTTTAGCGCATCGGGTTGCCTAGAAGGACAGATGTTCCTT 130 140 150 160 170 180 190 200 750 760 770 780 790 800 810 820 QUERY AAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGG :: ::::: : :: :::::::::::::: ::::: :: :: ::::: ::: :::::::::: : ::::: ::::: S85184 AAGACTGGCAAACTGATCTCACTGAGTGAACAGAACCTTGTGGACTGTTCTCACGATCAAGGCAATCAGGGCTGTAATGG 210 220 230 240 250 260 270 280 830 840 850 860 870 880 890 900 QUERY TGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAA ::::: ::::::: :::::::::::: :: :::: :::::::: :::::::: ::::: :: ::::: ::::: :::: S85184 AGGCCTGATGGATTTTGCTTTCCAGTACATTAAGGAAAATGGAGGTCTGGACTCAGAGGAGTCTTATCCCTATGAAGCAA 290 300 310 320 330 340 350 360 910 920 930 940 950 960 970 980 QUERY CAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTAAGCAGGAGAAG :: : ::: ::::: :::: : ::::: :::: ::::: ::::: :: :::::::: :::::: :::: ::::: S85184 AGGATGGATCTTGTAAATACAGAGCTGAGTATGCTGTGGCTAACGACACAGGGTTTGTGGATATCCCTCAGCAAGAGAAA 370 380 390 400 410 420 430 440 990 1000 1010 1020 1030 1040 1050 1060 QUERY GCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAA ::::: :::::::: :: :: :: :::::::: ::::::::::: :: :::::: : ::: ::: ::: :::::::: S85184 GCCCTCATGAAGGCTGTAGCGACGGTGGGGCCTATTTCTGTTGCCATGGATGCAAGCCATCCGTCTCTCCAGTTCTATAG 450 460 470 480 490 500 510 520 1070 1080 1090 1100 1110 1120 1130 1140 QUERY AGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAA ::: :: :: : ::: :: :::::::::: : ::: : :: ::::: :: :::::::::::::: :: : :::: S85184 TTCAGGTATCTACTATGAACCCAACTGTAGCAGCAAGGACCTCGACCATGGGGTTCTGGTGGTTGGCTATGGTTATGAAG 530 540 550 560 570 580 590 600 1150 1160 1170 1180 1190 1200 1210 1220 QUERY GCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAG : ::::: ::: :::: ::::::: ::::: :: :: :::::::::::: :::::::::: :::: ::::::: : :: S85184 GAACAGATTCAAATAAGGATAAATACTGGCTTGTCAAAAACAGCTGGGGTAAAGAATGGGGTATGGATGGCTACATCAAA 610 620 630 640 650 660 670 680 1230 1240 1250 1260 1270 1280 1290 1300 QUERY ATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGACGGTGATG :: ::::::::::::: ::::: :: ::: ::::: : ::::::::::: :: : :::: :: ::::: : ::: S85184 ATAGCCAAAGACCGGAACAACCACTGCGGACTTGCCACCGCAGCCAGCTATCCTA--TCGTGAATTGATGGACAGCGAT- 690 700 710 720 730 740 750 1310 1320 1330 1340 1350 1360 1370 1380 QUERY AGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCAT-CTTCAGTCTACCAGCCCCCGCTGTGTCGGATACA : :::::::: :: ::: ::: : :::: :: : : : : : : :: : ::: :: :: :: S85184 AATAAGGACTT-AC---GGACACTACATCCGAAGGAGTTCATCTTAAAACTGACCA-AACCCGTCTCTGAGTGAGA-CCA 760 770 780 790 800 810 820 830 1390 1400 1410 1420 1430 1440 1450 QUERY ---CACTCGAATCATTGAAGATCCGAGT-GTGATTTGAATTCTG-TGATATTTTCACACTGG-TAAATGTTACCTCTA-T ::: ::::: :: : ::::: ::: ::::: ::::::: ::: ::::: ::: :: ::::::::::: ::: : S85184 TGGTACTTGAATCGTTCAGGATCCAAGTCACGATTTAAATTCTGTTGACATTTTTACATGGGTTAAATGTTACCACTACT 840 850 860 870 880 890 900 910 1460 1470 1480 1490 1500 1510 1520 1530 QUERY TTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACTTACTGACTTTGCATTTTCGTTTTTAAAAGGATGTATAAA : :: : ::: :::::: :: :::::: ::::: :::::: :: S85184 TAAAACTCCTGTTATAAACAGCTTTATAATATTG-GACACTTAATGCTTAATTCTGATTCTGGAATATTTGTTTTATAAA 920 930 940 950 960 970 980 990 1540 1550 1560 1570 QUERY TTTTTACCTGTTTAAATAAAATTTAATTTCAAATGT S85184 AGTTGTATAAAACTTTCTTTACCTTTTAAAAATAAATTTTAGCTCAGTGCATGTGTGTGTGTATGGGTTAGGGGAACTTC 1000 1010 1020 1030 1040 1050 1060 1070 --------------------------------------------------------------------------- >>MMMEPR1 X04392 Mouse mRNA fragment for major excreted protein (MEP). 8/95 (638 nt) initn: 1894 init1: 1894 opt: 1894 Z-score: 1586.1 expect() 2.7e-81 77.429% identity in 638 nt overlap Entrez lookup Re-search database >MMMEPR 553-1190: ----------------------------: 520 530 540 550 560 570 580 590 QUERY GGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGA ::::::::: ::::::::: :: ::: :::: :: :: MMMEPR AGGCAGGTGGTGAATGGCTATCGCCACCAGAAGCACAAGA 10 20 30 40 600 610 620 630 640 650 660 670 QUERY AGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCT :::::: : :: :::::::: ::: : : :: ::::: :::::::: :::::::: :: :: : ::::::::: MMMEPR AGGGGAGGCTTTTTCAGGAACCGCTGATGCTTAAGATCCCCAAGTCTGTGGACTGGAGAGAAAAGGGTTGTGTGACTCCT 50 60 70 80 90 100 110 120 680 690 700 710 720 730 740 750 QUERY GTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAAC :::::::: ::::: ::::: :: ::::::::::: ::::: :: : ::: :: :::::::::::::::: :: :: MMMEPR GTGAAGAACCAGGGCCAGTGCGGGTCTTGTTGGGCGTTTAGCGCATCGGGTTGCCTAGAAGGACAGATGTTCCTTAAGAC 130 140 150 160 170 180 190 200 760 770 780 790 800 810 820 830 QUERY TGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCC :: : :: :::::::::::::: ::::: :: :: ::::: ::: ::::::::::: : ::::: :: :: :::: MMMEPR CGGCAAACTGATCTCACTGAGTGAACAGAACCTTGTGGACTGTTCTCACGCTCAAGGCAATCAGGGCTGTAACGGAGGCC 210 220 230 240 250 260 270 280 840 850 860 870 880 890 900 910 QUERY TAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAGAA : ::::::: :::::::::::: :: :::: :::::::: :::::::: ::::: :: :: :: ::::: :::: :: MMMEPR TGATGGATTTTGCTTTCCAGTACATTAAGGAAAATGGAGGTCTGGACTCGGAGGAGTCTTACCCCTATGAAGCAAAGGAC 290 300 310 320 330 340 350 360 920 930 940 950 960 970 980 990 QUERY GAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTAAGCAGGAGAAGGCCCT : ::: ::::: :::: :: ::: :::: ::::::::::: :: :: ::::: :::::: :::: ::::: ::::: MMMEPR GGATCTTGTAAATACAGAGCCGAGTTCGCTGTGGCTAATGACACAGGGTTCGTGGATATCCCTCAGCAAGAGAAAGCCCT 370 380 390 400 410 420 430 440 1000 1010 1020 1030 1040 1050 1060 1070 QUERY GATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAG :::::::: :: :: ::::::::::: :::::::::::::: :: ::: : ::: ::: ::: :::::::: :: MMMEPR CATGAAGGCTGTGGCGACTGTGGGGCCTATTTCTGTTGCTATGGACGCAAGCCATCCGTCTCTCCAGTTCTATAGTTCAG 450 460 470 480 490 500 510 520 1080 1090 1100 1110 1120 1130 1140 1150 QUERY GCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCACA :::: :: : ::: :: :::::::::: : :: : :: ::::: :: ::: :::: ::::: :: : :::: : ::: MMMEPR GCATCTACTATGAACCCAACTGTAGCAGCAAGAACCTCGACCATGGGGTTCTGTTGGTGGGCTATGGCTATGAAGGAACA 530 540 550 560 570 580 590 600 1160 1170 1180 1190 1200 1210 1220 1230 QUERY GAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGC :: ::: :::: :::::::::::::: :: :::::::: MMMEPR GATTCAAATAAGAATAAATATTGGCTTGTCAAGAACAG 610 620 630 --------------------------------------------------------------------------- >>RATCATLR L14776 Rattus norvegicus cathepsin-related protein mRNA, 3' end. 7 (911 nt) initn: 1461 init1: 1049 opt: 1555 Z-score: 1300.0 expect() 1.6e-65 67.107% identity in 833 nt overlap Entrez lookup Re-search database >RATCAT 599-1422: ------------------------------------ : 560 570 580 590 600 610 620 630 QUERY GTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATC ::::: :::: ::: : : : :: :::: : RATCAT CTAATCCGGCTGCTGTGACAAACCCAAGTG-CCCAGAAACAAGTCTCTATTGGTTTACCCAACTT 10 20 30 40 50 60 640 650 660 670 680 690 700 710 QUERY TGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTA : :::::::::: :: ::::::: ::::::::::: :::::::::: : :: :: ::::::::::::::: ::: RATCAT TAAGGATTGGAGAAAGGAAGGCTATGTGACTCCTGTACGGAATCAGGGTAAATGCGGCTCTTGTTGGGCTTTTGCTGCAG 70 80 90 100 110 120 130 140 720 730 740 750 760 770 780 790 QUERY CTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCT :::::: : ::::: ::::::: : :::::::: : :: : : : :: :::: ::::::::: : :: : :: RATCAT TTGGTGCGATAGAAGGTCAGATGTCTCTCAAAACTGGCAACCTCACCCCTCTAAGTGCGCAGAATCTATTGGA---CACT 150 160 170 180 190 200 210 220 800 810 820 830 840 850 860 870 QUERY GGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGA : :::: ::: : :::::: ::: : :: : : :: ::: : :::::: : : ::: ::: :: :: RATCAT AAAAGTGAAGG-AAT-AGGGCTGCCGTGGGGTACT-GCACACCAAGCATTCAATTATGTTTTGAAAAATAAAGGTCTTGA 230 240 250 260 270 280 290 880 890 900 910 920 930 940 950 QUERY CTCTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCG :::::: : ::::::::::::: : :: ::: : : :::: : :::: : :: : :: :::::: ::: : RATCAT GGCTGAGGCAACCTATCCATATGAAGGAAAAGACGGACCCTGCAGGTACCACAGTGAGAACGCTAGTGCTAACATCACAG 300 310 320 330 340 350 360 370 960 970 980 990 1000 1010 1020 1030 QUERY GCTTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGAT : :::::: :: :::: : : ::: ::: : :: :: ::: :: : :::::: : :::: :: :::::: RATCAT GTTTTGTGAACCTCCCACCGAATGAGCTTTACCTATGGGTTGCTGTAGCATCTATTGGGCCCGTCTCTGCGGCAATTGAT 380 390 400 410 420 430 440 450 1040 1050 1060 1070 1080 1090 1100 1110 QUERY GCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGG :: :::::: :: ::: ::::: : : ::: ::::: ::::::: : :: :::::: : : :: :::::: RATCAT GCTTCTCATGACTCTTTCAGATTCTACAGTGGAGGTGTTTATCATGAGCCAAATTGCAGCAGTTATGTTGTGAATCATGC 460 470 480 490 500 510 520 530 1120 1130 1140 1150 1160 1170 1180 1190 QUERY TGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTG :::::::::::::::::::::::::: : : ::: ::::: :::::: :: :::::: : :::::::: ::::::: RATCAT AGTGCTGGTGGTTGGCTACGGATTTGAGGGAAATGAAACAGATGGCAATAACTACTGGCTGATCAAGAACAGTTGGGGTG 540 550 560 570 580 590 600 610 1200 1210 1220 1230 1240 1250 1260 1270 QUERY AAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTAC ::::::::::::: ::::: : : ::::: :::::::: :: : ::::: ::::::::::: ::: :::::::: : RATCAT AAGAATGGGGCATTAATGGCTTCATGAAGATAGCCAAAGATCGCAACAACCACTGTGGAATTGCTTCACAAGCCAGCTTC 620 630 640 650 660 670 680 690 1280 1290 1300 1310 1320 1330 1340 1350 QUERY CCC---ACTGTGTGAGCTGGTGGACGGTGA--TGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATC ::: : : ::::::: : ::: : ::: ::::: :: ::: :: :: :::: : ::: : RATCAT CCCGATATATTCTGAGCTGCCTGTTGGTCACCACAGGGAGGACATG-GTGGAGA-----CA-GCATTTAGTGCCTTCCAC 700 710 720 730 740 750 760 770 1360 1370 1380 1390 1400 1410 1420 QUERY TTCAGTCT-ACCAGCCCCCGCTGTGTCGGATACACACTCGAATCATTGAAGA---TCCGAGTGTGATTTGAATTCTGTGA :::: : ::::: : : ::: :: : ::: : :: : : :: : :: :::: : :::: RATCAT TTCACAGTAACCAGTCTCTCCTGAGTGCTTTCAACAGTTGAGTAGCTAAAAAGCTACCTTGTGTTGGTGGAATCTGGAAC 780 790 800 810 820 830 840 850 1430 1440 1450 1460 1470 1480 1490 1500 QUERY TATTTTCACACTGGTAAATGTTACCTCTATTTTAATTACTGCTATAAATAGGTTTATATTATTGATTCACTTACTGACTT RATCAT CCACTTGTTCTACAACAGCATGGCAACTACTGTAATAAAATCTGTACCTGATGTGTCTTC 860 870 880 890 900 910 --------------------------------------------------------------------------- >>HUMCAPLL L07772 Human cathepsin-L like (CTSLL) gene, exons 1 through 7, com (7211 nt) initn: 3622 init1: 949 opt: 1481 Z-score: 1224.5 expect() 3.3e-62 87.887% identity in 388 nt overlap Entrez lookup Re-search database >HUMCAP 1188-1575: ----------------: 1150 1160 1170 1180 1190 1200 1210 1220 QUERY GCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAG :::::::::: :: : :::::::::: ::::::: ::::: HUMCAP GCTTTATCCTTCCTCTGAAATGGAAAACCTGCTCTCCTTTCAGCTGGGGTAAAAACTGGGGCATGGATGGCTACATAAAG 5020 5030 5040 5050 5060 5070 5080 5090 1230 1240 1250 1260 1270 1280 1290 1300 QUERY ATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGACGGTGATG ::::::::::::::::: ::: : :::::::::::: :::::::::::::::::::::::::::::: :::: ::::::: HUMCAP ATGGCCAAAGACCGGAGGAACAACTGTGGAATTGCCACAGCAGCCAGCTACCCCACTGTGTGAGCTGATGGATGGTGATG 5100 5110 5120 5130 5140 5150 5160 5170 1310 1320 1330 1340 1350 1360 1370 1380 QUERY AGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCAGTCTACCAGCCCCCGCTGTGTCGGATACAC :::::: ::::::::: ::::::: ::: :: ::::::::: ::::::: ::::::::: :: ::::::: : :: ::: HUMCAP AGGAAGAACTTGACTGAGGATGGCACATCCAAAGGAGGAATTTATCTTCAATCTACCAGCACCTGCTGTGTTGAATGCAC 5180 5190 5200 5210 5220 5230 5240 5250 1390 1400 1410 1420 1430 1440 1450 1460 QUERY ACTCGAATCATTGAAGATCCGAGTGTGATTTGAATTCTGTGATATTTTCACACTGGTAAATGTTACCTCTATTTTAATTA ::: ::::::::::::::: ::::::: : :::::: ::::::::::::::::::::::::::::: ::::::::::: HUMCAP ACTTCAATCATTGAAGATCCAAGTGTGAGTGGAATTC--TGATATTTTCACACTGGTAAATGTTACCTGTATTTTAATTA 5260 5270 5280 5290 5300 5310 5320 5330 1470 1480 1490 1500 1510 1520 1530 1540 QUERY CTGCTATAAATAGGTTTATATTATTGATTCACTTACTGACTTTGCATTTTCGTTTTTAAAAGGATGTATAAATTTTTACC :::::::::: : :::: :::::::::::::::: :::::: :::::: :::::::::::: :::: : ::::::: HUMCAP CTGCTATAAACATGTTTGTATTATTGATTCACTT----ACTTTGTATTTTC-ATTTTAAAAGGATATATACAATTTTACC 5340 5350 5360 5370 5380 5390 5400 5410 1550 1560 1570 QUERY TGTTTAAATAAAATTTAATTTCAAATGT :::::::::::: : ::::::::::::: HUMCAP TGTTTAAATAAACTGTAATTTCAAATGTACTGGTGGGGCTTCTTTCTGTTTTGAAGCACTGACTTTGTGTAGTTGTATTA 5420 5430 5440 5450 5460 5470 5480 5490 --------------------------------------------------------------------------- >>HUMCATHLA L06426 Human cathepsin L (CTSL) gene, exon 1, intron 1, and exon (1484 nt) initn: 1400 init1: 1400 opt: 1400 Z-score: 1167.0 expect() 2.5e-58 100.000% identity in 280 nt overlap Entrez lookup Re-search database >HUMCAT 1- 280:------------ : 10 20 30 40 50 60 70 80 QUERY AGAACCGCGACCTCCGCAACCTTGAGCGGCATCCGTGGAGTGCGCCTGCAGCTACGACCGCAGCAGGAAAGCGCCGCCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMCAT AGAACCGCGACCTCCGCAACCTTGAGCGGCATCCGTGGAGTGCGCCTGCAGCTACGACCGCAGCAGGAAAGCGCCGCCGG 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 QUERY CCAGGCCCAGCTGTGGCCGGACAGGGACTGGAAGAGAGGACGCGGTCGAGTAGGTGTGCACCAGCCCTGGCAACGAGAGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMCAT CCAGGCCCAGCTGTGGCCGGACAGGGACTGGAAGAGAGGACGCGGTCGAGTAGGTGTGCACCAGCCCTGGCAACGAGAGC 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 QUERY GTCTACCCCGAACTCTGCTGGCCTTGAGGTGGGGAAGCCGGGGAGGGCAGTTGAGGACCCCGCGGAGGCGCGTGACTGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HUMCAT GTCTACCCCGAACTCTGCTGGCCTTGAGGTGGGGAAGCCGGGGAGGGCAGTTGAGGACCCCGCGGAGGCGCGTGACTGGT 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 QUERY TGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGTTTTAAAACATGAATCCTACACTCATCCTTGCTGCCTTTTG :::::::::::::::::::::::::::::::::::::::: HUMCAT TGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGTACCGCAGCCAGGCCGGCGCCAACGACTCAGGGCCTGGCCC 250 260 270 280 290 300 310 320 --------------------------------------------------------------------------- >>CATPDP M31652 Cat progesterone-dependent protein mRNA, partial cds. 6/90 (421 nt) initn: 1332 init1: 1332 opt: 1343 Z-score: 1127.5 expect() 1.4e-55 80.144% identity in 418 nt overlap Entrez lookup Re-search database >CATPDP 825-1242: ------------------: 790 800 810 820 830 840 850 860 QUERY TGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGAT ::: :::::::: ::: ::::::::::::::::: :::: CATPDP GTGGCGGCCTAATTGATGATGCTTTCCAGTATGTTAAGGAC 10 20 30 40 870 880 890 900 910 920 930 940 QUERY AATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGT :: :::::::::::::: :::::::::::::::::: : ::: : ::: ::::: :: :::: :: :: : ::::: CATPDP AACGGAGGCCTGGACTCAGAGGAATCCTATCCATATCATGCACAGGGAGACTCCTGCAAATACAGGCCTGAGAACTCTGT 50 60 70 80 90 100 110 120 950 960 970 980 990 1000 1010 1020 QUERY TGCTAATGACACCGGCTTTGTGGACATCCCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTT ::: :::: ::: : :: ::::::::::: ::::::: : :: :::: :: : ::: ::::::::::::: : CATPDP TGCCAATGTCACTGACTACTGGGACATCCCTAGTAAGGAGAATGAACTTATGATCACATTGGCAGCTGTGGGGCCCATCT 130 140 150 160 170 180 190 200 1030 1040 1050 1060 1070 1080 1090 1100 QUERY CTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAA ::: :::::: :::::: : : :: :::::: :::::::::::::::::::::: ::: ::: ::::::::::::: CATPDP CTGCTGCTATAGATGCAAGCCTGGATACCTTCCGCTTCTATAAAGAAGGCATTTATTATGATCCAAGCTGTAGCAGTGAA 210 220 230 240 250 260 270 280 1110 1120 1130 1140 1150 1160 1170 1180 QUERY GACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAA ::: ::::::: ::::: :::::::::::::: :: ::: : ::::: :::: ::::: ::::: ::: : : :: CATPDP GACGTGGATCACGGTGTTCTGGTGGTTGGCTATGGTGCTGATGGAACAGAGACAGAGAACAAAAAATACTGGATTATCAA 290 300 310 320 330 340 350 360 1190 1200 1210 1220 1230 1240 1250 1260 QUERY GAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCT :::::::::::: ::: :::::::::: ::::::: :::::::::::::::::::: CATPDP AAACAGCTGGGGTACAGACTGGGGCATGGATGGCTACATAAAGATGGCCAAAGACCGGGA 370 380 390 400 410 420 1270 1280 1290 1300 1310 1320 1330 1340 QUERY CAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAG --------------------------------------------------------------------------- >>RABOC2 D14036 Rabbit mRNA for OC-2 protein, complete cds. 2/96 (1599 nt) initn: 775 init1: 206 opt: 1138 Z-score: 947.2 expect() 4.1e-46 61.029% identity in 875 nt overlap Entrez lookup Re-search database >RABOC2 351-1206: -------------------------------------- : 320 330 340 350 360 370 380 390 QUERY CTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCG ::: : : : :: : :::::: :::::: : RABOC2 AGGTTCTGCTGCTACCCGTGGTGAGTTTTGCTCTGCACCCTGAGGAAATACTGGACACCCAGTGGGAGCTATGGAAGAAG 40 50 60 70 80 90 100 110 400 410 420 430 440 450 460 QUERY ATGCACAACA--GATTAT-ACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGA : ::: :: : ::: :: ::: : :: ::: : :: : : : ::::: :: ::: ::::: ::: RABOC2 ACCTACAGCAAGCAGTATAACAGCAAGGTGGATGAAATCTCTCGGCGTTTAATTTGGGAAAAAAACCTGAAGCATATTTC 120 130 140 150 160 170 180 190 470 480 490 500 510 520 530 540 QUERY ACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAG : :: :: : ::: : :: :: : : : ::::::::::: : : :: :::::::::::::::: RABOC2 TATCCATAACCTTGAAGCCTCTCTTGGTGTCCATACATATGAACTGGCCATGAACCACCTGGGGGACATGACCAGTGAAG 200 210 220 230 240 250 260 270 550 560 570 580 590 600 610 QUERY AATTCAGGCAGGTGATGAATGGCTTTCAAA--AC--------CGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCT : : ::: ::::: :::: ::::: :: ::: : ::: :: : : : : : :: :: RABOC2 AGGTGGTTCAGAAGATGACTGGC-CTCAAAGTACCCCCGTCTCGTTCCCACAGTAATGACACACT-CTACATCCCTGACT 280 290 300 310 320 330 340 350 620 630 640 650 660 670 680 690 QUERY GTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGT : :: ::::::: :: : :: : :: :::: :: ::::: :::::::: :: :: ::::::::::::::: RABOC2 GGGAGGGCAGAACCCCAGACTCCATCGACTATCGAAAGAAGGGATACGTTACTCCTGTCAAAAACCAGGGTCAGTGTGGT 360 370 380 390 400 410 420 430 700 710 720 730 740 750 760 770 QUERY TCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGA :: ::::::::::: :: :: ::::: :: :: :: ::: : ::: ::::: : :: : ::::: RABOC2 TCCTGTTGGGCTTTCAGCTCTGTGGGTGCCCTCGAGGGCCAGCTCAAGAAGAAGACTGGCAAACTCTTAAACCTGAGCCC 440 450 460 470 480 490 500 510 780 790 800 810 820 830 840 850 QUERY GCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATG ::::: ::::: :: :: :: : :: : ::: : ::::: :: ::: ::: :::: :::::::::: RABOC2 CCAGAACCTGGTGGATTG---TGTGTCT---GAGAATTATGGCTGTGGAGGGGGCTACATGACCAATGCCTTCCAGTATG 520 530 540 550 560 570 580 860 870 880 890 900 910 920 930 QUERY TTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAG : ::: :: : ::: : :::::::: :: :::: :: :: : :: : :: ::: :::: ::::::::: : RABOC2 TGCAGAGGAACCGGGGCATTGACTCTGAAGATGCCTACCCCTACGTGGGACAGGATGAAAGTTGTATGTACAATCCGACT 590 600 610 620 630 640 650 660 940 950 960 970 980 990 1000 1010 QUERY TATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTAA---GCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGT : :: :: :: :: : :: :::::: : : : ::::: ::::::: :: :::::: :: :: RABOC2 GGCAAGGCAGCCAAATGCAGAGGGTACAGAGAGATCCCTGAGGGGAATGAGAAAGCCCTGAAGAGGGCAGTGGCCCGAGT 670 680 690 700 710 720 730 740 1020 1030 1040 1050 1060 1070 1080 1090 QUERY GGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACT ::: ::: : ::::: :: ::::::::: : : ::::::: ::: :: : :::: : :::: ::: : ::: RABOC2 GGGACCCGTCTCTGTGGCCATTGATGCAAGCCTGACCTCCTTCCAGTTTTACAGTAAAGGTGTATATTATGATGAAAACT 750 760 770 780 790 800 810 820 1100 1110 1120 1130 1140 1150 1160 1170 QUERY GTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATT--TGAAAGCACAGAATCAGATAACAATAAAT : :: ::::: : :: : :::: :: ::: :: ::::: ::: : ::: : : : :: :: : ::: :: RABOC2 GCAGTAGTGACAATGTGAACCATGCGGTTTTGGCCGTGGGCTATGGAATCCAGAAGGGAAATAAGCACTGGATAATTAAG 830 840 850 860 870 880 890 900 1180 1190 1200 1210 1220 1230 1240 1250 QUERY ATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCAT : ::::: : :::: :::::::: :: :: :: RABOC2 AACAGCTGG-GGAGAA-AGCTGGGG-AAACAAAGGCTATATCCTCATGGCTCGGAATAAGAACAACGCCTGTGGCATTGC 910 920 930 940 950 960 970 980 --------------------------------------------------------------------------- >>S39127 cathepsin S=cysteine proteinase [human, testis, mRNA, 1784 nt]. 9/9 (1784 nt) initn: 800 init1: 319 opt: 1076 Z-score: 894.5 expect() 3.2e-43 60.748% identity in 856 nt overlap Entrez lookup Re-search database >S39127 383-1220: ------------------------------------- : 350 360 370 380 390 400 410 420 QUERY CTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATGAAGA : :: : ::: :::: :: : : : ::::::::: S39127 ATAAAGATCCTACCCTGGATCACCACTGGCATCTCTGGAAGAAAACCTATGGCAAACA-ATACAAGGAAAAGAATGAAGA 220 230 240 250 260 270 280 290 430 440 450 460 470 480 490 QUERY AGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGA--ATACA--GGGAAGGGAAA :: : : : : ::::: ::::: : ::: : : :: ::::: : ::: :: :: ::::: : : S39127 AGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAGCATTCAATGGGAATGCACT 300 310 320 330 340 350 360 370 500 510 520 530 540 550 560 570 QUERY CACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAA :: : :: ::: ::::::: : : ::::::::::::::::::::: : : : :::::: : : : : S39127 CATACGATC----TGGGCATGAACCACCTGGGAGACATGACCAGTGAAGAAGTGATGTCTTTGATGAGTTCCCTGAGAGT 380 390 400 410 420 430 440 580 590 600 610 620 630 640 650 QUERY CCGTAAGCCCAGGAAGGGGAAAGT--GTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGA : : : :: :: : :: : : : : : : : :: :: :: :::::::: :::::::::: S39127 TCCCAGCCAGTGGCAGAGAAATATCACATATAAGTCAAACCCTAATCGGATATTGCCTGATTCTGTGGACTGGAGAGAGA 450 460 470 480 490 500 510 520 660 670 680 690 700 710 720 730 QUERY AAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGA :::: : :: ::: ::::: :::: ::: :::::: :::: :::::::: :::::: :: :: :: :::: : S39127 AAGGGTGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCA 530 540 550 560 570 580 590 600 740 750 760 770 780 790 800 810 QUERY CAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCT---CTGGGCCTCAAGGCAA ::: :: : :::::: :: : ::: : :: :: :::: ::::: ::::: :: :::: ::: : :: :: S39127 CAGCTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAA 610 620 630 640 650 660 670 680 820 830 840 850 860 870 880 890 QUERY TGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCT ::::::::::::::::: : ::: ::::::::::: : ::::: ::: : ::::: :: : :::: S39127 CAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCT 690 700 710 720 730 740 750 760 900 910 920 930 940 950 960 970 QUERY ATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTA-ATGACACCGGCTTTGTGGACAT :::: :: : :: : :: : ::: : :: : : :: ::: :: ::: : ::: : :: :: : S39127 ATCCCTACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTT 770 780 790 800 810 820 830 840 980 990 1000 1010 1020 1030 1040 QUERY CCCTAAGCAGGAGAAG--GCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGA :: :: : :::::: : ::::: : :: :: :: : : :: :: : ::::::: : : ::::: ::::: S39127 CCTTATGGCAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCC 850 860 870 880 890 900 910 920 1050 1060 1070 1080 1090 1100 1110 1120 QUERY GTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGG :: ::: : :::: : : :: : :: : ::: ::: :::: : : : : :: :::::::::: :: :::: S39127 TTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGT---ACTCAGAATGTGAATCATGGTGTACTTGTGG 930 940 950 960 970 980 990 1000 1130 1140 1150 1160 1170 1180 1190 1200 QUERY TTGGCTACG--GAT-TTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGG ::::::: : ::: :: : : : ::::: : : :: : ::::: : ::: :: ::::::::: : S39127 TTGGCTATGGTGATCTTAATGGGAAAGAAT-ACTGGCTTGTGAAAAACAGCTGGGG--CCACAACTTTGGTGAAGAAGGA 1010 1020 1030 1040 1050 1060 1070 1080 1210 1220 1230 1240 1250 1260 1270 1280 QUERY GGCAT--GGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACT :: :: :::: : S39127 TATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTTCCCTCTTACCCAGAAATCTAGAGGATCTC 1090 1100 1110 1120 1130 1140 1150 1160 --------------------------------------------------------------------------- >>HUMCATS M90696 Human cathepsin S (CTSS) mRNA, complete cds. 7/96 (1763 nt) initn: 800 init1: 319 opt: 1067 Z-score: 887.1 expect() 8.3e-43 60.631% identity in 856 nt overlap Entrez lookup Re-search database >HUMCAT 383-1220: ------------------------------------- : 350 360 370 380 390 400 410 420 QUERY CTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATGAAGA : :: : ::: :::: :: : : : ::::::::: HUMCAT ATAAAGATCCTACCCTGGATCACCACTGGCATCTCTGGAAGAAAACCTATGGCAAACA-ATACAAGGAAAAGAATGAAGA 200 210 220 230 240 250 260 270 430 440 450 460 470 480 490 QUERY AGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGA--ATACA--GGGAAGGGAAA :: : : : : ::::: ::::: : ::: : : :: ::::: : ::: :: :: ::::: : : HUMCAT AGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAGCATTCAATGGGAATGCACT 280 290 300 310 320 330 340 350 500 510 520 530 540 550 560 570 QUERY CACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAA :: : :: ::: ::::::: : : ::::::::::::::::::::: : : : :::::: : : : : HUMCAT CATACGATC----TGGGCATGAACCACCTGGGAGACATGACCAGTGAAGAAGTGATGTCTTTGATGAGTTCCCTGAGAGT 360 370 380 390 400 410 420 580 590 600 610 620 630 640 650 QUERY CCGTAAGCCCAGGAAGGGGAAAGT--GTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGA : : : :: :: : :: : : : : : : : :: :: :: :::::::: :::::::::: HUMCAT TCCCAGCCAGTGGCAGAGAAATATCACATATAAGTCAAACCCTAATCGGATATTGCCTGATTCTGTGGACTGGAGAGAGA 430 440 450 460 470 480 490 500 660 670 680 690 700 710 720 730 QUERY AAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGA :::: : :: ::: ::::: :::: ::: :::::: :::: :::::::: :::::: :: :: :: :::: : HUMCAT AAGGGTGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCA 510 520 530 540 550 560 570 580 740 750 760 770 780 790 800 810 QUERY CAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCT---CTGGGCCTCAAGGCAA ::: :: : :::::: :: : ::: : :: :: :::: ::::: ::::: :: :::: ::: : :: :: HUMCAT CAGCTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAA 590 600 610 620 630 640 650 660 820 830 840 850 860 870 880 890 QUERY TGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCT ::::::::::::::::: : ::: ::::::::::: : ::::: ::: : ::::: :: : :::: HUMCAT CAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCT 670 680 690 700 710 720 730 740 900 910 920 930 940 950 960 970 QUERY ATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTA-ATGACACCGGCTTTGTGGACAT :::: :: : :: : :: ::: : :: : : :: ::: :: ::: : ::: : :: :: : HUMCAT ATCCCTACAAAGCCATGGATCTGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTT 750 760 770 780 790 800 810 820 980 990 1000 1010 1020 1030 1040 QUERY CCCTAAGCAGGAGAAG--GCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGA :: :: : :::::: : ::::: : :: :: :: : : :: :: : ::::::: : : ::::: ::::: HUMCAT CCTTATGGCAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCC 830 840 850 860 870 880 890 900 1050 1060 1070 1080 1090 1100 1110 1120 QUERY GTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGG :: ::: : :::: : : :: : :: : ::: ::: :::: : : : : :: :::::::::: :: :::: HUMCAT TTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGT---ACTCAGAATGTGAATCATGGTGTACTTGTGG 910 920 930 940 950 960 970 980 1130 1140 1150 1160 1170 1180 1190 1200 QUERY TTGGCTACG--GAT-TTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGG ::::::: : ::: :: : : : ::::: : : :: : ::::: : ::: :: ::::::::: : HUMCAT TTGGCTATGGTGATCTTAATGGGAAAGAAT-ACTGGCTTGTGAAAAACAGCTGGGG--CCACAACTTTGGTGAAGAAGGA 990 1000 1010 1020 1030 1040 1050 1060 1210 1220 1230 1240 1250 1260 1270 1280 QUERY GGCAT--GGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACT :: :: :::: : HUMCAT TATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTTCCCTCTTACCCAGAAATCTAGAGGATCTC 1070 1080 1090 1100 1110 1120 1130 1140 --------------------------------------------------------------------------- >>HUMCATSS M86553 Human cathepsin S mRNA, complete cds. 2/92 (1255 nt) initn: 783 init1: 319 opt: 1058 Z-score: 881.8 expect() 2.3e-42 60.514% identity in 856 nt overlap Entrez lookup Re-search database >HUMCAT 383-1220: ------------------------------------- : 350 360 370 380 390 400 410 420 QUERY CTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATGAAGA : :: : ::: :::: :: : : : ::::::::: HUMCAT ATAAAGATCCTACCCTGGATCACCACTGGCATCTCTGGAAGAAAACCTATGGCAAACA-ATACAAGGAAAAGAATGAAGA 70 80 90 100 110 120 130 140 430 440 450 460 470 480 490 QUERY AGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGA--ATACA--GGGAAGGGAAA :: : : : : ::::: ::::: : ::: : : :: ::::: : ::: :: :: ::::: : : HUMCAT AGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAGCATTCAATGGGAATGCACT 150 160 170 180 190 200 210 220 500 510 520 530 540 550 560 570 QUERY CACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAA :: : :: ::: ::::::: : : ::::::::::::::::::::: : : : ::: :: : : : : HUMCAT CATACGATC----TGGGCATGAACCACCTGGGAGACATGACCAGTGAAGAAGTGATGTCTTTGACGAGTTCCCTGAGAGT 230 240 250 260 270 280 290 580 590 600 610 620 630 640 650 QUERY CCGTAAGCCCAGGAAGGGGAAAGT--GTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGA : : : :: :: : :: : : : : : : : :: :: :: :::::::: :::::::::: HUMCAT TCCCAGCCAGTGGCAGAGAAATATCACATATAAGTCAAACCCTAATCGGATATTGCCTGATTCTGTGGACTGGAGAGAGA 300 310 320 330 340 350 360 370 660 670 680 690 700 710 720 730 QUERY AAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGA :::: : :: ::: ::::: :::: ::: :::::: :::: :::::::: :::::: :: :: :: :::: : HUMCAT AAGGGTGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCA 380 390 400 410 420 430 440 450 740 750 760 770 780 790 800 810 QUERY CAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCT---CTGGGCCTCAAGGCAA ::: :: : :::::: :: : ::: : : :: :::: ::::: ::::: :: :::: ::: : :: :: HUMCAT CAGCTGAAGCTGAAAACAGGAAAGCTGGTGACTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAA 460 470 480 490 500 510 520 530 820 830 840 850 860 870 880 890 QUERY TGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCT ::::::::::::::::: : ::: ::::::::::: : ::::: ::: : ::::: :: : :::: HUMCAT CAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCT 540 550 560 570 580 590 600 610 900 910 920 930 940 950 960 970 QUERY ATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTA-ATGACACCGGCTTTGTGGACAT :::: :: : :: : :: : ::: : :: : : :: ::: :: ::: : ::: : :: :: : HUMCAT ATCCCTACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTT 620 630 640 650 660 670 680 690 980 990 1000 1010 1020 1030 1040 QUERY CCCTAAGCAGGAGAAG--GCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGA :: :: : :::::: : ::::: : :: :: :: : : :: :: : ::::::: : : ::::: ::::: HUMCAT CCTTATGGGAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCC 700 710 720 730 740 750 760 770 1050 1060 1070 1080 1090 1100 1110 1120 QUERY GTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGG :: ::: : :::: : : :: : :: : ::: ::: :::: : : : : :: :::::::::: :: :::: HUMCAT TTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGT---ACTCAGAATGTGAATCATGGTGTACTTGTGG 780 790 800 810 820 830 840 850 1130 1140 1150 1160 1170 1180 1190 1200 QUERY TTGGCTACG--GAT-TTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGG ::::::: : ::: :: : : : ::::: : : :: : ::::: : ::: :: ::::::::: : HUMCAT TTGGCTATGGTGATCTTAATGGGAAAGAAT-ACTGGCTTGTGAAAAACAGCTGGGG--CCACAACTTTGGTGAAGAAGGA 860 870 880 890 900 910 920 930 1210 1220 1230 1240 1250 1260 1270 1280 QUERY GGCAT--GGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACT :: :: :::: : HUMCAT TATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTTCCCTCTTACCCAGAAATCTAGAGGATCTC 940 950 960 970 980 990 1000 1010 --------------------------------------------------------------------------- >>S93414 cathepsin S=elastinolytic cysteine protease [human, alveolar macrop (1255 nt) initn: 783 init1: 319 opt: 1058 Z-score: 881.8 expect() 2.3e-42 60.514% identity in 856 nt overlap Entrez lookup Re-search database >S93414 383-1220: ------------------------------------- : 350 360 370 380 390 400 410 420 QUERY CTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATGAAGA : :: : ::: :::: :: : : : ::::::::: S93414 ATAAAGATCCTACCCTGGATCACCACTGGCATCTCTGGAAGAAAACCTATGGCAAACA-ATACAAGGAAAAGAATGAAGA 70 80 90 100 110 120 130 140 430 440 450 460 470 480 490 QUERY AGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGA--ATACA--GGGAAGGGAAA :: : : : : ::::: ::::: : ::: : : :: ::::: : ::: :: :: ::::: : : S93414 AGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAGCATTCAATGGGAATGCACT 150 160 170 180 190 200 210 220 500 510 520 530 540 550 560 570 QUERY CACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAA :: : :: ::: ::::::: : : ::::::::::::::::::::: : : : ::: :: : : : : S93414 CATACGATC----TGGGCATGAACCACCTGGGAGACATGACCAGTGAAGAAGTGATGTCTTTGACGAGTTCCCTGAGAGT 230 240 250 260 270 280 290 580 590 600 610 620 630 640 650 QUERY CCGTAAGCCCAGGAAGGGGAAAGT--GTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGA : : : :: :: : :: : : : : : : : :: :: :: :::::::: :::::::::: S93414 TCCCAGCCAGTGGCAGAGAAATATCACATATAAGTCAAACCCTAATCGGATATTGCCTGATTCTGTGGACTGGAGAGAGA 300 310 320 330 340 350 360 370 660 670 680 690 700 710 720 730 QUERY AAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGA :::: : :: ::: ::::: :::: ::: :::::: :::: :::::::: :::::: :: :: :: :::: : S93414 AAGGGTGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCA 380 390 400 410 420 430 440 450 740 750 760 770 780 790 800 810 QUERY CAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCT---CTGGGCCTCAAGGCAA ::: :: : :::::: :: : ::: : : :: :::: ::::: ::::: :: :::: ::: : :: :: S93414 CAGCTGAAGCTGAAAACAGGAAAGCTGGTGACTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAA 460 470 480 490 500 510 520 530 820 830 840 850 860 870 880 890 QUERY TGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCT ::::::::::::::::: : ::: ::::::::::: : ::::: ::: : ::::: :: : :::: S93414 CAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCT 540 550 560 570 580 590 600 610 900 910 920 930 940 950 960 970 QUERY ATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTA-ATGACACCGGCTTTGTGGACAT :::: :: : :: : :: : ::: : :: : : :: ::: :: ::: : ::: : :: :: : S93414 ATCCCTACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTT 620 630 640 650 660 670 680 690 980 990 1000 1010 1020 1030 1040 QUERY CCCTAAGCAGGAGAAG--GCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGA :: :: : :::::: : ::::: : :: :: :: : : :: :: : ::::::: : : ::::: ::::: S93414 CCTTATGGGAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCC 700 710 720 730 740 750 760 770 1050 1060 1070 1080 1090 1100 1110 1120 QUERY GTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGG :: ::: : :::: : : :: : :: : ::: ::: :::: : : : : :: :::::::::: :: :::: S93414 TTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGT---ACTCAGAATGTGAATCATGGTGTACTTGTGG 780 790 800 810 820 830 840 850 1130 1140 1150 1160 1170 1180 1190 1200 QUERY TTGGCTACG--GAT-TTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGG ::::::: : ::: :: : : : ::::: : : :: : ::::: : ::: :: ::::::::: : S93414 TTGGCTATGGTGATCTTAATGGGAAAGAAT-ACTGGCTTGTGAAAAACAGCTGGGG--CCACAACTTTGGTGAAGAAGGA 860 870 880 890 900 910 920 930 1210 1220 1230 1240 1250 1260 1270 1280 QUERY GGCAT--GGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACT :: :: :::: : S93414 TATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTTCCCTCTTACCCAGAAATCTAGAGGATCTC 940 950 960 970 980 990 1000 1010 --------------------------------------------------------------------------- >>AF038546 Mus musculus cathepsin S precursor, mRNA, complete cds. 1/98 (1305 nt) initn: 990 init1: 467 opt: 989 Z-score: 823.7 expect() 3.8e-39 59.505% identity in 889 nt overlap Entrez lookup Re-search database >AF0385 398-1262: -------------------------------------- : 360 370 380 390 400 410 420 430 QUERY AGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGATTATACGG-CATGAATGAAGAAGGATGGAGGAGAG : ::: :: : :: : ::::::::::: : :: : AF0385 CCTGGACTACCATTGGGATCTCTGGAAGAAAACCCATGAGAAAGAATACAAGGATAAGAATGAAGAAGAAGTACGGCGTC 150 160 170 180 190 200 210 220 440 450 460 470 480 490 500 510 QUERY CAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCC : ::::: ::::: ::::: : :: : ::::::: ::::: :: : :: : :: : : ::: : AF0385 TCATCTGGGAAAAGAATCTGAAGTTTATAATGATTCACAATCTCGAATATTCTATGGGAATGCATACCTACCAAGTGGGC 230 240 250 260 270 280 290 300 520 530 540 550 560 570 580 590 QUERY ATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAA----CCGTAAGCCCAGGA ::::::: : ::::::::::::: ::::::: :: : :::: : ::: : : :: ::: :: : :: AF0385 ATGAACGATATGGGAGACATGACCAATGAAGAAATCTCGTGTCGGATGGGT-GCTCTGAGAATTTCCCGACAGTCTCCGA 310 320 330 340 350 360 370 380 600 610 620 630 640 650 660 QUERY AGGGGAAAGT--GTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGAAAGGCTACGTGACT : :: :: :: :::: :: : : :: :: :: ::::::: ::::::::::: :::: ::: ::: AF0385 A---GACTGTCACTTTCAGGTCATACTCTAATCGGACATTGCCTGACACTGTGGACTGGAGAGAGAAGGGCTGCGTCACT 390 400 410 420 430 440 450 460 670 680 690 700 710 720 730 740 QUERY CCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAA ::::: : :::::: :::::: : ::::::::::: :::::: :: :: :::::::: ::: :: : ::: AF0385 GAGGTGAAATACCAGGGTTCTTGTGGTGCCTGTTGGGCTTTCAGTGCTGTGGGGGCCCTTGAAGGGCAGCTGAAGCTGAA 470 480 490 500 510 520 530 540 750 760 770 780 790 800 810 820 QUERY AACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTC------TGGGCCTCAAGGCAATGAAGGCTGCA ::: :::: ::: :: :: :: :::: ::::: ::::: :::::::: : : :: ::: ::::::: AF0385 AACGGGGAAGCTGATATCCCTCAGTGCTCAGAACCTGGTGGACTGCTCAAATGAAGAAAAGTATGGGAATAAAGGCTGTG 550 560 570 580 590 600 610 620 830 840 850 860 870 880 890 900 QUERY ATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAG :: ::: ::: : ::::::::::: : :::::::: ::: : :: : :: : :::::::: :: : AF0385 GAGGCGGCTACATGACCGAAGCTTTCCAGTACATCATTGATAATGGGGGCATAGAGGCAGACGCTTCCTATCCCTACAAA 630 640 650 660 670 680 690 700 910 920 930 940 950 960 970 980 QUERY GCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTA-ATGACACCGGCTTTGTGGACATCCCTAAGCAGG :: : :: ::: ::: : :: :: : :: :: : ::::: :: :: : : :::: : : AF0385 GCCATGGATGAAAAGTGTCACTATAACTCAAAAAATCGAGCTGCTACGTGTTCAAGGTACATTCAGCTCCCCTTTGGTGA 710 720 730 740 750 760 770 780 990 1000 1010 1020 1030 1040 1050 QUERY AGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCA---TTTCTGTTGCTATTG--ATGCAGGTCA-TGAGTCCTTC :::: : :::: : :: : :::: : : :::: :: : : :: : : :: : :::: : AF0385 CGAAGATGC-CCTGAAAGAAG------CAGTGGCCACTAAAGGGCCTGTCTCTGTGGGCATCGACGCCAGCCATTCCTCC 790 800 810 820 830 840 850 1060 1070 1080 1090 1100 1110 1120 1130 QUERY CTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTA : :::: : :: :: : : ::: :: : : : : :: :::::::::: :: ::::::::::: AF0385 TTCTTCTTCTACAAAAGCGGTGTCTATGACGACCCCTCCTGTACGGGCAATGTGAATCATGGTGTTCTTGTGGTTGGCTA 860 870 880 890 900 910 920 930 1140 1150 1160 1170 1180 1190 1200 1210 QUERY CGGATTTGAAAGCACAGAATC-AGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGG--TGAAGAATGGGGCATGG :: :: :: ::: ::: : :: ::::: ::::: ::::: ::::: : :: ::: : :: AF0385 TGG-------------GACTCTTGATGGCAAAGATTACTGGCTTGTGAAAAACAGTTGGGGCCTTAACTTTGGTG-AT-C 940 950 960 970 980 990 1000 1220 1230 1240 1250 1260 1270 1280 1290 QUERY GTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCT :: ::: : :::::: : : : : ::: :: :: :::::::: AF0385 AAGGATACATTCGGATGGCAAGAAATAATAAAAATCACTGCGGAATTGCTAGTTATTGCTCTTACCCAGAAATCTAAACC 1010 1020 1030 1040 1050 1060 1070 1080 1300 1310 1320 1330 1340 1350 1360 1370 QUERY GGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCAGTCTACCAGCCCCCGC AF0385 ATTTCTTCTTTTTCTAACAAGTCACAAAGATGGAATATACTCTAACTTAATTTGCCTGCAATATCCAGAGGAACCAAGTG 1090 1100 1110 1120 1130 1140 1150 1160 --------------------------------------------------------------------------- >>RATCTHS L03201 Rattus norvegicus cathepsin S mRNA, complete cds. 12/92 (1330 nt) initn: 661 init1: 301 opt: 986 Z-score: 821.1 expect() 5.2e-39 59.071% identity in 904 nt overlap Entrez lookup Re-search database >RATCTH 379-1262: --------------------------------------- : 340 350 360 370 380 390 400 410 QUERY TACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATG :: : : : : :: : : :::::: : ::::: RATCTH AGAGACCTACCCTGGACCACCACTGGGATCTCTGGAAGAAAACTCGCATGAGAAGGAATACAGATCA--------GAATG 80 90 100 110 120 130 140 150 420 430 440 450 460 470 480 490 QUERY AAGAAGGATGGAGGA-GAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGAATACAGGGAAGGGAA ::::: :: : : :: : : ::::: ::::: : ::: : :: :: ::::::: :::: : :: : RATCTH AAGAA-GACGTACGACGTCTCATCTGGGAAAAGAATCTCAAGTTTATAATGCTTCACAATCTGGAACATTCTATGGGAAT 160 170 180 190 200 210 220 230 500 510 520 530 540 550 560 570 QUERY ACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTC--- :: : :: ::: ::::::: : : ::::::::::: ::::::: ::: :::: :: : :::: :: RATCTH GCATTCATACAGTGTGGGCATGAACCACATGGGAGACATGACACCTGAAGAAGTCA--TAGGTTAT-ATGGGCTCTCTGA 240 250 260 270 280 290 300 580 590 600 610 620 630 640 QUERY AAAACCGTAAGCCCAGGAAGGGGAAAGTG-----TTCCAG-GAACCTCTGTTTTATGAGGCCCCCAGATCTGTGGATTGG :: : : :::: :::: : ::::: :: :: :: :::: : : ::: : :::::::: ::: RATCTH GAATTCCCAGGCCCTGGAATAG--AAGTGGCACTCTCAAGTCAAGCTCTAATCAGACATTGCCCGA-CTCTGTGGACTGG 310 320 330 340 350 360 370 380 650 660 670 680 690 700 710 720 QUERY AGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCT :::: :: :::: ::: ::: :::::: : ::::: :::::::: :: :::::::: :: :: :: :: :: RATCTH CGAGAAAAGGGCTGCGTCACTAATGTGAAATACCAGGGCTCTTGTGGTTCCTGCTGGGCTTTCAGCGCCGAGGGGGCCCT 390 400 410 420 430 440 450 460 730 740 750 760 770 780 790 800 QUERY TGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTC------TGGGC :::::: ::: :: : :::::: :::: ::: : :: :: :::: ::::: ::::: :: ::::: : RATCTH TGAAGGGCAGCTGAAGCTGAAAACGGGGAAGCTGGTGTCTCTCAGTGCTCAGAACCTGGTGGATTGCTCAACCGAAGAAA 470 480 490 500 510 520 530 540 810 820 830 840 850 860 870 880 QUERY CTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCT : :: ::: :::::::: :::::: : ::: : ::::::::::: : :::: :: :: : ::::: RATCTH AGTACGGGAATAAAGGCTGCGGGGGTGGCTTCATGACCGAAGCTTTCCAGTACATCATCGATA--CGA-GCATCGACTCA 550 560 570 580 590 600 610 620 890 900 910 920 930 940 950 960 QUERY GAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTT :: : :::::::: :: : :: : :: ::: ::: :: : :: :: :: : ::: : : : : RATCTH GAAGCTTCCTATCCCTACAAAGCCATGGATGAAAAGTGTCTCTATGACCCAAAAAATCGAGCTGCCACGTGTTCAAGGTA 630 640 650 660 670 680 690 700 970 980 990 1000 1010 1020 1030 QUERY TGTGGACATCCC--TAAGC-AGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATG : :: :::: : :: : :: : :: :::: : ::::: :: ::: ::::: : ::::: : :: :: : RATCTH CATTGAGCTCCCCTTCGGCGATGAAGAAGCTCTGAAAGAAGCAGTGGCCACTAAAGGGCCTGTCTCTGTGGGCATCGACG 710 720 730 740 750 760 770 780 1040 1050 1060 1070 1080 1090 1100 1110 QUERY CAGGTCATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGT : : :::: : : ::: : :: : : : ::: :: : : :: : ::: :::::::: RATCTH ACGCCAGCCATTCCTCCTTCTTCCTCTACCAAAGTGGTGTCTATGATGACCCCTCCTGTACCGAGAATATGAATCATGGT 790 800 810 820 830 840 850 860 1120 1130 1140 1150 1160 1170 1180 1190 QUERY GTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATC-AGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTG :: :: ::::::::::: :: :: :: ::: :: : :: ::::: ::::: ::::: ::::: RATCTH GTTCTCGTGGTTGGCTATGG-------------GACTCTTGATGGGAAAGACTACTGGCTTGTGAAAAACAGTTGGGGCC 870 880 890 900 910 920 1200 1210 1220 1230 1240 1250 1260 1270 QUERY AAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTAC : : :: :: :: : :::::: : : : : ::: :: :: :: ::::: RATCTH TTCACTTTGGTGATCAAGGATATATTCGGATGGCGAGAAATAACAAAAATCACTGCGGGATTGCTAGCTATTGCTCTTAC 930 940 950 960 970 980 990 1000 1280 1290 1300 1310 1320 1330 1340 1350 QUERY CCCACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCAG RATCTH CCAGAAATCTAAACCGTTTCTTCTTTTTCTAATGGGTCACAAAGACGGAATACACTCTAATTTAATTTTGTCTGCTCCAT 1010 1020 1030 1040 1050 1060 1070 1080 --------------------------------------------------------------------------- >>HSOC2RNA X82153 H.sapiens mRNA for cathepsin O. 4/95 (1669 nt) initn: 806 init1: 322 opt: 958 Z-score: 796.2 expect() 1e-37 64.395% identity in 587 nt overlap Entrez lookup Re-search database >HSOC2R 626-1206: -------------------------- : 590 600 610 620 630 640 650 660 QUERY CCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGAAAGGCTACG :: ::::::: ::::: :: : :: ::::::: :: : HSOC2R CCGCAGTAATGACACCCTTTATATCCCAGAATGGGAAGGTAGAGCCCCAGACTCTGTCGACTATCGAAAGAAAGGATATG 430 440 450 460 470 480 490 500 670 680 690 700 710 720 730 740 QUERY TGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTC : :::::::: :: :::::::::::::::::::: :::::::::::::: :: ::::: :: :: :: :: : HSOC2R TTACTCCTGTCAAAAATCAGGGTCAGTGTGGTTCCTGTTGGGCTTTTAGCTCTGTGGGTGCCCTGGAGGGCCAACTCAAG 510 520 530 540 550 560 570 580 750 760 770 780 790 800 810 820 QUERY CGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAA ::::::::: : :: : :::::: ::::: :: :: :: :: :: : :: : ::::: ::::: HSOC2R AAGAAAACTGGCAAACTCTTAAATCTGAGTCCCCAGAACCTAGTGGATTG---TGTGTCT---GAGAATGATGGCTGTGG 590 600 610 620 630 640 650 660 830 840 850 860 870 880 890 900 QUERY TGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGG :: ::: ::: :::: ::::: ::::: ::: : :: : :: : :::::::: :: :::: ::::::: :: HSOC2R AGGGGGCTACATGACCAATGCCTTCCAATATGTGCAGAAGAACCGGGGTATTGACTCTGAAGATGCCTACCCATATGTGG 670 680 690 700 710 720 730 740 910 920 930 940 950 960 970 980 QUERY CAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTAA---GCAG : ::::: :::: :::::: :: : : ::::: :: :: : :: ::::: : : : HSOC2R GACAGGAAGAGAGTTGTATGTACAACCCAACAGGCAAGGCAGCTAAATGCAGAGGGTACAGAGAGATCCCCGAGGGGAAT 750 760 770 780 790 800 810 820 990 1000 1010 1020 1030 1040 1050 1060 QUERY GAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTT ::::: ::::::: :: :::::: :: ::::: :: : ::::: :: ::::::::: : : ::::::: ::: HSOC2R GAGAAAGCCCTGAAGAGGGCAGTGGCCCGAGTGGGACCTGTCTCTGTGGCCATTGATGCAAGCCTGACCTCCTTCCAGTT 830 840 850 860 870 880 890 900 1070 1080 1090 1100 1110 1120 1130 1140 QUERY CTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGAT :: : :::: : :::: ::: : ::: : :: :: : :: : :::: :: ::: :: :: :: ::: HSOC2R TTACAGCAAAGGTGTGTATTATGATGAAAGCTGCAATAGCGATAATCTGAACCATGCGGTTTTGGCAGTGGGATATGGAA 910 920 930 940 950 960 970 980 1150 1160 1170 1180 1190 1200 1210 QUERY T--TGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCT : ::: : : : :: :: : ::: :: : ::::: : :::: : :::::: :: :: :: HSOC2R TCCAGAAGGGAAACAAGCACTGGATAATTAAAAACAGCTGG-GGAGAA-AACTGGGG-AAACAAAGGATATATCCTCATG 990 1000 1010 1020 1030 1040 1050 1220 1230 1240 1250 1260 1270 1280 1290 QUERY ACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGA HSOC2R GCTCGAAATAAGAACAACGCCTGTGGCATTGCCAACCTGGCCAGCTTCCCCAAGATGTGACTCCAGCCAGCCAAATCCAT 1060 1070 1080 1090 1100 1110 1120 1130 --------------------------------------------------------------------------- >>HSU13665 U13665 Human cathepsin O (CTSO) mRNA, complete cds. 4/95 (1661 nt) initn: 806 init1: 322 opt: 958 Z-score: 796.2 expect() 1e-37 64.395% identity in 587 nt overlap Entrez lookup Re-search database >HSU136 626-1206: -------------------------- : 590 600 610 620 630 640 650 660 QUERY CCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGAAAGGCTACG :: ::::::: ::::: :: : :: ::::::: :: : HSU136 CCGCAGTAATGACACCCTTTATATCCCAGAATGGGAAGGTAGAGCCCCAGACTCTGTCGACTATCGAAAGAAAGGATATG 410 420 430 440 450 460 470 480 670 680 690 700 710 720 730 740 QUERY TGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTC : :::::::: :: :::::::::::::::::::: :::::::::::::: :: ::::: :: :: :: :: : HSU136 TTACTCCTGTCAAAAATCAGGGTCAGTGTGGTTCCTGTTGGGCTTTTAGCTCTGTGGGTGCCCTGGAGGGCCAACTCAAG 490 500 510 520 530 540 550 560 750 760 770 780 790 800 810 820 QUERY CGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAA ::::::::: : :: : :::::: ::::: :: :: :: :: :: : :: : ::::: ::::: HSU136 AAGAAAACTGGCAAACTCTTAAATCTGAGTCCCCAGAACCTAGTGGATTG---TGTGTCT---GAGAATGATGGCTGTGG 570 580 590 600 610 620 630 830 840 850 860 870 880 890 900 QUERY TGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGG :: ::: ::: :::: ::::: ::::: ::: : :: : :: : :::::::: :: :::: ::::::: :: HSU136 AGGGGGCTACATGACCAATGCCTTCCAATATGTGCAGAAGAACCGGGGTATTGACTCTGAAGATGCCTACCCATATGTGG 640 650 660 670 680 690 700 710 910 920 930 940 950 960 970 980 QUERY CAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTAA---GCAG : ::::: :::: :::::: :: : : ::::: :: :: : :: ::::: : : : HSU136 GACAGGAAGAGAGTTGTATGTACAACCCAACAGGCAAGGCAGCTAAATGCAGAGGGTACAGAGAGATCCCCGAGGGGAAT 720 730 740 750 760 770 780 790 990 1000 1010 1020 1030 1040 1050 1060 QUERY GAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTT ::::: ::::::: :: :::::: :: ::::: :: : ::::: :: ::::::::: : : ::::::: ::: HSU136 GAGAAAGCCCTGAAGAGGGCAGTGGCCCGAGTGGGACCTGTCTCTGTGGCCATTGATGCAAGCCTGACCTCCTTCCAGTT 800 810 820 830 840 850 860 870 1070 1080 1090 1100 1110 1120 1130 1140 QUERY CTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGAT :: : :::: : :::: ::: : ::: : :: :: : :: : :::: :: ::: :: :: :: ::: HSU136 TTACAGCAAAGGTGTGTATTATGATGAAAGCTGCAATAGCGATAATCTGAACCATGCGGTTTTGGCAGTGGGATATGGAA 880 890 900 910 920 930 940 950 1150 1160 1170 1180 1190 1200 1210 QUERY T--TGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCT : ::: : : : :: :: : ::: :: : ::::: : :::: : :::::: :: :: :: HSU136 TCCAGAAGGGAAACAAGCACTGGATAATTAAAAACAGCTGG-GGAGAA-AACTGGGG-AAACAAAGGATATATCCTCATG 960 970 980 990 1000 1010 1020 1030 1220 1230 1240 1250 1260 1270 1280 1290 QUERY ACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGA HSU136 GCTCGAAATAAGAACAACGCCTGTGGCATTGCCAACCTGGCCAGCTTCCCCAAGATGTGACTCCAGCCAGCCAAATCCAT 1040 1050 1060 1070 1080 1090 1100 1110 --------------------------------------------------------------------------- >>HSU20280 U20280 Human cathepsin X mRNA, complete cds. 4/96 (1597 nt) initn: 806 init1: 322 opt: 958 Z-score: 796.5 expect() 1e-37 64.395% identity in 587 nt overlap Entrez lookup Re-search database >HSU202 626-1206: -------------------------- : 590 600 610 620 630 640 650 660 QUERY CCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGAAAGGCTACG :: ::::::: ::::: :: : :: ::::::: :: : HSU202 CCGCAGTAATGACACCCTTTATATCCCAGAATGGGAAGGTAGAGCCCCAGACTCTGTCGACTATCGAAAGAAAGGATATG 320 330 340 350 360 370 380 390 670 680 690 700 710 720 730 740 QUERY TGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTC : :::::::: :: :::::::::::::::::::: :::::::::::::: :: ::::: :: :: :: :: : HSU202 TTACTCCTGTCAAAAATCAGGGTCAGTGTGGTTCCTGTTGGGCTTTTAGCTCTGTGGGTGCCCTGGAGGGCCAACTCAAG 400 410 420 430 440 450 460 470 750 760 770 780 790 800 810 820 QUERY CGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAA ::::::::: : :: : :::::: ::::: :: :: :: :: :: : :: : ::::: ::::: HSU202 AAGAAAACTGGCAAACTCTTAAATCTGAGTCCCCAGAACCTAGTGGATTG---TGTGTCT---GAGAATGATGGCTGTGG 480 490 500 510 520 530 540 550 830 840 850 860 870 880 890 900 QUERY TGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGG :: ::: ::: :::: ::::: ::::: ::: : :: : :: : :::::::: :: :::: ::::::: :: HSU202 AGGGGGCTACATGACCAATGCCTTCCAATATGTGCAGAAGAACCGGGGTATTGACTCTGAAGATGCCTACCCATATGTGG 560 570 580 590 600 610 620 630 910 920 930 940 950 960 970 980 QUERY CAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTAA---GCAG : ::::: :::: :::::: :: : : ::::: :: :: : :: ::::: : : : HSU202 GACAGGAAGAGAGTTGTATGTACAACCCAACAGGCAAGGCAGCTAAATGCAGAGGGTACAGAGAGATCCCCGAGGGGAAT 640 650 660 670 680 690 700 710 990 1000 1010 1020 1030 1040 1050 1060 QUERY GAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTT ::::: ::::::: :: :::::: :: ::::: :: : ::::: :: ::::::::: : : ::::::: ::: HSU202 GAGAAAGCCCTGAAGAGGGCAGTGGCCCGAGTGGGACCTGTCTCTGTGGCCATTGATGCAAGCCTGACCTCCTTCCAGTT 720 730 740 750 760 770 780 790 1070 1080 1090 1100 1110 1120 1130 1140 QUERY CTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGAT :: : :::: : :::: ::: : ::: : :: :: : :: : :::: :: ::: :: :: :: ::: HSU202 TTACAGCAAAGGTGTGTATTATGATGAAAGCTGCAATAGCGATAATCTGAACCATGCGGTTTTGGCAGTGGGATATGGAA 800 810 820 830 840 850 860 870 1150 1160 1170 1180 1190 1200 1210 QUERY T--TGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCT : ::: : : : :: :: : ::: :: : ::::: : :::: : :::::: :: :: :: HSU202 TCCAGAAGGGAAACAAGCACTGGATAATTAAAAACAGCTGG-GGAGAA-AACTGGGG-AAACAAAGGATATATCCTCATG 880 890 900 910 920 930 940 1220 1230 1240 1250 1260 1270 1280 1290 QUERY ACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGA HSU202 GCTCGAAATAAGAACAACGCCTGTGGCATTGCCAACCTGGCCAGCTTCCCCAAGATGTGACTCCAGCCAGCCAAATCCAT 950 960 970 980 990 1000 1010 1020 --------------------------------------------------------------------------- >>S79895 OC2=cathepsin O2 [human, spleen, mRNA, 1482 nt]. 2/96 (1482 nt) initn: 806 init1: 322 opt: 958 Z-score: 797.0 expect() 1e-37 64.395% identity in 587 nt overlap Entrez lookup Re-search database >S79895 626-1206: -------------------------- : 590 600 610 620 630 640 650 660 QUERY CCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGAAAGGCTACG :: ::::::: ::::: :: : :: ::::::: :: : S79895 CCGCAGTAATGACACCCTTTATATCCCAGAATGGGAAGGTAGAGCCCCAGACTCTGTCGACTATCGAAAGAAAGGATATG 450 460 470 480 490 500 510 520 670 680 690 700 710 720 730 740 QUERY TGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTC : :::::::: :: :::::::::::::::::::: :::::::::::::: :: ::::: :: :: :: :: : S79895 TTACTCCTGTCAAAAATCAGGGTCAGTGTGGTTCCTGTTGGGCTTTTAGCTCTGTGGGTGCCCTGGAGGGCCAACTCAAG 530 540 550 560 570 580 590 600 750 760 770 780 790 800 810 820 QUERY CGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAA ::::::::: : :: : :::::: ::::: :: :: :: :: :: : :: : ::::: ::::: S79895 AAGAAAACTGGCAAACTCTTAAATCTGAGTCCCCAGAACCTAGTGGATTG---TGTGTCT---GAGAATGATGGCTGTGG 610 620 630 640 650 660 670 830 840 850 860 870 880 890 900 QUERY TGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGG :: ::: ::: :::: ::::: ::::: ::: : :: : :: : :::::::: :: :::: ::::::: :: S79895 AGGGGGCTACATGACCAATGCCTTCCAATATGTGCAGAAGAACCGGGGTATTGACTCTGAAGATGCCTACCCATATGTGG 680 690 700 710 720 730 740 750 910 920 930 940 950 960 970 980 QUERY CAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTAA---GCAG : ::::: :::: :::::: :: : : ::::: :: :: : :: ::::: : : : S79895 GACAGGAAGAGAGTTGTATGTACAACCCAACAGGCAAGGCAGCTAAATGCAGAGGGTACAGAGAGATCCCCGAGGGGAAT 760 770 780 790 800 810 820 830 990 1000 1010 1020 1030 1040 1050 1060 QUERY GAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTT ::::: ::::::: :: :::::: :: ::::: :: : ::::: :: ::::::::: : : ::::::: ::: S79895 GAGAAAGCCCTGAAGAGGGCAGTGGCCCGAGTGGGACCTGTCTCTGTGGCCATTGATGCAAGCCTGACCTCCTTCCAGTT 840 850 860 870 880 890 900 910 1070 1080 1090 1100 1110 1120 1130 1140 QUERY CTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGAT :: : :::: : :::: ::: : ::: : :: :: : :: : :::: :: ::: :: :: :: ::: S79895 TTACAGCAAAGGTGTGTATTATGATGAAAGCTGCAATAGCGATAATCTGAACCATGCGGTTTTGGCAGTGGGATATGGAA 920 930 940 950 960 970 980 990 1150 1160 1170 1180 1190 1200 1210 QUERY T--TGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCT : ::: : : : :: :: : ::: :: : ::::: : :::: : :::::: :: :: :: S79895 TCCAGAAGGGAAACAAGCACTGGATAATTAAAAACAGCTGG-GGAGAA-AACTGGGG-AAACAAAGGATATATCCTCATG 1000 1010 1020 1030 1040 1050 1060 1070 1220 1230 1240 1250 1260 1270 1280 1290 QUERY ACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGA S79895 GCTCGAAATAAGAACAACGCCTGTGGCATTGCCAACCTGGCCAGCTTCCCCAAGATGTGACTCCAGCCAGCCAAATCCAT 1080 1090 1100 1110 1120 1130 1140 1150 --------------------------------------------------------------------------- >>MMPPCATHK X94444 M.musculus mRNA for preprocathepsin K. 1/97 (990 nt) initn: 642 init1: 350 opt: 898 Z-score: 749.4 expect() 7e-35 63.032% identity in 587 nt overlap Entrez lookup Re-search database >MMPPCA 626-1206: -------------------------- : 590 600 610 620 630 640 650 660 QUERY CCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGAAAGGCTACG ::: :::::: :: : :: : :: ::::::: :::: MMPPCA CTACAGTAATGACACTCTCTATACCCCAGAGTGGGAAGGCAGGGTCCCAGACTCCATCGACTATCGAAAGAAAGGATACG 300 310 320 330 340 350 360 370 670 680 690 700 710 720 730 740 QUERY TGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTC : ::::: :::::::: ::::: ::::::::::: ::::::::::: :: :: : :: :: :: :: :: :: : MMPPCA TTACTCCAGTGAAGAACCAGGGCCAGTGTGGTTCCTGTTGGGCTTTCAGCTCTGCCGGGGCCCTGGAGGGCCAACTCAAG 380 390 400 410 420 430 440 450 750 760 770 780 790 800 810 820 QUERY CGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAA ::::::::: : :: : : :::::: :::::::: :: ::::: :: : :: : ::: : ::::: MMPPCA AAGAAAACTGGTAAACTCCTAGCTCTGAGTCCCCAGAATCTTGTGGACTG---TGTGACT---GAGAATTATGGCTGTGG 460 470 480 490 500 510 520 530 830 840 850 860 870 880 890 900 QUERY TGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGG :: ::: ::: ::::::::: :: :: ::: : :: :::::: : :::::::: :: : : ::::::: :: MMPPCA AGGCGGCTATATGACCACTGCTTTCCAATACGTGCAGCAGAACGGAGGCATCGACTCTGAAGATGCTTTCCCATATGTGG 540 550 560 570 580 590 600 610 910 920 930 940 950 960 970 980 QUERY CAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCT---AAGCAG :: ::: :::: ::: :: ::: : : ::::: :: :: : :: :: ::: : : MMPPCA GCCAGGATGAAAGTTGTATGTATAACGCCACGGCAAAGGCAGCTAAATGCAGAGGGTACAGAGAGATTCCTGTGGGGAAC 620 630 640 650 660 670 680 690 990 1000 1010 1020 1030 1040 1050 1060 QUERY GAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTT ::::: ::::::: :: ::::: :: :: :: ::::: ::::: : :: :: ::: : : :: :::: ::: MMPPCA GAGAAAGCCCTGAAGAGAGCAGTGGCGCGGGTAGGACCCATCTCTGTGTCCATCGACGCAAGCTTGGCATCTTTCCAGTT 700 710 720 730 740 750 760 770 1070 1080 1090 1100 1110 1120 1130 QUERY CTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGG-- :: : ::: : :: : ::: : : ::: : :::: : :: : :::: ::: ::::::: ::::: :: MMPPCA TTACAGCAGAGGTGTGTACTATGATGAAAATTGTGACCGTGATAATGTGAACCATGCAGTGTTGGTGGTGGGCTATGGCA 780 790 800 810 820 830 840 850 1140 1150 1160 1170 1180 1190 1200 1210 QUERY ATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCT ::: : : :: :: : ::: :: : ::::: :: : :::::::: :: :: :: MMPPCA CCCAGAAGGGAAGCAAGCACTGGATAATTAAAAACAGCTGGGGA--GAGAGCTGGGG-AAACAAAGGATATGCTCTCTTG 860 870 880 890 900 910 920 930 1220 1230 1240 1250 1260 1270 1280 1290 QUERY ACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGA MMPPCA GCTCGGAATAAGAACAACGCCTGCGGCATTACCAACATGGCCAGCTTCCCCAAGATGTGA 940 950 960 970 980 990 --------------------------------------------------------------------------- >>AF010306 Rattus norvegicus cathepsin K mRNA, complete cds. 8/97 (1248 nt) initn: 605 init1: 341 opt: 887 Z-score: 738.6 expect() 2.2e-34 63.636% identity in 583 nt overlap Entrez lookup Re-search database >AF0103 631-1206: -------------------------- : 600 610 620 630 640 650 660 QUERY GAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGA-TCTGTGGATTGGAGAGAGAAAGGCTACGTGACT :::::: :: : :: : :: :::::::::: :: ::: AF0103 GTAATGACACTCTCTATACCCCAGAGTGGGAAGGCAGAGTCCCAGACTCCATCGACTATCGAAAGAAAGGCTATGTTACT 350 360 370 380 390 400 410 420 670 680 690 700 710 720 730 740 QUERY CCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAA :: :: :: :: ::::: ::::::::::: ::::::::::: :: :: : ::::: :: :: :: :: : ::: AF0103 CCAGTCAAAAACCAGGGCCAGTGTGGTTCCTGTTGGGCTTTCAGCTCTGCGGGTGCCCTGGAGGGCCAACTCAAGAAGAA 430 440 450 460 470 480 490 500 750 760 770 780 790 800 810 820 QUERY AACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTG :::::: : :: : : :::::: :::::::: :: ::::: :: : :: : :: : ::::: :: : AF0103 AACTGGCAAACTCTTAGCTCTGAGTCCCCAGAATCTTGTGGACTG---TGTGTCT---GAGAACTATGGCTGTGGAGGCG 510 520 530 540 550 560 570 580 830 840 850 860 870 880 890 900 QUERY GCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACA :: ::: ::: ::::: ::::: ::: : ::::::::: : :::::::: :: : :: :: :::: :: AF0103 GCTATATGACCACTGCCTTCCAATATGTGCAGCAGAATGGAGGCATTGACTCTGAAGACGCTTACCCGTATGTGGGGCAG 590 600 610 620 630 640 650 660 910 920 930 940 950 960 970 980 QUERY GAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCT---AAGCAGGAGAA :: ::: :::: ::: :: ::: : : ::::: :: :: : :: :::::: : : ::::: AF0103 GATGAAAGTTGTATGTATAACGCCACGGCAAAGGCAGCTAAGTGCAGAGGGTACAGAGAGATCCCTGTGGGGAACGAGAA 670 680 690 700 710 720 730 740 990 1000 1010 1020 1030 1040 1050 1060 QUERY GGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGA-GTCCTTCCTGTTCTAT ::::::: :: ::::: :: :: :: ::: : ::::: : :: :::::: : : ::: :: :::: :: :: AF0103 AGCCCTGAAGAGAGCAGTGGCTCGGGTAGGACCCGTCTCTGTGTCCATCGATGCAAG-CTTGACATCTTTCCAATTTTAC 750 760 770 780 790 800 810 1070 1080 1090 1100 1110 1120 1130 1140 QUERY AAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGG--ATTT : ::: : :: : ::: : :::: : :::: : :: : :::: ::: ::::::: ::::: :: AF0103 AGCAGAGGTGTGTACTATGACGAAAACTGCGACCGTGATAATGTGAACCATGCCGTGTTGGTGGTGGGCTATGGCACCCA 820 830 840 850 860 870 880 890 1150 1160 1170 1180 1190 1200 1210 1220 QUERY GAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGT ::: : : : :: : : ::: :: : ::::: : :::: :::::::: :: :: :: AF0103 GAAGGGAAATAAGTACTGGATAATTAAAAACAGCTGG-GGAGAA-AGCTGGGG-AAACAAAGGCTATGTTCTCTTGGCTC 900 910 920 930 940 950 960 970 1230 1240 1250 1260 1270 1280 1290 1300 QUERY AAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGACGGT AF0103 GGAATAAGAACAATGCCTGTGGCATTACCAACCTGGCCAGCTTCCCCAAGATGTGATTCAAGCCAGCCAGCCCATCTGTT 980 990 1000 1010 1020 1030 1040 1050 --------------------------------------------------------------------------- >>HUMCTSLL3X L25629 Human cathepsin-L-like (CTSLL3) mRNA. 10/93 (208 nt) initn: 766 init1: 455 opt: 829 Z-score: 701.8 expect() 1.5e-31 89.151% identity in 212 nt overlap Entrez lookup Re-search database >HUMCTS 338- 549: ---------: 300 310 320 330 340 350 360 370 QUERY ACACTCATCCTTGCTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGAC :: :::::::: ::: ::::::::::: : ::: ::::: HUMCTS CTGCTCTAACACGTGACCACAGTTTAGATGAACAATGGAC 10 20 30 40 380 390 400 410 420 430 440 450 QUERY CAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGA :::::::::::: : :::::: :::::::: ::::::::::::::::::::::::::::::::::::: ::::::::: HUMCTS CAAGTGGAAGGCAAAGCACAAGAGATTATATGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGG---AGAACATGA 50 60 70 80 90 100 110 460 470 480 490 500 510 520 530 QUERY AGATGATTGAACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATG :::::::::: : : ::::::::::: :::: ::::::::::::::::::::: :::::::::::::::::::::::: HUMCTS AGATGATTGAGCAG-ACAATCAGGAACACAGCCAAGGGAAACACAGCTTCACAACAGCCATGAACGCCTTTGGAGACATG 120 130 140 150 160 170 180 190 540 550 560 570 580 590 600 610 QUERY ACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCT :::: ::::::: HUMCTS ACCACTGAAGAA 200 --------------------------------------------------------------------------- >>HUMCTSLL2X L25628 Human cathepsin-L-like (CTSLL2) mRNA. 10/93 (208 nt) initn: 800 init1: 416 opt: 820 Z-score: 694.2 expect() 3.9e-31 88.679% identity in 212 nt overlap Entrez lookup Re-search database >HUMCTS 338- 549: ---------: 300 310 320 330 340 350 360 370 QUERY ACACTCATCCTTGCTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGAC :: :::::::: ::: :::::: :::: ::::: ::::: HUMCTS CTGCTCTAACACGTGACCACAGTCTAGACGCACAATGGAC 10 20 30 40 380 390 400 410 420 430 440 450 QUERY CAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGA :::::::::::: : :::::: :::::::: : ::::::::::::::::::::::::::::::::: : ::::::::: HUMCTS CAAGTGGAAGGCAAAGCACAAGAGATTATATGACATGAATGAAGAAGGATGGAGGAGAGCAGTGTGAG---AGAACATGA 50 60 70 80 90 100 110 460 470 480 490 500 510 520 530 QUERY AGATGATTGAACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATG :::::: ::: : : :::::::::::::::: :::::::::::::::::::::::::::::::: :::::::::::::: HUMCTS AGATGACTGAGCAG-ACAATCAGGAATACAGCCAAGGGAAACACAGCTTCACAATGGCCATGAACACCTTTGGAGACATG 120 130 140 150 160 170 180 190 540 550 560 570 580 590 600 610 QUERY ACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCT :::: ::::::: HUMCTS ACCACTGAAGAA 200 --------------------------------------------------------------------------- >>BOVCATS M95211 Bovine cathepsin S (catS) mRNA, partial cds. 8/93 (1235 nt) initn: 409 init1: 176 opt: 703 Z-score: 584.7 expect() 8.3e-26 63.077% identity in 455 nt overlap Entrez lookup Re-search database >BOVCAT 691-1139: -------------------- : 660 670 680 690 700 710 720 730 QUERY AGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTG ::::: ::::: :::::::: :::::: :: :: :: : BOVCAT TGTGGCTCTTGCTGGGCTTTCAGTGCTGTGGGAGCCCTGG 10 20 30 40 740 750 760 770 780 790 800 QUERY AAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCT---CTGGGCCTCAA ::: ::: :: : :::::: :: : ::: : :: ::::::: ::::: ::::: :: :::: ::: : BOVCAT AAGCACAAGTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTGAGTGCACAGAACCTGGTGGATTGCTCAACTGCAAAATAT 50 60 70 80 90 100 110 120 810 820 830 840 850 860 870 880 QUERY GGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGA :: ::: ::::::::::::: ::: : ::: : :::::::: ::: : :: :: ::: : :: :: :: : BOVCAT GGGAATAAAGGCTGCAATGGCGGCTTCATGACAGAGGCTTTCCAATATATCATTGACAACAATGGCATCGATTCAGAAGC 130 140 150 160 170 180 190 200 890 900 910 920 930 940 950 960 QUERY ATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTA-ATGACACCGGCTTTGTG :::::::: :: : :: : :: : : :: :::: :: :: :: : ::: : :: :: : :: BOVCAT TTCCTATCCCTACAAAGCCATGGATGGAAAGTGCCAGTATGATGTAAAAAATCGAGCTGCCACGTGTTCAAGGTATATTG 210 220 230 240 250 260 270 280 970 980 990 1000 1010 1020 1030 1040 QUERY GACATCCC-TAAGCAG-GAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGT :: :::: : :::: :: ::::: : : : :: :: :: : : :: :: : ::::::: ::: :: :: : BOVCAT AACTTCCCTTCGGCAGCGAAGAGGCCTTAAAAGAAGCCGTGGCCAATAAAGGACCTGTGTCTGTTGGTATAGACGCGAGC 290 300 310 320 330 340 350 360 1050 1060 1070 1080 1090 1100 1110 1120 QUERY CATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCT ::: :: ::: : :::: ::: :: : :: : ::: :: :: ::: : : : :: : :::::::: :: BOVCAT CATTCTTCTTTCTTCCTCTACAAAACTGGTGTCTACTATGACCC---CTCCTGCACTCAGAATGTGAACCATGGTGTACT 370 380 390 400 410 420 430 1130 1140 1150 1160 1170 1180 1190 1200 QUERY GGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAAT ::::::::::: :: BOVCAT CGTGGTTGGCTATGGTAACCTTGACGGGAAGGACTACTGGCTTGTGAAAAACAGCTGGGGCCTGCACTTTGGTGACCAAG 440 450 460 470 480 490 500 510 --------------------------------------------------------------------------- >>BTCATPS X62001 B.taurus mRNA for cathepsin S. 6/93 (1234 nt) initn: 409 init1: 176 opt: 703 Z-score: 584.7 expect() 8.3e-26 63.077% identity in 455 nt overlap Entrez lookup Re-search database >BTCATP 691-1139: -------------------- : 660 670 680 690 700 710 720 730 QUERY AGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTG ::::: ::::: :::::::: :::::: :: :: :: : BTCATP TGTGGCTCTTGCTGGGCTTTCAGTGCTGTGGGAGCCCTGG 10 20 30 40 740 750 760 770 780 790 800 QUERY AAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCT---CTGGGCCTCAA ::: ::: :: : :::::: :: : ::: : :: ::::::: ::::: ::::: :: :::: ::: : BTCATP AAGCACAAGTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTGAGTGCACAGAACCTGGTGGATTGCTCAACTGCAAAATAT 50 60 70 80 90 100 110 120 810 820 830 840 850 860 870 880 QUERY GGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGA :: ::: ::::::::::::: ::: : ::: : :::::::: ::: : :: :: ::: : :: :: :: : BTCATP GGGAATAAAGGCTGCAATGGCGGCTTCATGACAGAGGCTTTCCAATATATCATTGACAACAATGGCATCGATTCAGAAGC 130 140 150 160 170 180 190 200 890 900 910 920 930 940 950 960 QUERY ATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTA-ATGACACCGGCTTTGTG :::::::: :: : :: : :: : : :: :::: :: :: :: : ::: : :: :: : :: BTCATP TTCCTATCCCTACAAAGCCATGGATGGAAAGTGCCAGTATGATGTAAAAAATCGAGCTGCCACGTGTTCAAGGTATATTG 210 220 230 240 250 260 270 280 970 980 990 1000 1010 1020 1030 1040 QUERY GACATCCC-TAAGCAG-GAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGT :: :::: : :::: :: ::::: : : : :: :: :: : : :: :: : ::::::: ::: :: :: : BTCATP AACTTCCCTTCGGCAGCGAAGAGGCCTTAAAAGAAGCCGTGGCCAATAAAGGACCTGTGTCTGTTGGTATAGACGCGAGC 290 300 310 320 330 340 350 360 1050 1060 1070 1080 1090 1100 1110 1120 QUERY CATGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCT ::: :: ::: : :::: ::: :: : :: : ::: :: :: ::: : : : :: : :::::::: :: BTCATP CATTCTTCTTTCTTCCTCTACAAAACTGGTGTCTACTATGACCC---CTCCTGCACTCAGAATGTGAACCATGGTGTACT 370 380 390 400 410 420 430 1130 1140 1150 1160 1170 1180 1190 1200 QUERY GGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAAT ::::::::::: :: BTCATP CGTGGTTGGCTATGGTAACCTTGACGGGAAGGACTACTGGCTTGTGAAAAACAGCTGGGGCCTGCACTTTGGTGACCAAG 440 450 460 470 480 490 500 510 --------------------------------------------------------------------------- >>HSCATLR1 X05256 Human mRNA fragment for cathepsin L N-terminal/fragment. 4/ (126 nt) initn: 630 init1: 630 opt: 630 Z-score: 538.4 expect() 3.1e-22 100.000% identity in 126 nt overlap Entrez lookup Re-search database >HSCATL 625- 750: -----: 590 600 610 620 630 640 650 660 QUERY GCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTGGATTGGAGAGAGAAAGGCTACG :::::::::::::::::::::::::::::::::::::::: HSCATL GAGGCCCCCAGATCTGTGGATTGGAGAGAGAAAGGCTACG 10 20 30 40 670 680 690 700 710 720 730 740 QUERY TGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: HSCATL TGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTC 50 60 70 80 90 100 110 120 750 760 770 780 790 800 810 820 QUERY CGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAGGCTGCAA :::::: HSCATL CGGAAA --------------------------------------------------------------------------- >>SSAF001169 AF001169 Sus scrofa preprocathepsin H mRNA, complete cds. 1/98 (1149 nt) initn: 179 init1: 113 opt: 574 Z-score: 477.1 expect() 8.7e-20 56.283% identity in 764 nt overlap Entrez lookup Re-search database >SSAF00 485-1223: -------------------------------- : 450 460 470 480 490 500 510 520 QUERY GAGAAGAACATGAAGATGATTGAACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGC ::: : ::::: :::: :: : : ::: ::::: SSAF00 CTGCAGGTGTTTGTCAGCAACTGGAGGAAGATCAATGCCCACAACGCTGGGAACCACACATTTAAACTGGGACTGAACCA 190 200 210 220 230 240 250 260 530 540 550 560 570 580 590 QUERY CTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTG-ATGAATGG-----CTTTCAAAACCG-TAAGCCCAGGAAGGGG ::: :::::::: : ::: ::: : :: :: : :: ::: ::: :: : : :::: :::: SSAF00 ATTTTCAGACATGAGCTTTGATGAAATAAGACACAAGTATCTTTGGTCAGAGCCTCAGAATTGTTCAGCCACCAAAGGTA 270 280 290 300 310 320 330 340 600 610 620 630 640 650 660 670 QUERY AAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTGGATTGGAGAGAGAAAGG---CTACGTGACTCCTGT : : : :: ::: : : : : ::: ::: :::: ::: : : ::::: : :: : :: :: SSAF00 ACTACCTGCGGGGTACCGGTCCCT----ACCCACCC---TCTATGGACTGGCGGAAAAAAGGAAATTTTGTCTCACCAGT 350 360 370 380 390 400 410 420 680 690 700 710 720 730 740 750 QUERY GAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTT--CCGGAAAAC ::: :::::::: :: :: ::: ::: : :: : : :: :: :: :::: : : : : :::: : ::: SSAF00 GAAAAATCAGGGCAGCTGCGGCAGTTGCTGGACCTTCTCTACCACAGGGGC-CTTGGA-GTCTGCTGTTGCCATCGCAAC 430 440 450 460 470 480 490 760 770 780 790 800 810 820 830 QUERY TGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACT--GCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGG ::::: : : : :: :: :: ::: : ::::: :::: :: : : : :::: :::: : :::::: : :: :: SSAF00 TGGGAAGATGCTGTCCTTGGCAGAACAGCAGCTGGTGGACTGCGCCCAGAACTTCAA--CAATCACGGCTGCCAAGGGGG 500 510 520 530 540 550 560 570 840 850 860 870 880 890 900 910 QUERY CCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAG :: : :: ::: :::: : : : :: ::: : ::: :: :::: :: :: ::: : SSAF00 TCTCCCCAGCCAGGCCTTCGAGTACATCCGCTACAACAAGGGCATCATGGGTGAAGACACCTACCCGTACAAGGGCCAGG 580 590 600 610 620 630 640 650 920 930 940 950 960 970 980 QUERY AAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCC---TAAGCAGGAGAAG : :: ::: :::: : : ::: : : : ::::: :: :: : : : ::::: : :: : ::: :: SSAF00 ATGATCACTGCAAGTTCCAGCCCGATAAGGCCATTGCTTTTGTCAAGGATGTAGCCAACATCACAATGAATGACGAGGAG 660 670 680 690 700 710 720 730 990 1000 1010 1020 1030 1040 1050 1060 QUERY GCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATT--TCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTTCTAT :: :: :: :::: :: :: :::: ::: : :: :::: : :: : : :::: ::: :: : :: SSAF00 GCGATGGTGGAGGCGGTGGC-CCTGTACAACCCTGTGAGCT-TTGCCTTCGAGGTGACTAATGA---CTTTCTCATGTAC 740 750 760 770 780 790 800 810 1070 1080 1090 1100 1110 1120 1130 QUERY AAAGAAGGCATTTATTTTGAGCCAGACTG---TAGCAGTGAAGACA---TGGATCATGGTGTGCTGGTGGTTGGCTACGG : : : ::::: :: : : ::: :: : : ::: : : : :: : :: :::: ::::: ::::: SSAF00 AGAAAGGGCATCTACTCCAGTACCTCCTGCCATAAAACTCCAGATAAAGTCAACCACGCAGTACTGGCTGTTGGGTACGG 820 830 840 850 860 870 880 890 1140 1150 1160 1170 1180 1190 1200 1210 QUERY ATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCT :: : : ::: :::: : ::::::: : ::::: ::: :::::: : ::::: ::: ::: : SSAF00 -------AGAAGAAAATGGGATACC-----ATATTGGATTGTGAAAAACTCATGGGGTCCCCAGTGGGGAATGAATGGGT 900 910 920 930 940 950 960 1220 1230 1240 1250 1260 1270 1280 1290 QUERY ACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGA :: : SSAF00 ACTTCCTCATCGAGCGTGGAAAGAACATGTGCGGCCTGGCCGCCTGCGCCTCCTACCCGATCCCCCTGGTGTGAGCCAGG 970 980 990 1000 1010 1020 1030 1040 --------------------------------------------------------------------------- >>HSCATHH X16832 Human mRNA for cathepsin H (EC 3.4.22.16). 3/95 (1399 nt) initn: 143 init1: 82 opt: 513 Z-score: 424.8 expect() 5.9e-17 54.600% identity in 837 nt overlap Entrez lookup Re-search database >HSCATH 485-1294: ------------------------------------ : 450 460 470 480 490 500 510 520 QUERY GAGAAGAACATGAAGATGATTGAACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGC ::: : ::::: :::: :: : :::::: ::::: HSCATH CTGCAGACGTTTGCCAGCAACTGGAGGAAGATAAACGCCCACAACAATGGGAACCACACATTTAAAATGGCACTGAACCA 200 210 220 230 240 250 260 270 530 540 550 560 570 580 590 QUERY CTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTG-ATGAATGG-----CTTTCAAAACCG-TAAGCCCAGGAAGGGG ::: :::::::: : :: ::: : : :: : :: ::: ::: :: : : :::: :: : HSCATH ATTTTCAGACATGAGCTTTGCTGAAATAAAACACAAGTATCTCTGGTCAGAGCCTCAGAATTGCTCAGCCACCAAAAGTA 280 290 300 310 320 330 340 350 600 610 620 630 640 650 660 670 QUERY AAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTGGATTGGAGAGAGAAAGG---CTACGTGACTCCTGT : ::: ::: : ::: : : ::: :: ::::: ::: : : ::::: : :: : ::::: HSCATH ACTACCTTCGAGGTA---CTGGTCCCT----ACCCACCTTCCGTGGACTGGCGGAAAAAAGGAAATTTTGTCTCACCTGT 360 370 380 390 400 410 420 680 690 700 710 720 730 740 750 QUERY GAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACTG ::: ::::::::: :: :: ::: ::: :::: : ::::: :: :: :: :: : ::: : HSCATH GAAAAATCAGGGTGCCTGCGGCAGTTGCTGGACTTTCTCCACCACTGGGGCCCTGGAGTCTGCAATCGCCATCGCAACCG 430 440 450 460 470 480 490 500 760 770 780 790 800 810 820 830 QUERY GGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACT--GCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCC : : : : : :: :: :: ::: : ::::: :::: :: : :: : :::: ::: : :::::: : :: :: : HSCATH GAAAGATGCTGTCCTTGGCGGAACAGCAGCTGGTGGACTGCGCCCAGGACTTCAA--TAATTACGGCTGCCAAGGGGGTC 510 520 530 540 550 560 570 580 840 850 860 870 880 890 900 910 QUERY TAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAGAA : : :::::: ::::: : : : : :: :: : ::: :: :::: :: :: ::: : :: HSCATH TCCCCAGCCAGGCTTTCGAGTATATCCTGTACAACAAGGGGATCATGGGTGAAGACACCTACCCCTACCAGGGCAAGGAT 590 600 610 620 630 640 650 660 920 930 940 950 960 970 980 QUERY GAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTA---AGCAGGAGAAGGC : : :: :::: : : :: : : : : :: :: : : : ::::: : : : : ::: : :: HSCATH GGTTATTGCAAGTTCCAACCTGGAAAGGCCATCGGCTTTGTCAAGGATGTAGCCAACATCACAATCTATGACGAGGAAGC 670 680 690 700 710 720 730 740 990 1000 1010 1020 1030 1040 1050 1060 QUERY CCTGATGAAGGCAGTTGCAACTGTGGGGCCCATT--TCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATAA :: :: :::: :: :: :: : ::: : :: :::: :::: : ::: :: :::: :: : :::: HSCATH GATGGTGGAGGCTGTGGC-CCTCTACAACCCTGTGAGCT-TTGCCTTTGAGGTGACTCAGGA---CTTCATGATGTATAG 750 760 770 780 790 800 810 820 1070 1080 1090 1100 1110 1120 1130 1140 QUERY AGAAGGCATTTATTTTGAGCCAGACTG---TAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATTTG : ::::: :: : : ::: :: : : ::: : : : :: : ::: :: :: : :: HSCATH AACGGGCATCTACTCCAGTACTTCCTGCCATAAAACTCCAGATAAAGTAAACCATGCAGTACTGGCTG---TTGGGTATG 830 840 850 860 870 880 890 1150 1160 1170 1180 1190 1200 1210 1220 QUERY AAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTA :: : : ::: ::: : :: ::: : ::::: ::: :::::: : ::::: ::: :: ::: : HSCATH -GAGAAAAAAATGGGATCCC-----TTACTGGATCGTGAAAAACTCTTGGGGTCCCCAGTGGGGAATGAACGGGTACTTC 900 910 920 930 940 950 960 970 1230 1240 1250 1260 1270 1280 1290 QUERY AAGATGGCCAAAGACCGGAGAAACCAT-TGTGGAATTGCCTCAGCAGCCAGCTACCCCA-----CT-GTGTGAGCTGGTG :: : :: :::: : : ::: ::::: : :: : ::: :::::::: :: :::::::: : HSCATH CTCATCG----AGCGCGGAAAGAACATGTGTGGCCTGGCTGCCTGCGCCTCCTACCCCATCCCTCTGGTGTGAGCCGTGG 980 990 1000 1010 1020 1030 1040 1300 1310 1320 1330 1340 1350 1360 1370 QUERY GACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCAGTCTACCAGCCCCCGCTGTG HSCATH CAGCCGCAGCGCAGACTGGCGGAGAAGGAGAGGAACGGGCAGCCTGGGCCTGGGTGGAAATCCTGCCCTGGAGGAAGTTG 1050 1060 1070 1080 1090 1100 1110 1120 --------------------------------------------------------------------------- >>MMCTSH U06119 Mus musculus cathepsin H prepropeptide (ctsH) mRNA, complete (1381 nt) initn: 84 init1: 84 opt: 475 Z-score: 393.0 expect() 3.5e-15 55.414% identity in 785 nt overlap Entrez lookup Re-search database >MMCTSH 471-1223: --------------------------------- : 440 450 460 470 480 490 500 510 QUERY GGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACA : : : ::: : ::: : :::: :::: :: : : MMCTSH AGTACAACCACAGACTGCAGATGTTTGCCAACAACTGGAGGAAGATTCAAGCCCACAACCAGAGGAACCACACATTTAAA 190 200 210 220 230 240 250 260 520 530 540 550 560 570 580 QUERY ATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTT---TCAAAACCGTA---- ::::: ::::: ::: ::: :::: : :: ::: : : : : ::: ::: ::: : :: : MMCTSH ATGGCGTTGAACCAGTTTTCAGATATGAGCTTTGCTGAAATAAAAC-----ACAAATTCCTTTGGTCAGAGCCTCAGAAT 270 280 290 300 310 320 330 340 590 600 610 620 630 640 650 QUERY AGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCA-----GATCTGTGGATTGGAGAGAGAAAG :: ::: : ::::: : ::::: : :: ::::::: : :: :::: ::::: :::::: MMCTSH TGCTCAGCCA-CCAAAAGT-----AACTACCTCCGAGGTA-CAGGCCCCTACCCTTCCTCCATGGACTGGAGGAAGAAAG 350 360 370 380 390 400 410 660 670 680 690 700 710 720 730 QUERY GCTA---CGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGA : : :: : :: ::::: :::::::: :::: :: ::: :::: : : :: :: :: :: :: : MMCTSH GAAATGTTGTTTCGCCAGTGAAAAATCAGGGGGCCTGTGCGAGCTGCTGGACTTTCTCTACCACGGGGGCCCTAGA--GT 420 430 440 450 460 470 480 490 740 750 760 770 780 790 800 810 QUERY CAGATGTTCC--GGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGA--CTGCTCTGGGCCTCAAGGCA ::: ::: : : ::::: : : :: :: ::::::: : ::::: :: ::: : : : :::: :: MMCTSH CAGCTGTGGCTATTGCCAGTGGGAAAATGCTGTCTTTGGCTGAGCAGCAGCTGGTGGATTGTGCCCAAGCCTTCAA--CA 500 510 520 530 540 550 560 570 820 830 840 850 860 870 880 890 QUERY ATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCC :: : :::::::: :: :: :: : :: ::: :::: : : : :: ::: : :: :: : MMCTSH ATCATGGCTGCAAAGGAGGTCTCCCCAGCCAGGCCTTCGAGTACATCCTATACAACAAGGGCATCATGGAAGAAGACAGC 580 590 600 610 620 630 640 650 900 910 920 930 940 950 960 970 QUERY TATCCATA-TGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACA :: :: :: :::::: :: :: :: : : ::: ::: : : ::::::: : :: :::: ::: MMCTSH TACCCTTACATAGGCAA-GGATAGTTCATGCAGATTCAACCCCCAAAAAGCTGTTGCATTCGTCAAGAATGTTGTCAACA 660 670 680 690 700 710 720 730 980 990 1000 1010 1020 1030 1040 QUERY TC---CCTAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTT-GCTATTGATGCAGGTCA :: : :: : ::: :: :: : :::: :: :: :: : ::: : :: :: ::: :::: : MMCTSH TCACACTCAATGACGAGGCTGCAATGGTTGAGGCTGTGGC-TCTATACAACCCTGTGAGCTTCGCCTTTG----AGGTGA 740 750 760 770 780 790 800 1050 1060 1070 1080 1090 1100 1110 QUERY -TGAGTCCTTCCTGTTCTATAAAGAAGGCATTTATT----TTGAGCCAGACTGTAGCAGTGAAGACA---TGGATCATGG ::: :: :: : :::::: ::: : :: : : : :: : : :: : : ::: : : : :::: MMCTSH CTGAAGATTTTTTGATGTATAAAAGTGGCGTCTACTCCAGTAAATCCTGTC-ATAAAACTCCAGATAAAGTAAACCATGC 810 820 830 840 850 860 870 880 1120 1130 1140 1150 1160 1170 1180 1190 QUERY TGTGCTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTG :: :::: ::::::::: :: :: ::::::: ::: :: :: ::: : ::::: ::: ::::: MMCTSH AGTCCTGGCGGTTGGCTATGG-------AGAACAGAAT-GGATTAC----TCTACTGGATTGTGAAAAACTCTTGGGGCT 890 900 910 920 930 940 950 1200 1210 1220 1230 1240 1250 1260 1270 QUERY AAGAATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTAC : ::::: : ::: ::: : MMCTSH CCCAGTGGGGGGAGAATGGGTACTTCCTCATTGAACGTGGGAAGAACATGTGTGGCCTGGCTGCTTGTGCCTCCTATCCC 960 970 980 990 1000 1010 1020 1030 --------------------------------------------------------------------------- >>HSCATHEP5 U07373 Human cathepsin S gene, exon 5, partial cds. 8/94 (461 nt) initn: 349 init1: 194 opt: 463 Z-score: 390.2 expect() 1.5e-14 67.391% identity in 230 nt overlap Entrez lookup Re-search database >HSCATH 681- 907: ---------- : 650 660 670 680 690 700 710 720 QUERY TGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACT : ::::: :::::: :::: :::::::: :::::: HSCATH ATGATTTTCTGTGATTTGCGTTTGTGACCTTGTATCTGTTTTAGGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTG 110 120 130 140 150 160 170 180 730 740 750 760 770 780 790 QUERY GGTGCTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCT---C :: :: :: :::: :::: :: : :::::: :: : ::: : : :: :::: ::::: ::::: :: :::: : HSCATH GGGGCCCTGGAAGCACAGCTGAAGCTGAAAACAGGAAAGCTGGTGACTCTCAGTGCCCAGAACCTGGTGGATTGCTCAAC 190 200 210 220 230 240 250 260 800 810 820 830 840 850 860 870 QUERY TGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGG :: : :: :: ::::::::::::::::: : ::: ::::::::::: : ::::: ::: : : HSCATH TGAAAAATATGGAAACAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCG 270 280 290 300 310 320 330 340 880 890 900 910 920 930 940 950 QUERY ACTCTGAGGAATCCTATCCATATGAGGCAACAGAAGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACC :::: :: : :::::::: :: : :: : HSCATH ACTCAGACGCTTCCTATCCCTACAAAGCCATGGTGCGTCTTAAGCAAACTTTTTTTTCTGCCCCATGATCTCATGTTATC 350 360 370 380 390 400 410 420 --------------------------------------------------------------------------- >>HSCATH X07549 Human mRNA for cathepsin H (E.C.3.4.22.16.). 11/92 (1106 nt) initn: 81 init1: 81 opt: 456 Z-score: 378.6 expect() 2.8e-14 55.721% identity in 603 nt overlap Entrez lookup Re-search database >HSCATH 637-1223: -------------------------- : 600 610 620 630 640 650 660 670 QUERY GAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTGGATTGGAGAGAGAAAGG---CTACGTGACTCCTG :: ::::: ::: : : ::::: : :: : :::: HSCATH CAAAAGTAACTACCTTCGAGGTACTGGTCCCTACCCACCTTCCGTGGACTGGCGGAAAAAAGGAAATTTTGTCTCACCTG 60 70 80 90 100 110 120 130 680 690 700 710 720 730 740 750 QUERY TGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTTCCGGAAAACT :::: ::::::::: :: :: ::: ::: :::: : ::::: :: :: :: :: : ::: HSCATH TGAAAAATCAGGGTGCCTGCGGCAGTTGCTGGACTTTCTCCACCACTGGGGCCCTGGAGTCTGCAATCGCCATCGCAACC 140 150 160 170 180 190 200 210 760 770 780 790 800 810 820 830 QUERY GGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACT--GCTCTGGGCCTCAAGGCAATGAAGGCTGCAATGGTGGC :: : : : : :: :: :: ::: : ::::: :::: :: : :: : :::: ::: : :::::: : :: :: HSCATH GGAAAGATGCTGTCCTTGGCGGAACAGCAGCTGGTGGACTGCGCCCAGGACTTCAA--TAATTACGGCTGCCAAGGGGGT 220 230 240 250 260 270 280 290 840 850 860 870 880 890 900 910 QUERY CTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCATATGAGGCAACAGA :: : :::::: ::::: : : : : :: :: : ::: :: :::: :: :: ::: : :: HSCATH CTCCCCAGCCAGGCTTTCGAGTATATCCTGTACAACAAGGGGATCATGGGTGAAGACACCTACCCCTACCAGGGCAAGGA 300 310 320 330 340 350 360 370 920 930 940 950 960 970 980 QUERY AGAATCCTGTAAGTACAATCCCAAGTATTCTGTTGCTAATGACACCGGCTTTGTGGACATCCCTA---AGCAGGAGAAGG : : :: :::: : : :: : : : : :: :: : : : ::::: : : : : ::: : : HSCATH TGGTTATTGCAAGTTCCAACCTGGAAAGGCCATCGGCTTTGTCAAGGATGTAGCCAACATCACAATCTATGACGAGGAAG 380 390 400 410 420 430 440 450 990 1000 1010 1020 1030 1040 1050 1060 QUERY CCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATT--TCTGTTGCTATTGATGCAGGTCATGAGTCCTTCCTGTTCTATA : :: :: :::: :: :: :: : ::: : :: :::: :::: : ::: :: :::: :: : :::: HSCATH CGATGGTGGAGGCTGTGGC-CCTCTACAACCCTGTGAGCT-TTGCCTTTGAGGTGACTCAGGA---CTTCATGATGTATA 460 470 480 490 500 510 520 1070 1080 1090 1100 1110 1120 1130 1140 QUERY AAGAAGGCATTTATTTTGAGCCAGACTG---TAGCAGTGAAGACA---TGGATCATGGTGTGCTGGTGGTTGGCTACGGA : ::::: :: : : ::: :: : : ::: : : : :::: :: :::: ::::: :: ::: HSCATH GAACGGGCATCTACTCCAGTACTTCCTGCCATAAAACTCCAGATAAAGTAAACCATGCAGTACTGGCTGTTGGGTATGGA 530 540 550 560 570 580 590 600 1150 1160 1170 1180 1190 1200 1210 1220 QUERY TTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTA :::: : ::: ::: : :: ::: : ::::: ::: :::::: : ::::: ::: :: :: HSCATH ---GAAA----AAAATGGGATCCC-----TTACTGGATCGTGAAAAACTCTTGGGGTCCCCAGTGGGGAATGAACGGGTA 610 620 630 640 650 660 670 1230 1240 1250 1260 1270 1280 1290 1300 QUERY CGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGAC : : HSCATH CTTCCTCATCGAGCGCGGAAAGAACATGTGTGGCCTGGCTGCCTGCGCCTCCTACCCCATCCCTCTGGTGTGAGCCGTGG 680 690 700 710 720 730 740 750 --------------------------------------------------------------------------- >>MMCTLA2A X15591 Mouse ctla-2-alpha mRNA, homolog. to cysteine protease pror (664 nt) initn: 390 init1: 390 opt: 422 Z-score: 353.4 expect() 1.2e-12 60.058% identity in 343 nt overlap Entrez lookup Re-search database >MMCTLA 269- 609: --------------- : 230 240 250 260 270 280 290 300 QUERY CGCGTGACTGGTTGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGTTTTAAAACATGAATCCTACACTCATCCT ::: ::: : : : : :: : : : :: :: :::: MMCTLA AAAATGATGGTTTCTATCTGTGAACAGAAGCTGCAGCACTTCAGTGCT---GTCTTCCT 10 20 30 40 50 310 320 330 340 350 360 370 380 QUERY TGCTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGG : : ::: ::::::: :::::: ::: : : ::::: ::::: :: :::::: : :::::: MMCTLA GCTCATCCTCTGCTTGGGAATGATGTCAGCTGCTCCACCCCCTGATCCAAGTTTGGATAATGAGTGGAAAGAATGGAAGA 60 70 80 90 100 110 120 130 390 400 410 420 430 440 450 460 QUERY CG--ATGCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTG :: :: ::: :: ::: ::::::::::: :: :: ::: ::::::::: :::: : ::::: :::: MMCTLA CGAAATTTGCAAAAG--CCTACAATCTGAATGAAGAAAGACACAGAAGACTCGTGTGGGAGGAGAATAAGAAGAAAATTG 140 150 160 170 180 190 200 210 470 480 490 500 510 520 530 540 QUERY AACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAA : :::::: :: :: : : :: :: ::::::: :::: : :::: ::: : ::: :::: ::: MMCTLA AGGCACACAATGCAGACTATGAGCAGGGCAAGACCAGCTTCTACATGGGCCTGAATCAATTTAGTGACTTGACTCCAGAA 220 230 240 250 260 270 280 290 550 560 570 580 590 600 610 620 QUERY GAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGA ::::::: :: ::: ::: : :::: : : : ::: :::: : ::: : MMCTLA GAATTCA------AGACAAATTGCTATGGAAAC--TCACTGAATAGAGGAGAAATGGCTCCTGATTTGCCTGAATATGAA 300 310 320 330 340 350 360 630 640 650 660 670 680 690 700 QUERY GGCCCCCAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGG MMCTLA GATTTGGGAAAGAACAGCTATCTGACACCTGGAAGGGCTCAGCCAGAGTAACAGCTGTGGCTTGACTGGTAACAATAGCA 370 380 390 400 410 420 430 440 --------------------------------------------------------------------------- >>MMCTLA2B X15592 Mouse ctla-2-beta mRNA, homolog. to cysteine protease prore (777 nt) initn: 373 init1: 373 opt: 404 Z-score: 337.3 expect() 7.9e-12 59.475% identity in 343 nt overlap Entrez lookup Re-search database >MMCTLA 269- 609: --------------- : 230 240 250 260 270 280 290 300 QUERY CGCGTGACTGGTTGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGTTTTAAAACATGAATCCTACACTCATCCT ::: ::: : : : : :: : : : :: :: :::: MMCTLA CTGGACAACAAAGTTCTGGTTTCTATCTGTGAACAGAAGCTGCAGCACTTCAGTGCT---GTCTTCCT 10 20 30 40 50 60 310 320 330 340 350 360 370 380 QUERY TGCTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGG : : ::: ::::::: :::::: ::: : : ::::: ::::: :: :::::: : :::::: MMCTLA GCTCATCCTCTGCTTGGGAATGATGTCAGCTGCTCCATCCCCTGATCCAAGTTTGGATAATGAGTGGAAAGAATGGAAGA 70 80 90 100 110 120 130 140 390 400 410 420 430 440 450 460 QUERY C--GATGCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTG : :: ::: :: ::: : :: :::::::: :: :: ::: :::::::: :::: : ::::: :::: MMCTLA CAACATTTGCAAAAG--CCTACAGTCTGGATGAAGAAAGACACAGAAGACTCATGTGGGAGGAGAATAAGAAGAAAATTG 150 160 170 180 190 200 210 220 470 480 490 500 510 520 530 540 QUERY AACTGCACAATCAGGAATACAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAA : :::::: :: :: : :: :: ::::::: :::: : :::: ::: : ::: :::: ::: MMCTLA AGGCACACAATGCAGACTATGAGCGGGGCAAGACCAGCTTCTACATGGGCCTGAATCAATTTAGTGACTTGACTCCAGAA 230 240 250 260 270 280 290 300 550 560 570 580 590 600 610 620 QUERY GAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGA :::::::: :: ::: ::: : :: : : : :: ::: :::: : ::: : MMCTLA GAATTCAG------GACAAATTGCTGTGGAAGCTCAATGTGTAG--AGGAGAAATGGCTCCTGATTTGCCTGAATATGAA 310 320 330 340 350 360 370 630 640 650 660 670 680 690 700 QUERY GGCCCCCAGATCTGTGGATTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGG MMCTLA GATTTGGGAAAGAACAGCTATCTGACACCTGGAAGGGCTCAGCCAGAGTAACAGTTGTGGCTTGACTGGTAACAATATCA 380 390 400 410 420 430 440 450 --------------------------------------------------------------------------- >>AF025476 Rattus norvegicus cathepsin L gene, partial cds. 10/97 (3198 nt) initn: 190 init1: 190 opt: 347 Z-score: 280.4 expect() 2.8e-09 72.535% identity in 142 nt overlap Entrez lookup Re-search database >AF0254 274- 414: ------ : 240 250 260 270 280 290 300 310 QUERY GACTGGTTGAGCGGGCAGGCCAGCCTCCGAGCCGGGTGGACACAGGT-TTTAAAACATGAATCCTACACTCATCCTTGCT : ::::: ::: :: ::::: ::: :::: :::: ::: AF0254 AAGGCTTCGTGGGATCCTCATTTCCTCTTCTTTTTCCTTCCCCAGGTGTTTGAACCATGACCCCTTTACTCCTCCTGGCT 2980 2990 3000 3010 3020 3030 3040 3050 320 330 340 350 360 370 380 390 QUERY GCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGAT : : : ::: :::::: :::: ::: :::: :: ::::::::: : :: : ::::::::: : :::::::: : : AF0254 GTCCTCTGCTTGGGAACAGCCTTAGCCACTCCAAAATTTGATCAAACGTTTAATGCACAGTGGCACCAGTGGAAGTCCAC 3060 3070 3080 3090 3100 3110 3120 3130 400 410 420 430 440 450 460 470 QUERY GCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGC :::: ::: : :: :::: : AF0254 ACACAGAAGACTGTATGGCACGGTTTGTAGTATTTACATTGTCTAGAGAGAATGGTCTTCCTTCC 3140 3150 3160 3170 3180 3190 --------------------------------------------------------------------------- >>MMTSP X17071 Mouse mRNA for a trophoblast-specific protein. 3/95 (707 nt) initn: 297 init1: 160 opt: 273 Z-score: 228.3 expect() 1e-05 55.352% identity in 327 nt overlap Entrez lookup Re-search database >MMTSP 366- 691: --------------- : 330 340 350 360 370 380 390 400 QUERY GAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGGCACAGTGGACCAAGTGGAAGGCGATGCACAACAGATTA : :: ::: ::: : : ::::: ::: : : MMTSP AATCTTCCTAGTCATCCTATGCCTGGGAGTGGCCTCAGCTGTCATAGTCCCTGAAGCGCAGTTGGATGCTGAACTG-CAA 90 100 110 120 130 140 150 160 410 420 430 440 450 460 470 480 QUERY TACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAACATGAAGATGATTGAACTGCACAATCAGGAATA : : : :: :::::: : : :::::::::: ::: ::::::: : :::: :::: : ::: : MMTSP GAGCAGAAGGATAAAGAAGTTCTCATAAAAGCAGTGTGGAGTAAGTTTATGAAGACTAACAAACTTCACAGTAGCGAAAA 170 180 190 200 210 220 230 240 490 500 510 520 530 540 550 560 QUERY CAGGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGA : : :: : ::: :: :: : :::: :::: :: : : :: ::::::: ::: : : : :::: MMTSP TGACCAGGAGACGGAAGGCTCCAACATAGAAATGAGTGCCTCCGGTCAGCTAACTGATGAAGAACTCATGAAAATAATGA 250 260 270 280 290 300 310 320 570 580 590 600 610 620 630 640 QUERY ATGGCTTTCAAAACCGTAAG-CCCAGGAAGGGGAAAGTGTTCCAGGAACCTCTGTTTTATGAGGCCCCCAGATCTGTGGA : :: : ::: : : : :: : ::::: ::: : :: : :: :::: ::: :: :: ::: MMTSP CTACTGTTTTACACCCAATGTTTGAAGAGGAGGAAAACAAACCA-CAGCCAGTTGTTGATGA---CCCTGAATTTGAGGA 330 340 350 360 370 380 390 400 650 660 670 680 690 700 710 720 QUERY TTGGAGAGAGAAAGGCTACGTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTG :: : ::::: ::: : : : : ::: :::::: :::: MMTSP TTACACAGAGAGTGGCGATGGGTTTTTTGTACCAAATCAGCCACAGTAACATGGACAGCAGTATGAAGTTAGGCAACGAG 410 420 430 440 450 460 470 480 730 740 750 760 770 780 790 800 QUERY CTCTTGAAGGACAGATGTTCCGGAAAACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCT MMTSP CGAAACAGCCACTGTGCCATTGTCTAAGAAATCTCTGCCCCAACATATGAACTGCCTGATGGTGAAAAAGAAGATCTGAA 490 500 510 520 530 540 550 560 --------------------------------------------------------------------------- >>HSCATHCGE X87212 H.sapiens mRNA for cathepsin C. 11/95 (1838 nt) initn: 128 init1: 81 opt: 208 Z-score: 167.6 expect() 0.0095 55.749% identity in 287 nt overlap Entrez lookup Re-search database >HSCATH 1015-1284: ------------ : 980 990 1000 1010 1020 1030 1040 1050 QUERY TAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCT :::::::: : :::::: :::: : : : :::: : : HSCATH CTGCAATGAAGCCCTGATGAAGCTTGAGTTGGTCCATCATGGGCCCATGGCAGTTGCTTTTGAAGTATATGATGACTTCC 1100 1110 1120 1130 1140 1150 1160 1170 1060 1070 1080 1090 1100 1110 1120 QUERY TCCTGTTCTATAAAG---------AAGGCATTTATTT---TGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTG ::: : : : :: : : :: : : : :: :: : : ::: : :::::: ::: HSCATH TCCACTACAAAAAGGGGATCTACCACCACACTGGTCTAAGAGACCCTTTCAACCCCTTTGAGCTGACTAATCATGCTGTT 1180 1190 1200 1210 1220 1230 1240 1250 1130 1140 1150 1160 1170 1180 1190 1200 QUERY CTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGA ::: : :: ::::: :: ::: : ::: :: : : :: :: ::: : :: :: ::::::::::: : HSCATH CTGCTTGTGGGCTATGGCACTGA---CTCAGCCTCTGGGATGGAT---TACTGGATTGTTAAAAACAGCTGGGGCACCGG 1260 1270 1280 1290 1300 1310 1320 1210 1220 1230 1240 1250 1260 1270 QUERY ATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTG---CCTCAGCA--GCCAGCTA ::::: : ::::::: : ::: :: :: : : : : :::: ::::: : :::: : :::: : HSCATH CTGGGGTGAGAATGGCTACTTCCGGATCCGCAGAG---GAACTGATGAGTGTGCAATTGAGAGCATAGCAGTGGCAGCCA 1330 1340 1350 1360 1370 1380 1390 1400 1280 1290 1300 1310 1320 1330 1340 1350 QUERY CCCCACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCA : ::: : HSCATH CACCAATTCCTAAATTGTAGGGTATGCCTTCCAGTATTTCATAATGATCTGCATCAGTTGTAAAGGGGAATTGGTATATT 1410 1420 1430 1440 1450 1460 1470 1480 --------------------------------------------------------------------------- >>RATCATC D90404 Rat mRNA for cathepsin C. 5/92 (1850 nt) initn: 114 init1: 114 opt: 204 Z-score: 164.2 expect() 0.015 61.905% identity in 168 nt overlap Entrez lookup Re-search database >RATCAT 1112-1273: -------- : 1080 1090 1100 1110 1120 1130 1140 1150 QUERY GGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCAC :::::: ::: ::: : :: ::::: ::: : : :: RATCAT ACTGGACTGAGCGACCCTTTCAACCCCTTTGAGCTGACCAATCATGCTGTTCTGCTTGTGGGCTATGGAAAAG-ATCCAG 1230 1240 1250 1260 1270 1280 1290 1300 1160 1170 1180 1190 1200 1210 1220 1230 QUERY AGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGG : : : :: : :: ::: : :: :::::::::::::: ::::::: : :::::::: : ::: RATCAT TCACTGGGTTA-----GACTACTGGATTGTCAAGAACAGCTGGGGCTCTCAATGGGGTGAGAGTGGCTACTTCCGGATCC 1310 1320 1330 1340 1350 1360 1370 1240 1250 1260 1270 1280 1290 1300 QUERY CCAAAG--ACCGGAGAA---ACCATTGTG-GAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGACGGTGA :: :: :: : ::: : :::: : : :: ::: ::::::: RATCAT GCAGAGGAACTGATGAATGTGCAATTGAGAGTATAGCCATGGCAGCCATACCGATTCCTAAATTGTAGGACCTAGCTCCC 1380 1390 1400 1410 1420 1430 1440 1450 1310 1320 1330 1340 1350 1360 1370 1380 QUERY TGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCAGTCTACCAGCCCCCGCTGTGTCGGATAC RATCAT AGTGTCCCATACAGCTTTTTATTATTCACAGGGTGATTTAGTCACAGGCTGGAGACTTTTACAAAGCAATATCAGAAGCT 1460 1470 1480 1490 1500 1510 1520 1530 --------------------------------------------------------------------------- >>HSU79415 U79415 Homo sapiens prepro dipeptidyl peptidase I (DPP-I) gene, co (4715 nt) initn: 81 init1: 81 opt: 202 Z-score: 156.4 expect() 0.015 55.634% identity in 284 nt overlap Entrez lookup Re-search database >HSU794 1015-1281: ------------ : 980 990 1000 1010 1020 1030 1040 1050 QUERY TAAGCAGGAGAAGGCCCTGATGAAGGCAGTTGCAACTGTGGGGCCCATTTCTGTTGCTATTGATGCAGGTCATGAGTCCT :::::::: : :::::: :::: : : : :::: : : HSU794 CTGCAATGAAGCCCTGATGAAGCTTGAGTTGGTCCATCATGGGCCCATGGCAGTTGCTTTTGAAGTATATGATGACTTCC 3980 3990 4000 4010 4020 4030 4040 4050 1060 1070 1080 1090 1100 1110 1120 QUERY TCCTGTTCTATAAAG---------AAGGCATTTATTT---TGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTG ::: : : : :: : : :: : : : :: :: : : ::: : :::::: ::: HSU794 TCCACTACAAAAAGGGGATCTACCACCACACTGGTCTAAGAGACCCTTTCAACCCCTTTGAGCTGACTAATCATGCTGTT 4060 4070 4080 4090 4100 4110 4120 4130 1130 1140 1150 1160 1170 1180 1190 1200 QUERY CTGGTGGTTGGCTACGGATTTGAAAGCACAGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGA ::: : :: ::::: :: ::: : ::: :: : : :: :: ::: : :: :: ::::::::::: : HSU794 CTGCTTGTGGGCTATGGCACTGA---CTCAGCCTCTGGGATGGAT---TACTGGATTGTTAAAAACAGCTGGGGCACCGG 4140 4150 4160 4170 4180 4190 4200 4210 1210 1220 1230 1240 1250 1260 1270 QUERY ATGGGGCATGGGTGGCTACGTAAAGATGGCCAAAGACCGGAGAAACCATTGTGGAATTG---CCTCAGCA--GCCAGCTA ::::: : ::::::: : ::: :: :: : : : : :::: ::::: : :::: : :::: : HSU794 CTGGGGTGAGAATGGCTACTTCCGGATCCGCAGAG---GAACTGATGAGTGTGCAATTGAGAGCATAGCAGTGGCAGCCA 4220 4230 4240 4250 4260 4270 4280 1280 1290 1300 1310 1320 1330 1340 1350 QUERY CCCCACTGTGTGAGCTGGTGGACGGTGATGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCA : :: HSU794 CACCGATTCCTAAATTGTAGGGTATCCCTTCCAGTATTTCATAATGATCTGCATCAGTTGTAAAGGGAAATTGGTATATT 4290 4300 4310 4320 4330 4340 4350 4360 --------------------------------------------------------------------------- >>HSAF001550 AF001550 Homo sapiens chromosome 16 BAC clone CIT987SK-334D11 co (78416 nt) initn: 242 init1: 81 opt: 188 Z-score: 126.4 expect() 0.044 62.651% identity in 166 nt overlap Entrez lookup Re-search database >HSAF00 1415-1573: ------: 1380 1390 1400 1410 1420 1430 1440 1450 QUERY GTGTCGGATACACACTCGAATCATTGAAGATCCGAGTGTGATTTGAATTCTGTGATATTTTCACACTGGTA-AATGTTAC ::: : : : : ::::::: : : :: ::: :: HSAF00 ATCTAATATAATTATACAATATTATAATTATGATTTTTATATTACATTACAATTATATTTTTATA----TATAATTATAT 36070 36080 36090 36100 36110 36120 36130 1460 1470 1480 1490 1500 1510 1520 QUERY CTCTATTTTAATTACTGCTATAAATAGGTTTATATTATTGATT-CACTT---ACTGACTTTGCATTTTCGTTTTTAAAAG : :::::: : :: : ::: ::: ::::: :::: ::: : :: : : ::: :::: :::::: :: HSAF00 ATATATTTTTAATA-TTATAT-TATATTTTTATTTTATATATTATAATTATAAATATTTTTATATTTATATTTTTATAAA 36140 36150 36160 36170 36180 36190 36200 36210 1530 1540 1550 1560 1570 QUERY GATGTATAAATTTTTACCT--GTTTAAATAAAATTTAATTTCAAATGT :: :: ::::::: : ::::::: :::::::::: : :: HSAF00 TATAATTATATTTTTATATAAAATTAAATATAATTTAATTTTATATAATTATAAATATTTTTATATTTTATATTTATAAT 36220 36230 36240 36250 36260 36270 36280 36290 HSAF00 TATAATTTATATTATATATTTATATTTATATATTTATATTTATTTATATTTATATATTTAAATATTTATATTTATAGTAT 36300 36310 36320 36330 36340 36350 36360 36370 --------------------------------------------------------------------------- >>AC000080 Homo sapiens Chromosome 22q11.2 Cosmid Clone 56c In DGCR Region, (44298 nt) initn: 152 init1: 101 opt: 181 Z-score: 124.2 expect() 0.1 70.000% identity in 110 nt overlap Entrez lookup Re-search database >AC0000 40- 147: ----- : 10 20 30 40 50 60 70 QUERY AGAACCGCGACCTCCGCAACCTTGAGCGGCATCCGTGGAGTGCGCCTGCAGCTACGACCGCAGCAGGAAAGCGCCGCCG ::::: :::::::: ::::: ::::::::: :: :: :: AC0000 CTCTAACTAACCTGCTCTATTGTGCCTCTAATGCCCACCCGTGCG-CTGCAGCT-CGACCCCAGCAGGAAGGCCCCTCCC 1000 1010 1020 1030 1040 1050 1060 1070 80 90 100 110 120 130 140 150 QUERY GCCAGGCCCAGCTGTGGC-CGGACAGGGACTGGAAGAGAGGACGCGGTCGAGTA-GGTGTGCACCAGCCCTGGCAACGAG :: :::::::: : : ::: :::: ::: : :::::: :: : : : : : :: :::::: AC0000 CCCGGGCCCAGCAGGCCCGCGGTCAGG--CTG-----GTGGACGCCGTAGGGGACGCTAAGCCTCAGCCCGTTGATTCCT 1080 1090 1100 1110 1120 1130 1140 160 170 180 190 200 210 220 230 QUERY AGCGTCTACCCCGAACTCTGCTGGCCTTGAGGTGGGGAAGCCGGGGAGGGCAGTTGAGGACCCCGCGGAGGCGCGTGACT AC0000 GGGTCTAGCTTGCATGCCTGGTACGTTCTCTCATCTGGTTGTTCGTCCACCTGTTCCTGCCCTCTGGGCCAGGGCTTCTT 1150 1160 1170 1180 1190 1200 1210 1220 --------------------------------------------------------------------------- >>MMU89269 U89269 Mus musculus preprodipeptidyl peptidase I mRNA, complete cd (1850 nt) initn: 105 init1: 105 opt: 177 Z-score: 141.6 expect() 0.26 60.119% identity in 168 nt overlap Entrez lookup Re-search database >MMU892 1112-1273: -------- : 1080 1090 1100 1110 1120 1130 1140 1150 QUERY GGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCAC :::::: ::: :: : :: ::::: ::: : : :: MMU892 ACTGGGCTGAGTGACCCTTTCAACCCCTTCGAGCTGACAAATCATGCTGTTTTGCTTGTGGGCTATGGAAGAG-ATCCAG 1240 1250 1260 1270 1280 1290 1300 1310 1160 1170 1180 1190 1200 1210 1220 1230 QUERY AGAATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGATGG : : :::: :::: ::: : : :::::::::::::: : ::::: : :::::::: : :: MMU892 TTACTGGGATA-----GAATACTGGATTATAAAGAACAGCTGGGGCTCTAACTGGGGGGAGAGTGGCTACTTCCGTATCC 1320 1330 1340 1350 1360 1370 1380 1240 1250 1260 1270 1280 1290 1300 QUERY CCAAAG--ACCGGAGAA---ACCATTGTG-GAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGACGGTGA :: :: :: : ::: : :::: : : :: ::: :: :::: MMU892 GCAGAGGAACTGATGAATGTGCAATTGAGAGTATAGCCGTGGCGGCCATACCGATTCCTAAATTATAGGACATAGCTCCC 1390 1400 1410 1420 1430 1440 1450 1460 1310 1320 1330 1340 1350 1360 1370 1380 QUERY TGAGGAAGGACTTGACTGGGGATGGCGCATGCATGGGAGGAATTCATCTTCAGTCTACCAGCCCCCGCTGTGTCGGATAC MMU892 AGTGTTACATACGGGTCTTTATCACTCACAGAGTGATTTAGTCACATGCTGAAGACTTTTTCAGAGCAATATCAGAAGCT 1470 1480 1490 1500 1510 1520 1530 1540 --------------------------------------------------------------------------- >>HSU51269 U51269 Human armadillo repeat protein mRNA, complete cds. 4/97 (4031 nt) initn: 101 init1: 101 opt: 174 Z-score: 134.0 expect() 0.32 62.500% identity in 144 nt overlap Entrez lookup Re-search database >HSU512 6- 147:------- : 10 20 30 40 QUERY AGAACCGCGACCTCCGCAACCTTGAGCGGCATCCGTGGAGTGCGC ::: : ::: ::: ::: ::: :: : : :: : HSU512 GATACTCCACGGTGGACCGGAGGGAGCGGAGGCCACGGGGCGCCAGCTCTGCA----GGAGAGGCCTCTGAGAAGGAACC 2970 2980 2990 3000 3010 3020 3030 3040 50 60 70 80 90 100 110 120 QUERY CTGCAGCTACGACCGCAGCAGGAAAGCGCCGCCGGCCAGGCCCAGCTGTGGC-CGGACAGGGACTGGAAGAGAGGACGCG :: : ::::: ::::::::: :: :: :: :: :::::::: : : ::: :::: ::: : :::::: HSU512 CTTGAAACTCGACCCCAGCAGGAAGGCCCCTCCCCCCGGGCCCAGCAGGCCCGCGGTCAGG--CTG-----GTGGACGCC 3050 3060 3070 3080 3090 3100 3110 130 140 150 160 170 180 190 200 QUERY GTCGAGTA-GGTGTGCACCAGCCCTGGCAACGAGAGCGTCTACCCCGAACTCTGCTGGCCTTGAGGTGGGGAAGCCGGGG :: : : : : : :: :::::: HSU512 GTAGGGGACGCTAAGCCTCAGCCCGTTGATTCCTGGGTCTAGCTTGCATGCCTGGGCCCAGGCCCAGCCTCTTGTTCTTA 3120 3130 3140 3150 3160 3170 3180 3190 --------------------------------------------------------------------------- >>MMU74683 U74683 Mus musculus dipeptidyl peptidase I precursor mRNA, complet (1767 nt) initn: 81 init1: 81 opt: 174 Z-score: 139.4 expect() 0.37 61.438% identity in 153 nt overlap Entrez lookup Re-search database >MMU746 1112-1261: ------- : 1080 1090 1100 1110 1120 1130 1140 1150 QUERY GGCATTTATTTTGAGCCAGACTGTAGCAGTGAAGACATGGATCATGGTGTGCTGGTGGTTGGCTACGGATTTGAAAGCAC :::::: ::: :: : :: ::::: ::: ::: : MMU746 ACTGGGCTGAGTGACCCTTTCAACCCCTTCGAGCTGACAAATCATGCTGTTTTGCTTGTGGGCTATGGA---AAAATTCC 1240 1250 1260 1270 1280 1290 1300 1310 1160 1170 1180 1190 1200 1210 1220 QUERY AG--AATCAGATAACAATAAATATTGGCTGGTGAAGAACAGCTGGGGTGAAGAATGGGGCATGGGTGGCTACGTAAAGAT :: : : :::: ::::: ::: : : :: ::::::::::: : ::::: :::::::: : :: MMU746 AGTTACTGGGATA-----AAATACTGGATTATAAAAAACAGCTGGGGCTCTAACTGGGGGGAAAGTGGCTACTTCCGTAT 1320 1330 1340 1350 1360 1370 1380 1230 1240 1250 1260 1270 1280 1290 1300 QUERY -GGCCAAAGACCGGAGAAACCATTGTGGAATTGCCTCAGCAGCCAGCTACCCCACTGTGTGAGCTGGTGGACGGTGATGA :: :: :: : :: :: :::: ::::: MMU746 CCGCAAAGGAACTGATGAA----TGTGCAATTGAAAGTATAGCCGTGGCGGCCATACCGATTCCTAAATTATAGGACATA 1390 1400 1410 1420 1430 1440 1450 1460 --------------------------------------------------------------------------- >>HSNFIL6 X52560 Human gene for nuclear factor NF-IL6. 4/97 (1910 nt) initn: 79 init1: 79 opt: 166 Z-score: 132.2 expect() 0.85 58.242% identity in 182 nt overlap Entrez lookup Re-search database >HSNFIL 96- 269: -------- : 60 70 80 90 100 110 120 130 QUERY GACCGCAGCAGGAAAGCGCCGCCGGCCAGGCCCAGCTGTGGCCGGACA-GGGACTGGAAGAGAGGACGCGGTCGAGTAGG :::: :: :::::::: : :: :::: : :::: HSNFIL TATAAATAACCGGGCTCAGGAGAAACTTTAGCGAGTCAGAGCCGCGCACGGGACTGGGA-AGGGGACCCACCCGAGGGTC 70 80 90 100 110 120 130 140 140 150 160 170 180 190 200 210 QUERY TGTGCACCAGCCCTGGCAACGAGAGCGTCTACCCCGAACTCTGCTGGCCTTGAGGTGGGGAAGCCGGGG----AGGGCAG ::::::::: :: : :::: : :::::: : :: : : : : :: :: : :: :: ::: HSNFIL CAGCCACCAGCCCCCTCACTAATAGCGGCCACCCCGGCAGCGGCGGCAGCAGCAGCAGCGACGCAGCGGCGACAGCTCAG 150 160 170 180 190 200 210 220 220 230 240 250 260 270 280 QUERY TTGA-GGACCCCGCGGAGGCGCGTGACTGGTTGAGCGGGCAGGCC--AGCCTCCGAGCCGGGTGGACACAGGTTTTAAAA : ::: ::::: : ::: : : : :::::::::: :: ::: :: ::::: HSNFIL AGCAGGGAGGCCGCGCACCTGCGGGCCGGCCGGAGCGGGCAGCCCCAGGCCCCCTCCCCGGGCACCCGCGTTCATGCAAC 230 240 250 260 270 280 290 300 290 300 310 320 330 340 350 360 QUERY CATGAATCCTACACTCATCCTTGCTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGG HSNFIL GCCTGGTGGCCTGGGACCCAGCATGTCTCCCCCTGCCGCCGCCGCCGCCTGCCTTTAAATCCATGGAAGTGGCCAACTTC 310 320 330 340 350 360 370 380 --------------------------------------------------------------------------- >>MUSC3A1A M18933 Mouse alpha-1 type-III collagen mRNA, 5' end. 12/88 (1485 nt) initn: 60 init1: 60 opt: 165 Z-score: 133.0 expect() 0.99 55.674% identity in 282 nt overlap Entrez lookup Re-search database >MUSC3A 548- 819: ------------ : 510 520 530 540 550 560 570 580 QUERY ACAATGGCCATGAACGCCTTTGGAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCC :: :: :: : :: :::::::: : : : : : : MUSC3A TGGCCAAAATTATTCTCCCCAATTCGACTCATATGATGTCAAGTCTGGAGTGGGAGGAATGGCTGGCTATCCGG---GAC 470 480 490 500 510 520 530 590 600 610 620 630 640 650 660 QUERY CAGGAAGGGGA--AAGTGTTCCAGGAACCTCTGTTTTATGAGGCC--CCCAGATCTGTGGATTGGAGAGAGAAAGGCTAC ::: : : : : :::::::: :: ::: :: : :: : :: ::::: : :: : :: : : : MUSC3A CAGCTGGTCCACCAGGCCTTCCAGGACCCCCTGGTTCTTCTGGACATCCTGGATCTCCTGGTTCTCCTG-GATA-CCAAG 540 550 560 570 580 590 600 610 670 680 690 700 710 720 730 740 QUERY GTGACTCCTGTGAAGAATCAGGGTCAGTGTGGTTCTTGTTGGGCTTTTAGTGCTACTGGTGCTCTTGAAGGACAGATGTT :: : : ::::: : ::::: :::: : : :: : :: :::::::::::: : ::: :: : MUSC3A GTCCCCCTGGTGAA----CCTGGTCAAGCTGGTCCGGCAGGCCCTCCAGGACCTCCTGGTGCTCTTG--GTCCAGCTGGT 620 630 640 650 660 670 680 690 750 760 770 780 790 800 810 QUERY CC----GGAAA--ACTGGGAGGCTTATCTCACTGAGTGAGCAGAATCTGGTAGACTGCTCTGGGCCTCAAGGCAATGAAG :: ::::: : : ::: : ::: :: : : : : :: :::::: :::: :::: ::: : ::: MUSC3A CCTGCTGGAAAGGATGGAGAGTCAGGAAGACCTGGACGACCTGGACCACGTGGACTGC-CTGGACCTCCAGGTATCAAAG 700 710 720 730 740 750 760 770 820 830 840 850 860 870 880 890 QUERY GCTGCAATGGTGGCCTAATGGATTATGCTTTCCAGTATGTTCAGGATAATGGAGGCCTGGACTCTGAGGAATCCTATCCA :: MUSC3A GCCCAGCTGGCATGCCTGGATTCCCTGGTATGAAAGGACACAGAGGCTTTGATGGACGCAATGGAGAAAAGGGAGAAACA 780 790 800 810 820 830 840 850 --------------------------------------------------------------------------- >>HSL145E5 Z68162 Human DNA sequence from cosmid L145E5, Huntington's Disease (25719 nt) initn: 163 init1: 97 opt: 158 Z-score: 108.5 expect() 1.3 56.604% identity in 265 nt overlap Entrez lookup Re-search database >HSL145 21- 272: ----------- : 10 20 30 40 50 60 QUERY AGAACCGCGACCTCCGCAACCTTGAGCGGCATCCGTGGAGTGCGCCTGCAGCTACGACCG :: :::: : : :: : : :: :::::: ::: : HSL145 GCTGGAGGGGGACGCCGCGCCGTCCCTAGTGGACGCGCTGCTGGAGCAGGTTGCG-CGCTTCCGGGAGCAGCTGCGAAGG 19510 19520 19530 19540 19550 19560 19570 19580 70 80 90 100 110 120 130 QUERY CAGCAGGAAAGCGCCGCCGGCCAGGCCCAGCTGTGGCCGG-AC-AGGGACTGGAAGAGAGGA----CGCGGTCGAGTAGG ::: ::: ::: ::::: : :::::::: :: : : :: :: :::: : : :::::: :: : :::: : HSL145 CAGGAGG---GCGGCGCCGCCGAGGCCCAGATGCGCCAGGTACGAGGGCGGGTACCAGAGGAGCTGCGGGAGCGAGAGTG 19590 19600 19610 19620 19630 19640 19650 140 150 160 170 180 190 200 QUERY TGTGCACCAGC--CCTGGCAACGAGAGCGTCTAC-CCCGAACTCTGCTGGCCTTGAGGTGGGGAAGCCGGGGAGGG--CA ::: : :: :: :: : : : :: :: :: : : : :: : ::::: : :: : : ::: : HSL145 CGTGTGGCGGCCGCCGGGTCCTGGGTGGGTGAACGAGCGGGCCC--CGGGTCCTGAGGGGTTGAGGGGGTACTGGGTCCT 19660 19670 19680 19690 19700 19710 19720 19730 210 220 230 240 250 260 270 280 QUERY GTTGAGGACCCCGCGGAGGCGCGTGACTGGTTGAGCGGGCAGGCCAG--CCTCCGAGCCGGGTGGACACAGGTTTTAAAA : : :: :: :: : ::: ::::: : : ::: :::: ::: ::: : : :: HSL145 GGGGTTGAGTTGGCCTCGGGTCCTGAGGGGTTGGGGGAGCA--CCAGGTCCTGGGAGTTGAGGGGGTGCCGGGTCCTGGG 19740 19750 19760 19770 19780 19790 19800 19810 290 300 310 320 330 340 350 360 QUERY CATGAATCCTACACTCATCCTTGCTGCCTTTTGCCTGGGAATTGCCTCAGCTACTCTAACATTTGATCACAGTTTAGAGG HSL145 GGTGAGGGGGCCCCGGCTCCTGAGGGGTTGGGGGAGCATCAGGTCCTGGGGGTTGAGGGGGTGCCGGGTCCTGGGGTTGA 19820 19830 19840 19850 19860 19870 19880 19890 --------------------------------------------------------------------------- >>MMCYES X67677 M.musculus c-yes mRNA. 3/93 (4550 nt) initn: 163 init1: 112 opt: 160 Z-score: 121.5 expect() 1.4 74.576% identity in 59 nt overlap Entrez lookup Re-search database >MMCYES 1510-1568: --: 1470 1480 1490 1500 1510 1520 1530 1540 QUERY GCTATAAATAGGTTTATATTATTGATTCACTTACTGACTTTGCATTTTCGTTTTTAAAAGGATGTATAAATTTTTACCTG :: ::: :::::: :::::::::: :::::::: : MMCYES TTAAATTGTTCAGCTTTGAATAATGAAGGTAACCAGAAAGTGGATTAATCTTTTTACAAGGATGTATTAATTTTTAAGGG 2910 2920 2930 2940 2950 2960 2970 2980 1550 1560 1570 QUERY TTTAAATAAAATTTAATTTCAAATGT ::: ::: :::: :: :: MMCYES GTTATATACAATTGAAATTATTCTATCCAGTCCAAGAGAAAAATCTTTTAATATTTGCATAGCATAAAAATAAAAAACAA 2990 3000 3010 3020 3030 3040 3050 3060 --------------------------------------------------------------------------- >>AC003954 Homo sapiens chromosome 5, Pac clone 162o17 (LBNL H147), complete (78416 nt) initn: 165 init1: 119 opt: 155 Z-score: 98.7 expect() 1.5 67.021% identity in 94 nt overlap Entrez lookup Re-search database >AC0039 1482-1571: ---: 1450 1460 1470 1480 1490 1500 1510 1520 QUERY GGTAAATGTTACCTCTATTTTAATTACTGCTATAAATAGGTTTATATTATTGATT-CACTTACTGACTTTGCATTTTCGT ::::::::: ::: :::::::: : : : : :: : AC0039 TTTTTGAATTGGTGATTCTTGAATAATAAGATGGGACTACTTTATATTA--AATTCCACTTACTAAGTGAACCTGTTAAT 21800 21810 21820 21830 21840 21850 21860 21870 1530 1540 1550 1560 1570 QUERY TTTTAAAAGGATGTATAAATTTTT---ACCTGTTTAAATAAAATTTAATTTCAAATGT :::::::::: : : ::::::: : : ::: : :: : :: :::: :: AC0039 TTTTAAAAGGTTTTTATAATTTTTAAAATCATTTTTATTACATTTCTATTTTAAGGGCTAAACTTTGTAGTTATATGTTA 21880 21890 21900 21910 21920 21930 21940 21950 AC0039 CTATTATATAATGTCACATCTTTTTGTGCAAGAAATAGTTGCATTGGACTGAATTTGAAATATTATCATTTCCTGTATCA 21960 21970 21980 21990 22000 22010 22020 22030 --------------------------------------------------------------------------- >>HSCATHEP3 U07371 Human cathepsin S gene, exon 3, partial cds. 8/94 (294 nt) initn: 74 init1: 74 opt: 163 Z-score: 141.9 expect() 1.6 61.719% identity in 128 nt overlap Entrez lookup Re-search database >HSCATH 414- 537: ------ : 380 390 400 410 420 430 440 450 QUERY GGACCAAGTGGAAGGCGATGCACAACAGATTATACGGCATGAATGAAGAAGGATGGAGGAGAGCAGTGTGGGAGAAGAAC ::::::::::: : : : : ::::: ::::: HSCATH CCAGGATGCAGTATGACTATGTTCTTCTTCATTATGTTTAGAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAGAAT 50 60 70 80 90 100 110 120 460 470 480 490 500 510 520 QUERY ATGAAGATGATTGAACTGCACAATCAGGA--ATACA--GGGAAGGGAAACACAGCTTCACAATGGCCATGAACGCCTTTG : ::: : : :: ::::: : ::: :: :: ::::: : : :: : :: ::: ::::::: : : : HSCATH CTAAAGTTTGTGATGCTTCACAACCTGGAGCATTCAATGGGAATGCACTCATACGATC----TGGGCATGAACCACCTGG 130 140 150 160 170 180 190 200 530 540 550 560 570 580 590 600 QUERY GAGACATGACCAGTGAAGAATTCAGGCAGGTGATGAATGGCTTTCAAAACCGTAAGCCCAGGAAGGGGAAAGTGTTCCAG :::::::: HSCATH GAGACATGGTAGGTACATTACAAGAAATCCCACTTTCACGTCTGGGTAAATATCATTTCCTTTCTGTCTCCCCAAAAGCA 210 220 230 240 250 260 270 280 --------------------------------------------------------------------------- 1575 residues in 1 query sequences 236494278 residues in 135138 library sequences Tcomplib (4 proc)[version 3.1t02 March, 1998] start: Sun Apr 26 16:31:17 1998 done: Sun Apr 26 16:38:15 1998 Scan time: 435.933 Display time: 1.133 Function used was FASTA